Article
Cardiac & Cardiovascular Systems
Andrew M. Vekstein, Julie W. Doberne, E. Hope Weissler, Charles M. Wojnarski, Chandler A. Long, Adam R. Williams, Ryan P. Plichta, Jeffrey G. Gaca, G. Chad Hughes
Summary: After limited root/ascending repair for acute type A aortic dissection, a significant proportion of patients require distal reintervention, especially for arch pathology. This study presents an institutional algorithm for the management of the arch after previous limited repair, demonstrating promising operative and long-term outcomes.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Tristan Ehrlich, Jan M. Federspiel, Rainer M. Bohle, Hans-Joachim Schaefers
Summary: A patient underwent aortic wrapping for aortic dilatation, but ten years later, further enlargement of the aortic root necessitated complete replacement. Extreme degeneration and thinning of the aorta were observed under the graft on both macroscopic and microscopic examination.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Yixiao Zhang, Yulin Wang, Jinmiao Chen, Jun Li, Yongxin Sun, Hao Lai, Chunsheng Wang, Qiang Ji
Summary: The association between sex and clinical outcomes after surgical repair of acute type A aortic dissection was studied in this research. The study found that there were no significant differences in terms of in-hospital and midterm outcomes between male and female patients who underwent extended arch repair for ATAAD. However, female patients tended to be older, have a lower body mass index, and were less likely to be current smokers compared to male patients.
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Moritz Benjamin Immohr, Arash Mehdiani, Sebastian Johannes Bauer, Hayato Ise, Yukiharu Sugimura, Artur Lichtenberg, Payam Akhyari
Summary: This study explored the application of AMDS in patients requiring additional aortic root surgery and found that although the surgery time was prolonged, the postoperative complications and mortality rate during hospitalization were comparable to conventional surgical methods.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Juntao Qiu, Xinjin Luo, Jinlin Wu, Wei Pan, Qian Chang, Xiangyang Qian, Xiaogang Sun, Bo Wei, Liang Zhang, Shen Liu, Wenxiang Jiang, Cuntao Yu
Summary: The FuWai classification is used to differentiate different types of AcDs. Different types of AcDs have varying surgical mortality rates and utilize different surgical methods, but show similar long-term outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
James A. Brown, Derek Serna-Gallegos, Arman Kilic, Sadie Longo, Danny Chu, Forozan Navid, Courtenay Dunn-Lewis, Ibrahim Sultan
Summary: The objective of this study was to determine the impact of reoperative aortic root replacement on short-term outcomes and survival. The study found that reoperative aortic root replacement provided similar outcomes and survival compared to first-time aortic root replacement.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Surgery
Eglantine Marne, Guillaume Guimbretie, Justine Mougin, Tom Le Corvec, Beatrice Guyomarch, Louis Marie De Beaufort, Antoine Buschiazzo, Jean Christian Roussel, Blandine Maurel
Summary: The study compared the impact of extensive repair using the FET technique and conventional arch repair on long-term remodelling of the descending thoracic aorta and aortic reinterventions. Results showed that the FET group had a lower rate of negative remodelling in the descending thoracic aorta at 30 days, with no significant differences in negative remodelling and reintervention rates between the two groups at 1 year.
ANNALS OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Lauren Huckaby, Ibrahim Sultan, Santi Trimarchi, Bradley Leshnower, Edward P. Chen, Derek R. Brinster, Truls Myrmel, Anthony L. Estrera, Daniel G. Montgomery, Amit Korach, Hans -Henning Eckstein, Joseph S. Coselli, Takeyoshi Ota, Clayton A. Kaiser, Kim A. Eagle, Himanshu J. Patel, Thomas G. Gleason
Summary: In-hospital mortality remains higher among women with TAAD but shows improvement in the last decade. Significant differences in presentation were noted in women, including older age and greater evidence of malperfusion. Although no distinctions in 5-year mortality or reintervention were observed, a tailored surgical approach should be considered to reduce sex disparities in early mortality rates for TAAD.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Andrzej Juraszek, Martin Czerny, Bartosz Rylski
Summary: This paper discusses new concepts and developments in the diagnosis, classification, and treatment of aortic dissection, as well as controversies surrounding the topic. It presents novel findings in the patho mechanisms of aortic dissection, including indications for preventive surgery, biomarkers, and four-dimensional (4D)-flow magnetic resonance imaging. New classifications of aortic dissections have been proposed, and recent treatment improvements such as the frozen elephant trunk approach and thoracic endovascular repair are also discussed.
TRENDS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Nerea Lopez Perez, Philippe Reymond, Mustafa Cikirikcioglu, Mathieu van Steenberghe, Tornike Sologashvili, Nicolas Murith, Thomas Perneger, Christoph Huber
Summary: This study examines the ratio between ascending and descending aorta diameters as a potential surrogate marker for decision making in cases of ascending aortic dilatation. A retrospective observational cohort study was conducted on 50 patients who underwent surgery for acute type A aorta dissection. The results suggest that the ratio between descending and ascending aorta diameters may be a useful tool for stratifying the risk of dissection.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pediatrics
Mariam Zaidi, Ganeshkumar Premkumar, Rimel Naqvi, Arwa Khashkhusha, Zahra Aslam, Adil Ali, Abdulla Tarmahomed, Amr Ashry, Amer Harky
Summary: Congenital anomalies of the aortic valve in childhood often require intervention, with treatment options including medical, percutaneous, and surgical repair or replacement. Surgical repair is typically the mainstay of treatment in paediatric cases, but limitations such as reintervention and restenosis rates exist.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Cardiac & Cardiovascular Systems
Francesco Nappi, Sandra Petiot, Antonio Salsano, Sanjeet Singh Avtaar Singh, Joelle Berger, Marisa Kostantinou, Severine Bonnet, Ivancarmine Gambardella, Fausto Biancari, Almothana Almazil, Francesco Santini, Rim Chaara, Antonio Fiore
Summary: This retrospective study analyzed data from three departments of cardiac surgery between January 2005 and December 2021 and found a higher proportion of women undergoing aortic arch repair. There were no significant differences in operative mortality and early postoperative neurological complications between men and women. Preoperative arterial lactate levels and mesenteric ischemia after surgery were significantly associated with increased operative mortality in women.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Review
Cardiac & Cardiovascular Systems
Bartosz Rylski, Oliver Schilling, Martin Czerny
Summary: Remarkable progress has been made in aortic medicine in recent decades, leading to significant changes in the understanding and treatment of thoracic aortic dissection. This state-of-the-art review article explores the mechanisms of acute aortic dissection, the impact of its entry location and dissection extension on clinical presentation and treatment decisions, and presents the latest evidence on novel treatment methods and discussions on dissection classification. Future aspects of treating acute aortic dissection are also discussed.
EUROPEAN HEART JOURNAL
(2023)
Article
Medicine, General & Internal
Feyza Memis, Carlijn G. E. Thijssen, Arjen L. Gokalp, Maximiliaan L. Notenboom, Frederike Meccanici, Mohammad Mostafa Mokhles, Roland R. J. van Kimmenade, Kevin M. Veen, Guillaume S. C. Geuzebroek, Jelena Sjatskig, Franciscus J. ter Woorst, Jos A. Bekkers, Johanna J. M. Takkenberg, Jolien W. Roos-Hesselink
Summary: This study aims to evaluate patient and procedural characteristics and compare the outcomes and mortality after surgery between elderly and non-elderly patients with ascending aortic aneurysm. The study found that elderly patients had larger aortic diameters and more cardiovascular risk factors. Short-term mortality was comparable between elderly and non-elderly patients, but the five-year survival rate was lower in elderly patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Habib Khan, Azhar Hussain, Sanjay Chaubey, Mohamed Sameh, Inga Salter, Ranjit Deshpande, Max Baghai, Olaf Wendler
Summary: In patients with AADA, surgeries performed by aortic specialists showed improved outcomes with lower 30-day mortality and better long-term survival compared to surgeries performed by non-specialist surgeons. Aortic specialists also performed more complex procedures, such as replacing more of the dissected aorta, further supporting the establishment of specialist aortic surgical services in cardiac centers.
JOURNAL OF CARDIAC SURGERY
(2021)
Letter
Cardiac & Cardiovascular Systems
Ville Kyto, Jarmo Gunn
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Markus Malmberg, Vesa Anttila, Paivi Rautava, Jarmo Gunn, Ville Kyto
Summary: This study aims to investigate the long-term outcomes of mechanical and biological valve prostheses in native mitral valve infective endocarditis patients. The results show that mechanical valve replacement is associated with lower long-term mortality compared to biological valve replacement, and a history of drug abuse does not significantly affect the results.
SCANDINAVIAN CARDIOVASCULAR JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Markus Bjurbom, Christian Olsson, Arnar Geirsson, Tomas Gudbjartsson, Jarmo Gunn, Emma C. Hansson, Vibeke Hjortdal, Anders Jeppsson, Ari Mennander, Jacob Ede, Igor Zindovic, Anders Ahlsson, Anders Wickbom, Magnus Dalen
Summary: This study aimed to evaluate the association between previous cardiac surgery and outcomes after surgery for acute type A aortic dissection. The results showed that major adverse events were more frequent in patients with previous cardiac surgery, but previous cardiac surgery itself was not an independent predictor for adverse events.
ANNALS OF THORACIC SURGERY
(2023)
Article
Surgery
Ville Rantasalo, Dan Laukka, Veikko Nikulainen, Juho Jalkanen, Jarmo Gunn, Harri Hakovirta
Summary: This study evaluates the association of aortic calcification with mortality and major adverse cardiovascular and leg events (MACEs and MALEs) in patients with peripheral artery disease (PAD). The results show that high ACI is associated with increased risk of mortality and MACEs.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Orthopedics
Anssi Arimaa, Tommi Salminen, Jani Knifsund, Ville Kyto, Petteri Lankinen, Inari Laaksonen
Summary: This study assessed the incidence of anterior cruciate ligament reconstruction (ACLR) and concomitant procedures in Finland. The overall incidence of ACLR increased from 2004 to 2014 before decreasing by 2018. Male patients had a higher incidence than females, but the incidence among females increased throughout the study period. The highest incidence of ACLR occurred in the 16-29 age group for both sexes. Concomitant procedures were performed in 32% of cases.
Article
Cardiac & Cardiovascular Systems
Carl Johan Mahn, Joakim Alfredsson, David Erlinge, Tomas Gudbjartsson, Jarmo Gunn, Stefan James, Christian H. Moller, Susanne J. Nielsen, Ulrik Sartipy, Theis Tonnessen, Anders Jeppsson
Summary: The TACSI trial aims to determine whether 1-year treatment with dual antiplatelet therapy is better than monotherapy with acetylsalicylic acid in patients with acute coronary syndrome after coronary artery bypass grafting. This pragmatic and prospective trial will enroll 2200 patients and assess outcomes such as death, myocardial infarction, stroke, and bleeding.
AMERICAN HEART JOURNAL
(2023)
Article
Clinical Neurology
Jussi P. Posti, Jori O. Ruuskanen, Ville Kyto
Summary: The study found that adults with epilepsy have a significantly increased risk of traumatic brain injury (TBI), emphasizing the importance of TBI prevention in epilepsy.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Anna Oudin, Henrik Bjursten, Daniel Oudin Astroem, Shahab Nozohoor, Khalil Ahmad, Mariann Tang, Markus Bjurbom, Emma C. Hansson, Anders Jeppsson, Christian H. Moeller, Mikko Jormalainen, Tatu Juvonen, Ari Mennander, Peter S. Olsen, Christian Olsson, Anders Ahlsson, Emily Pan, Peter Raivio, Anders Wickbom, Johan Sjogren, Arnar Geirsson, Tomas Gudbjartsson, Igor Zindovic
Summary: A study conducted in 10 Nordic cities found that national holidays and weekends have a negative impact on the incidence of surgery for acute type A aortic dissection (ATAAD), leading to a decrease in the number of surgical repairs.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Marja-Liisa Huuskonen, Tero Koistinen, Niina Sihvola, Inkeri Parkkari, Sanna Palovaara, Ville Kyto, Jussi Sipila, Sirkku Jyrkkio, Eetu Heerva
Summary: The aim of this study was to evaluate the risk of road traffic accidents (RTA) among cancer patients in Southwest Finland. The results showed that cancer diagnosis itself was not associated with increased RTA risk, but other associated symptoms, medications, comorbidities, or specific cancer subgroups may have an impact.
Article
Cardiac & Cardiovascular Systems
Ville Kyto, Paivi Rautava, Aleksi Tornio
Summary: Initiating high-dose statin therapy after myocardial infarction is associated with better long-term cardiovascular outcomes.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2023)
Article
Medicine, General & Internal
Alisa Salmivalli, Otto Ettala, Pertti Nurminen, Pekka Kinnala, Peter J. Bostrom, Ville Kyto
Summary: This study aims to compare the short- and long-term risks of PVP and TURP in the treatment of benign prostate enlargement. Retrospective study on consecutive patients in 20 hospitals in Finland showed that PVP had lower postoperative bleeding risk but higher long-term reoperation risk.
ANNALS OF MEDICINE
(2023)
Article
Clinical Neurology
Julia Aivo, Jori O. Ruuskanen, Aleksi Tornio, Paivi Rautava, Ville Kyto
Summary: This study found that not using statins after ischemic stroke is associated with adverse long-term outcomes, such as increased all-cause mortality and higher risk of cardiovascular events. Measures to improve timely statin use after stroke are needed.
Article
Cardiac & Cardiovascular Systems
Juhani S. Koskinen, Ville Kyto, Markus Juonala, Jorma S. A. Viikari, Jaakko Nevalainen, Mika Kahonen, Terho Lehtimaki, Nina Hutri-Kahonen, Tomi P. Laitinen, Paivi Tossavainen, Eero Jokinen, Costan G. Magnussen, Olli T. Raitakari
Summary: This study examines the association between childhood and adult dyslipidemia and adult carotid atherosclerotic plaques, and found that childhood dyslipidemia, even if resolved by adulthood, is still a risk factor for adult carotid plaques.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Rikhard Bjorn, Joonas Lehto, Markus Malmberg, Vesa Anttila, K. E. Juhani Airaksinen, Jarmo Gunn, Tuomas Kiviniemi
Summary: Patients with mechanical aortic valve replacement require lifelong VKA therapy for stroke prevention, although this treatment increases the risk of bleeding. The success of antithrombotic therapy and occurrence of strokes and bleeding events was assessed in 308 patients who underwent mechanical AVR. Major bleeding was 5 times more common than major stroke, indicating good efficacy but inadequate safety of stroke prevention. Gastrointestinal bleeding was the most common site of bleeding during long-term follow-up.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Urology & Nephrology
Alisa Salmivalli, Otto Ettala, Peter J. Bostrom, Ville Kyto
Summary: This study investigated postoperative mortality rates and risk factors for mortality after surgical treatment of benign prostate hyperplasia (BPH) in Finland. The study found that age, comorbidity index, and atrial fibrillation were risk factors for postoperative mortality, while laser operations may be associated with lower mortality rates compared to TURP. The study highlights the importance of carefully considering the risks and benefits of each surgical procedure for individual patients.
WORLD JOURNAL OF UROLOGY
(2022)