CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

(2014) Diana Jurk et al.   Nature Communications

Cytomegalovirus infection is associated with increased mortality in the older population

(2013) George M. Savva et al.   AGING CELL

IFN-  Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling

(2013) A. Lanna et al.   JOURNAL OF IMMUNOLOGY

Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA

(2013) S. J. Griffiths et al.   JOURNAL OF IMMUNOLOGY

The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection

(2012) David B. Bartlett et al.   AGING CELL

Aging and Atherosclerosis

(2012) Julie C. Wang et al.   CIRCULATION RESEARCH

CMV and Immunosenescence: from basics to clinics

(2012) Rafael Solana et al.   Immunity & Ageing

Cytomegalovirus-Specific T Cell Immunity Is Maintained in Immunosenescent Rhesus Macaques

(2011) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

Hallmark Features of Immunosenescence Are Absent in Familial Longevity

(2010) E. Derhovanessian et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

(2010) P. J. E. J. van de Berg et al.   JOURNAL OF IMMUNOLOGY

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

KLRG1—more than a marker for T cell senescence

(2009) Sian M. Henson et al.   AGE

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

(2009) S. M. Henson et al.   BLOOD

Accelerated Telomere Shortening in Leukocyte Subpopulations of Patients With Coronary Heart Disease

(2009) Ioakim Spyridopoulos et al.   CIRCULATION

Immunobiology of Human Cytomegalovirus: from Bench to Bedside

(2009) T. Crough et al.   CLINICAL MICROBIOLOGY REVIEWS

Persistent pathogens linking socioeconomic position and cardiovascular disease in the US

(2008) A. M Simanek et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cytomegalovirus and human immunosenescence

(2008) Graham Pawelec et al.   REVIEWS IN MEDICAL VIROLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY

Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

(2008) Sven Koch et al.   Immunity & Ageing