Article
Nutrition & Dietetics
Nahla Al-Bayyari, Hayder Al-Domi, Faheem Zayed, Ra'ed Hailat, Arieanna Eaton
Summary: The study demonstrated that weekly treatment with 50,000 IU of vitamin D-3 can improve 25(OH)D levels and decrease hirsutism scores and androgen levels in overweight women with PCOS. These results may lead to increased fertility and better reproductive health for these patients.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Yuqin Zhang, Zhihua Qu, Ting Lu, Xiaowen Shao, Meili Cai, Diliqingna Dilimulati, Xinxin Gao, Weiqing Mao, Fan Hu, Lili Su, Qiong Liao, Ting Han, Manna Zhang, Shen Qu
Summary: This study aimed to investigate the effects of dulaglutide and a calorie-restricted diet on visceral adipose tissue and metabolic profiles in polycystic ovary syndrome patients. The results showed that dulaglutide combined with a calorie-restricted diet was more effective in reducing visceral adipose tissue and improving clinical outcomes compared to a calorie-restricted diet alone.
Article
Plant Sciences
Javad Heshmati, Ashraf Moini, Mahdi Sepidarkish, Mojgan Morvaridzadeh, Masoud Salehi, Andriko Palmowski, Maryam Farid Mojtahedi, Farzad Shidfar
Summary: The study found that using curcumin in PCOS patients can effectively improve blood sugar and androgen levels, and is safe and reliable. Longer trials with different dosages are needed to confirm these findings.
Article
Endocrinology & Metabolism
Meili Cai, Xiaowen Shao, Feng Xing, Yuqin Zhang, Xinyu Gao, Qiongjing Zeng, Diliqingna Dilimulati, Shen Qu, Manna Zhang
Summary: The study demonstrates that canagliflozin is not inferior to metformin in improving insulin resistance in PCOS patients, with significant benefits in improving menstrual pattern, reducing body weight and total fat mass, and decreasing triglyceride levels.
DIABETES OBESITY & METABOLISM
(2022)
Article
Multidisciplinary Sciences
Biyun Zhang, Xiuhua Yao, Xingming Zhong, Yang Hu, Jianying Xu
Summary: This study systematically evaluated the effects of vitamin D supplementation on patients with PCOS. The results showed that vitamin D supplementation increases serum vitamin D level and endometrial thickness, reduces serum hs-CRP, parathyroid hormone, total cholesterol, and total testosterone level. However, there were no significant differences in levels of SHBG and mF-G score between the vitamin D and control groups.
Article
Chemistry, Medicinal
Masoome Jabarpour, Ashraf Aleyasin, Maryam Shabani Nashtaei, Fardin Amidi
Summary: This study investigated the effect of astaxanthin on infertile polycystic ovarian syndrome (PCOS) patients. The results showed that astaxanthin improved insulin metabolism, lipid profile parameters, and oxidative stress levels in these patients. The study suggests that astaxanthin may be an effective and safe supplement.
PHYTOTHERAPY RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Firoozeh Tarkesh, Bahia Namavar Jahromi, Najmeh Hejazi, Golazin Hoseini
Summary: This study aimed to assess the effect of vitamin K2 on depression status in patients with PCOS. The results indicated that the administration of Menaquinone-7 significantly improved depression status.
Review
Biochemistry & Molecular Biology
Flavia Di Bari, Antonino Catalano, Federica Bellone, Gabriella Martino, Salvatore Benvenga
Summary: PCOS is the most common endocrine disorder among premenopausal women, with implications for reproduction, metabolism, cardiovascular health, and psychological well-being. Vitamin D deficiency is often seen in women with PCOS and plays a significant role in bone health and the pathophysiological link between PCOS and bone metabolism.
Article
Food Science & Technology
Seiichiro Aoe, Takanori Kawano, Junko Naito, Norihisa Nishida, Madoka Takahashi
Summary: This study aimed to investigate the effect of supplementation with paramylon-rich Euglena gracilis EOD-1 powder on reducing visceral fat obesity in moderately obese Japanese individuals. The results showed that EOD-1 intake led to a significant reduction in VFA in male subjects and increased serum adiponectin levels. Additionally, it also resulted in a significant decrease in serum HbA1c levels, indicating potential benefits in preventing visceral fat obesity and improving glucose homeostasis.
FOOD SCIENCE & NUTRITION
(2023)
Article
Nutrition & Dietetics
Man Abdullah Bindayel
Summary: The study showed that women with PCOS have lower vitamin D levels and a higher obesity rate compared to controls. Fewer patients with PCOS consumed milk and dairy products, and were exposed to sunlight, than controls.
FRONTIERS IN NUTRITION
(2021)
Article
Obstetrics & Gynecology
Qidan Wen, Min Hu, Maohua Lai, Juan Li, Zhenxing Hu, Kewei Quan, Jia Liu, Hua Liu, Yanbing Meng, Suling Wang, Xiaohui Wen, Chuyi Yu, Shuna Li, Shiya Huang, Yanhua Zheng, Han Lin, Xingyan Liang, Lingjing Lu, Zhefen Mai, Chunren Zhang, Taixiang Wu, Ernest H. Y. Ng, Elisabet Stener-Victorin, Hongxia Ma
Summary: In women with PCOS and IR, acupuncture was not more effective than metformin or sham acupuncture in improving insulin sensitivity. However, acupuncture showed fewer gastrointestinal side effects compared to metformin, suggesting it may be a non-pharmacological treatment option with lower risk. Further research is needed to evaluate the combined effects of acupuncture and metformin on insulin sensitivity in these women.
HUMAN REPRODUCTION
(2022)
Article
Pharmacology & Pharmacy
Xin Yuan, Jianshu Yang, Danlin Sun, Kaiming Luo, Xiaohong Jiang, Long Wang, Shoukui Xiang, Yijie Jiang, Kele Ge, Zhiyang Zhou, Bowen Li, Fei Hua
Summary: This study aimed to evaluate the influence of 1,25-dihydroxyvitamin D (1,25(OH)(2)D) on metabolic dysfunction in a rat model of polycystic ovary syndrome (PCOS) and elucidate its underlying mechanism. The results showed that 1,25(OH)(2)D inhibited hepatic diacylglycerol (DG) accumulation in PCOS rats, thereby ameliorating their metabolic dysfunction.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Cell Biology
Karolina Pich, Jesika Rajewska, Kinga Kaminska, Marcelina Tchurzyk, Agata Szlaga, Patryk Sambak, Anna Blasiak, Malgorzata Grzesiak, Agnieszka Rak
Summary: This study aimed to investigate the impact of VD3 supplementation on RARRES2 and ADIPOQ levels in the uterus of PCOS rats. The findings showed that VD3 supplementation restored the levels of these adipokines and increased the expression of their receptors in the uterus of PCOS rats, indicating a new mechanism of VD3 action in uterine physiology.
Article
Biochemistry & Molecular Biology
Shabnam Shahmoradi, Hossein Chiti, Mahdi Tavakolizadeh, Robabeh Hatami, Nima Motamed, Marjan Ghaemi
Summary: This study aimed to evaluate the effects of magnesium supplements on anthropometric, clinical, and metabolic parameters in women with polycystic ovary syndrome (PCOS). The results showed a significant reduction in serum insulin levels and insulin resistance in the group receiving magnesium supplements. Furthermore, magnesium supplements led to a decrease in total cholesterol, low-density lipoprotein, and fasting blood sugar, as well as an increase in high-density lipoprotein levels. However, there were no significant differences in anthropometric parameters or blood pressure between the two groups before and after intervention. Overall, the use of magnesium supplements can improve the metabolic status of PCOS patients by improving insulin resistance and modulating lipid profiles.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Agriculture, Multidisciplinary
Dongdong Zhang, Xiaoqin Zhong, Cheng Cheng, Zhiwei Su, Yuan Xue, Yaping Liu, Yujing Zhang, Mingming Feng, Ze Xu, Tong Zhao, Luoya Zhang, Haoyue Huang, Wenjie Li, Xing Li
Summary: The potential role of vitamin D in beta-cell function is still debated. A randomized, placebo-controlled trial was conducted to investigate the effect of vitamin D and calcium supplementation on beta-cell function in a Chinese population with prediabetes. The results showed that oral administration of vitamin D and calcium increased insulin secretion. Vitamin D-insufficient individuals had improved glucose tolerance after treatment with vitamin D + calcium. Further research is needed to confirm these findings. Given the low vitamin D content in natural foods, fortification of processed foods with vitamin D is necessary.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Medicine, General & Internal
Rasoul Zarrin, Parvin Ayremlou, Farzaneh Ghassemi
IRANIAN RED CRESCENT MEDICAL JOURNAL
(2017)
Article
Public, Environmental & Occupational Health
Sakineh Nouri Saeidlou, Fariba Babaei, Parvin Ayremlou, Rasoul Entezarmahdi
PUBLIC HEALTH NUTRITION
(2018)
Article
Nutrition & Dietetics
Hojjat Naseri, Rasoul Zarrin, Parvin Ayremlou, Mir Amir Aghdashi, Seyedmostafa Seyedmardani
CLINICAL NUTRITION ESPEN
(2020)
Article
Cardiac & Cardiovascular Systems
Esmaeel Gholizadeh, Parvin Ayremlou, Sakineh Nouri Saeidlou
JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH
(2020)
Article
Endocrinology & Metabolism
Mona Golmohammadi, Rasoul Zarrin, Parvin Ayremlou
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2020)
Article
Medicine, General & Internal
Fatemeh Shojasaadat, Parvin Ayremlou, Asad Hashemi, Alireza Mehdizadeh, Rasoul Zarrin
JOURNAL OF RESEARCH IN MEDICAL SCIENCES
(2019)
Article
Medicine, General & Internal
Sakineh Nouri Saeidlou, Fatemeh Rezaiegoyjeloo, Parvin Ayremlou, Fariba Babaie
INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE
(2016)
Article
Oncology
Parvin Ayremlou, Seyed Mohsen Razavi, Masoud Solaymani-Dodaran, Masoud Vakili, Mohsen Asadi-Lari
IRANIAN JOURNAL OF CANCER PREVENTION
(2012)
Article
Endocrinology & Metabolism
Sakineh Nouri Saeidlou, Fariba Babaei, Parvin Ayremlou
JOURNAL OF OBESITY
(2014)