Article
Materials Science, Multidisciplinary
Javier Faes, Ruben Gonzalez, Antolin Hernandez Battez, David Blanco, Alfonso Fernandez-Gonzalez, Jose Luis Viesca
Summary: In this study, three novel fatty acid anion-based ionic liquids showed similar tribological behavior as lubricants for various material pairs, including steel, aluminum alloy, bronze, cast iron, and tungsten carbide. The corrosion behavior of the ionic liquids was mainly observed on the bronze surface, while XPS analysis indicated low chemical interaction with the surfaces of the tested materials.
Article
Engineering, Mechanical
Shuang Yue, Xing Gao, Guowang Lu, Shuliang Zang, Guichun Deng, Feiming Wang
Summary: Two novel halogen-free liquid additives, [DHB][BScB] and [MA-BIm][BScB], were synthesized and evaluated for the first time in 500 N base oil using a 4-ball machine, showing a significant decrease in friction coefficient and excellent corrosion resistance. XPS and SEM analysis revealed the formation of chemical films on the worn steel surface, indicating a possible competitive adsorption mechanism between cations and anions.
TRIBOLOGY INTERNATIONAL
(2021)
Review
Environmental Sciences
Gaurav Choudhary, Jyoti Dhariwal, Moumita Saha, Shruti Trivedi, Manoj K. Banjare, Rahul Kanaoujiya, Kamalakanta Behera
Summary: Ionic liquids (ILs) are green designer solvents with high boiling point and low volatility that have vast application potential in various scientific and technological domains. They can be effectively modified for desired applications by adjusting the structure of the cationic and/or anionic part. ILs are extensively used in energy applications, such as fuel cells, lithium-ion batteries, supercapacitors (SCs), and solar cells, due to their distinctive properties like low volatility, high thermal and electrochemical stability, and better ionic conductivity. This review highlights the use of ILs as unique green designer materials in energy storage and conversion devices, demonstrating their promising prospects for next-generation green energy technologies.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Shinichi Koguchi, Haruto Fujita, Yuga Shibuya
Summary: Ionic liquids have unique physical properties, making them widely used in various fields, especially in synthetic organic chemistry as reaction solvents. In this paper, we propose a new organic synthetic method using an ionic liquid-supported anthraquinone photocatalyst for the synthesis of benzoic acid derivatives. This environmentally friendly process allows the reuse of both the reaction solvent and catalyst, and it has a simple post-reaction treatment. This is the first report on the synthesis of benzoic acid derivatives via the cleavage of vicinal diols using light and an ionic-liquid-supported catalyst.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Engineering, Environmental
Jiajia Liu, Yingjie Xu
Summary: This paper presents the capacity and absorption mechanism of NOx absorption by ionic liquids (ILs), as well as strategies for enhancing NOx capacity through functionalized ILs. The active N or O sites in functionalized ILs react with the dimer of NO (N2O2), resulting in high absorption capacity. In addition, ILs with [NO3](-) show better performance in catalyzing NO conversion into HNO3 due to their strong oxidization capability.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Polymer Science
Nahir Dib, Cristian M. O. Lepori, N. Mariano Correa, Juana J. Silber, R. Dario Falcone, Luis Garcia-Rio
Summary: This review discusses the formation and application of biocompatible water-in-oil microemulsions known as reverse micelles (RMs), emphasizing the use of biocompatible non-polar solvents and ionic liquids to create organized systems aligned with Green Chemistry principles. The versatility and importance of RMs in drug delivery and food science are highlighted, with a focus on the modification of properties through changes in surfactant and external solvents. The study emphasizes the need for deep analysis to understand the diverse properties of these novel systems.
Article
Energy & Fuels
Yue Zhao, Jing Tong
Summary: The large number of phenolic compounds in coal tar and coal-converted oil increases the cost and difficulty of processing and transportation. Efficient separation methods for phenolic compounds are of great industrial significance. By introducing hydroxyl functional groups into the cations of ionic liquids, eight ionic liquids were synthesized and their separation properties for phenol in model oil were studied. The hydroxyl modified ionic liquids showed good extraction performance for phenol, with choline propionate ionic liquids exhibiting the best separating capacity.
Article
Chemistry, Physical
Madhur Babu Singh, Pallavi Jain, Preeti Chaudhary, Indra Bahadur, Kashmiri Lal, Vinod Kumar, Prashant Singh, Himani, Anirudh Pratap Singh Raman
Summary: Ionic liquids (ILs) have a wide range of features, uses, and environmentally friendly nature, making them potential substitutes for organic solvents in addressing pollution. ILs possess unique thermal, physical, chemical, and biological properties, which can be modified by altering their cationic and anionic parts. Their applications in protein stabilization, organic transformation, nanomaterials, etc., indicate their significant impact on research and development.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Applied
Qiang Li, Yulan Hu, Bingjian Zhang
Summary: This study successfully synthesized two tetraalkylphosphonium polyoxometalate ionic liquids with excellent antibacterial activity and prepared hydrogels containing these ILs, showing that hydrogels with higher chitosan content exhibit better antibacterial efficacy. This may provide a new strategy for combating bacterial communities colonizing ancient artworks.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Claudio Ferdeghini, Andrea Mezzetta, Felicia D'Andrea, Christian Silvio Pomelli, Lorenzo Guazzelli, Luca Guglielmero
Summary: This study provides a preliminary comparative evaluation of the effect of linker chain length and the size of aliphatic ammonium rings on the thermal and solubility properties of bromide dicationic ionic liquids.
Article
Chemistry, Multidisciplinary
Marika Turek, Robert Biczak, Barbara Pawlowska, Ewa Rozycka-Sokolowska, Krzysztof Owsianik, Bernard Marciniak, Piotr Balczewski
Summary: The use of optically active forms of commercial chiral herbicides may be more effective and environmentally safer. This study synthesized a series of chiral quaternary ammonium salts and investigated their selective toxicity towards aquatic bacteria and terrestrial plants. The results showed that these salts exhibited enantioselective toxicity towards all tested organisms.
Article
Chemistry, Multidisciplinary
Yuval Simha, Gil Daniels, Amalya Goldman, Elihay Kuniavsky, Dmitry Tsvelikhovsky
Summary: A new strategy for direct access to fully substituted polycyclic imidazolium salts using alpha-enaminones and proline as the reagents is reported. This open-flask operation is a catalyst-, metal-, and Lewis acid-free green process, which does not require an ion-exchange step. It can produce good yields with minimal formation of side products, and is not limited to aryl substituents.
Review
Energy & Fuels
Abdolreza Farhadian, Azam Shadloo, Xin Zhao, Roman S. Pavelyev, Kiana Peyvandi, Zhengsong Qiu, Mikhail A. Varfolomeev
Summary: Gas hydrate formation is a serious challenge for the oil and gas industry, causing safety, environmental, and economic problems. Current kinetic hydrate inhibitors (KHIs) are not biodegradable, cheap, and eco-friendly. This report reviews efforts to develop KHIs with higher biodegradability and emphasizes the need for cheaper and greener options.
Article
Chemistry, Analytical
Rima D. Alharthy, C. E. El Shafiee, M. I. Nessim, R. I. Abdallah, Y. M. Moustafa, M. Wafeek, D. A. Ismail, M. M. H. Khalil, R. A. El-Nagar
Summary: The study aims to develop new amphiphilic dicationic ionic liquids (Ia, Ib, and Ic) as potential oil spill dispersants. These ILs demonstrated good dispersion effects at different temperatures and showed slight toxicity in acute toxicity tests against fish. The synthesized ILs can be considered as sustainable materials for dispersing oil spills.
Article
Biotechnology & Applied Microbiology
Ziyuan Liu, Jue Kou, Yi Xing, Chunbao Sun, Yuxin Zhang
Summary: This study utilizes a novel leaching system based on dicyandiamide ionic liquids to evaluate the effectiveness of iodination for leaching gold from typical e-waste. The results show promising gold leaching efficiency and a significant reduction in iodine consumption when using the leaching system.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
Matilde Vieira Sanches, Rosa Freitas, Matteo Oliva, Angelica Mero, Lucia De Marchi, Alessia Cuccaro, Giorgia Fumagalli, Andrea Mezzetta, Greta Colombo Dugoni, Monica Ferro, Andrea Mele, Lorenzo Guazzelli, Carlo Pretti
Summary: The traditional use of organic solvents is being rethought due to their high volatility, toxicity, and interaction with biological membranes. Green Chemistry focuses on developing sustainable and cost-effective solvent alternatives such as Ionic Liquids (ILs), bio-based solvents, and natural deep eutectic solvents (NADESs). This study screened 15 NADESs for ecotoxicity using marine and freshwater bioassays, finding no toxicity to invertebrates but potential biostimulation effects on algae. However, the intentional or accidental release of NADESs into aquatic systems may pose risks to ecosystem functioning.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
J. Afonso, A. Mezzetta, I. M. Marrucho, L. Guazzelli
Summary: The establishment of Deep Eutectic Solvents (DESs) as a new class of green solvents was initially based on naive comparisons with Ionic Liquids (ILs), but further research has emphasized the need for a thermodynamic definition and differentiation from other solvents. This perspective review presents experimental and computational data to dispel myths about DESs and make fair comparisons with other solvents, such as ILs, eutectic solvents (ESs), and volatile organic compounds (VOCs). The unique potential of DESs in biopolymer dissolution and treatment is highlighted, along with considerations for recycling and techno-economic aspects.
Article
Biochemistry & Molecular Biology
Brunella Grassiri, Andrea Mezzetta, Giuseppantionio Maisetta, Chiara Migone, Angela Fabiano, Semih Esin, Lorenzo Guazzelli, Ylenia Zambito, Giovanna Batoni, Anna Maria Piras
Summary: The study evaluated the use of ionic liquids (ILs) as functional excipients for solubilizing and stabilizing diacerein (DIA) in eye drop formulations and prolonging its ocular residence time. Two ILs based on natural zwitterionic compounds were investigated: L-carnitine C6 alkyl ester bromide (Carn6) and betaine C6 alkyl ester bromide (Bet6). The ILs demonstrated solubilizing, stabilizing, mucoadhesive, and antimicrobial properties, with potential for future use in ophthalmic applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Physics, Applied
Nicola Melchioni, Giacomo Trupiano, Giorgio Tofani, Riccardo Bertini, Andrea Mezzetta, Federica Bianco, Lorenzo Guazzelli, Fabio Beltram, Christian Silvio Pomelli, Stefano Roddaro, Alessandro Tredicucci, Federico Paolucci
Summary: Controlling charge density in low-dimensional materials using an electrostatic potential is a powerful tool to explore and manipulate their electronic and optical properties. Ionic liquid (IL) gating, which only requires a metallic electrode in contact with IL, provides an alternative method with excellent gating properties. However, many ILs are not suitable for optical experiments in the mid-IR region due to low optical transparency and degradation. In this study, we present two electrolytes based on bromide ILs dissolved in PMMA, which can achieve high charge densities and exhibit optical transparency, making them promising candidates for electronic and mid-IR optoelectronic devices.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Physical
Angelica Mero, Spyridon Koutsoumpos, Panagiotis Giannios, Ilias Stavrakas, Konstantinos Moutzouris, Andrea Mezzetta, Lorenzo Guazzelli
Summary: Within the field of green chemistry, deep eutectic solvents (DESs) are becoming increasingly important due to their unique physicochemical properties. In this study, a comparative analysis was conducted on six different DESs to investigate the effects of various parameters such as the nature of the hydrogen bond acceptor (HBA) and donor (HBD) and their molar ratio on properties including density, viscosity, refractive index, thermal stability, and thermal behavior. The results showed that DESs based on ethylene glycol (EG) exhibited the lowest density and viscosity, while those based on glycerol (Gly) had the highest values. Switching from choline chloride (ChCl) to betaine (Bet) as the HBA resulted in higher viscosity and density. Increasing the amount of HBD in the DESs led to lower viscosity, increased density for Gly-based DESs, and decreased density for EG and levulinic acid (LevA)-based DESs. The refractive index decreased with increasing HBD portion, but using ChCl instead of Bet as the HBA resulted in a higher refractive index. The thermal stability of the DESs was strongly influenced by the HBD used, with EG-based DESs being less stable than LevA-based ones and Gly-based DESs exhibiting the highest stability. Additionally, three characteristic mass loss events were observed in all DESs, attributed to the evaporation/degradation of the HBD, HBD-HBA interaction, and the HBA. Finally, differential scanning calorimetry (DSC) analyses showed that all DESs can be used as solvents due to their liquid state at room temperature and their ability to maintain liquid state over a wide temperature range.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Elvira Spatolisano, Giorgia De Guido, Vito Andrea Sangiorgio, Laura A. Pellegrini, Andrea Mezzetta, Lorenzo Guazzelli, Alberto Renato de Angelise, Lucia Bonoldi
Summary: Hydrogen sulfide (H2S) is a critical issue due to increased sulfur content and stricter environmental regulations. The HydroClaus process by Eni S.p.A. can convert H2S into a hydrophilic mixture of sulfur and sulfur-rich compounds for use as fertilizer. This study proposes an improved configuration for efficient water management and successfully demonstrated the process operability at the bench scale.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Pharmacology & Pharmacy
Aida Cavallo, Tamer Al Kayal, Angelica Mero, Andrea Mezzetta, Anissa Pisani, Ilenia Foffa, Cecilia Vecoli, Marianna Buscemi, Lorenzo Guazzelli, Giorgio Soldani, Paola Losi
Summary: Marine collagen, derived from marine organisms, is an abundant and eco-friendly source of collagen that possesses several advantages over mammalian collagen such as easy extraction, water solubility, avoidance of transmissible diseases, and antibacterial activity. This study investigated the use of collagen extracted from basa fish skin for the development of a bioink for 3D bioprinting of a bilayered skin model. The bioink was successfully formulated and showed good printability, supporting cell viability and proliferation of fibroblasts and keratinocytes.
Article
Biochemistry & Molecular Biology
Sharon Monaci, Daniela Minudri, Lorenzo Guazzelli, Andrea Mezzetta, David Mecerreyes, Maria Forsyth, Anthony Somers
Summary: Corrosion is a major problem that affects structures and buildings, leading to premature failure and economic loss. Biobased lignin and ionic liquids have shown potential as corrosion inhibitors. This study investigated the inhibitory properties of new biobased lignin ionic liquids and found that one of them exhibited promising performance.
Article
Engineering, Biomedical
Aida Cavallo, Tamer Al Kayal, Angelica Mero, Andrea Mezzetta, Lorenzo Guazzelli, Giorgio Soldani, Paola Losi
Summary: Three-dimensional bioprinting with a blend of fibrinogen and alginate-based bioink has been successfully used to print skin equivalents with a tissue-like structure resembling native skin. This study demonstrates the potential of bioprinting technology as a promising approach for wound healing applications.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xuemei Liu, Chaonan Cui, Shuoshuo Wei, Jinyu Han, Xinli Zhu, Qingfeng Ge, Hua Wang
Summary: This study presents a new strategy for designing efficient photocatalysts that can convert CO2 into hydrocarbons by utilizing synergistic catalytic sites. The findings provide a solution for the selective photocatalytic reduction of CO2 to CH4.
Article
Chemistry, Multidisciplinary
Chengxian Hu, Dan Wang, Lu Wang, Ying Fu, Zhengyin Du
Summary: A novel one-pot, three-component reaction conducted under electrochemical conditions was studied. The reaction involved 2-aminothiophenols, aldehydes, and malononitrile, using TBABF4 as an electrolyte and CuI as a catalyst. The proposed reaction mechanism suggested that CuI served as an electron relay. This method offers simplified operation, high atom economy, and mild reaction conditions.
Article
Chemistry, Multidisciplinary
Zhi Yang, Yu Chen, Linxi Wan, Yuxiao Li, Dan Chen, Jianlin Tao, Pei Tang, Fen-Er Chen
Summary: A highly enantioselective method for the complete hydrogenation of pyrimidinium salts using Ir/(S,S)-f-Binaphane complex as the catalyst was developed. This method provides easy access to fully saturated chiral hexahydropyrimidines, which are prevalent in many bioactive molecules. The reactions exhibit high yields and enantioselectivities under mild reaction conditions without additives. Successful application of this methodology in a continuous flow fashion further extends its practical utility.
Article
Chemistry, Multidisciplinary
Tina Jeoh, Jennifer Danger Nill, Wujun Zhao, Sankar Raju Narayanasamy, Liang Chen, Hoi-Ying N. Holman
Summary: In this study, the enzymatic hydrolysis of cellulose was investigated using real-time infrared spectromicroscopy. The spatial heterogeneity of cellulose was found to impact the hydrolysis kinetics. Hydration affected cellulose ordering, and Cel7A preferentially removed less extensively hydrogen bonded cellulose.
Article
Chemistry, Multidisciplinary
Tiphaine Richard, Walid Abdallah, Xavier Trivelli, Mathieu Sauthier, Clement Dumont
Summary: An effective method of grafting functionalities onto lignin based on glycerol carbonate has been developed using an efficient nickel-catalysed telomerisation reaction. This method allows lignin to have new reactive functions and reduces the glass transition temperatures of modified lignins, thereby expanding the application range of lignin-based resins.
Article
Chemistry, Multidisciplinary
Jing Qi, Xiyan Wang, Gan Wang, Srinivas Reddy Dubbaka, Patrick ONeill, Hwee Ting Ang, Jie Wu
Summary: This study presents a green and environmentally friendly approach for the synthesis of imides using electrocatalytic oxidation with H2O as the oxygen source. The method eliminates the need for toxic or expensive oxidants and achieves high yields under mild reaction conditions. It shows broad substrate compatibility and potential for industrial applications.
Article
Chemistry, Multidisciplinary
Babasaheb Sopan Gore, Lin-Wei Pan, Jun-Hao Lin, Yi-Chi Luo, Jeh-Jeng Wang
Summary: Here, we report a visible light-promoted intramolecular radical cascade reaction for the construction of fluorenol and naphthalene-fused cyclopropyl carbaldehyde derivatives. This method offers mild reaction conditions, a broad substrate scope, excellent step efficiency, and scalability, without the need for external chemical oxidants. The novelty of this protocol was demonstrated by synthesizing chrysene analogs and performing late-stage functionalizations.
Article
Chemistry, Multidisciplinary
Juho Antti Sirvio, Idamaria Romakkaniemi, Juha Ahola, Svitlana Filonenko, Juha P. Heiskanen, Ari Ammala
Summary: This article discusses the method of using supramolecular interaction between an aromatic hydrogen bond donor and lignin to achieve rapid delignification of softwood at low temperatures.
Article
Chemistry, Multidisciplinary
Yunyan Meng, Chunxiang Pan, Na Liu, Hongjiang Li, Zixiu Liu, Yao Deng, Zixiang Wei, Jianbin Xu, Baomin Fan
Summary: A novel visible light-driven synthesis method for 2,3-diamines has been developed, which has mild conditions, avoids the use of metal reagents, and can synthesize diamines and diols in one pot.
Article
Chemistry, Multidisciplinary
Mingqing Huang, Haiyang Huang, Mengyao You, Xinxin Zhang, Longgen Sun, Chao Chen, Zhichao Mei, Ruchun Yang, Qiang Xiao
Summary: A direct air-oxidized strategy for the synthesis of benzo[b]phosphole oxides was developed in this study. Arylphosphine oxides were transformed into phosphinoyl radicals, which were further combined with various alkynes to achieve the desired products. DFT calculations revealed the mechanism of phosphinoyl radical formation.
Article
Chemistry, Multidisciplinary
Anwei Wang, Jiayin Huang, Chunsheng Zhao, Yu Fan, Junfeng Qian, Qun Chen, Mingyang He, Weiyou Zhou
Summary: This study demonstrates an innovative strategy for the aerobic oxidation of C(sp(3))-H bonds using gamma-valerolactone. By optimizing the reaction conditions and utilizing specific catalysts, efficient oxidation of C(sp(3))-H bonds is achieved with good chemoselectivity in certain cases.
Article
Chemistry, Multidisciplinary
Shun Li, Likai Tong, Zhijian Peng, Bo Zhang, Xiuli Fu
Summary: Sulfide compounds show promise as electrocatalysts for water splitting, but their performance is limited by factors such as limited active sites and hindered substance transport. This study successfully prepared a high-entropy sulfide (ZnCoMnFeAlMg)(9)S-8, which reduced grain size and increased specific surface area, enabling the realization of a dual-functional catalyst with multiple catalytic sites. High entropy also modulated the electronic properties of sulfides, reducing the potential energy barrier for hydrolysis. This research introduces a new approach for functionalizing high entropy nanomaterials and improves the performance of water splitting catalysts.
