Insect models of central nervous system energy metabolism and its links to behavior

Live imaging using a FRET glucose sensor reveals glucose delivery to all cell types in the Drosophila brain

(2018) Anne Volkenhoff et al.   JOURNAL OF INSECT PHYSIOLOGY

The glia of the adult Drosophila nervous system

(2017) Malte C. Kremer et al.   GLIA

Profiling the proteomics in honeybee worker brains submitted to the proboscis extension reflex

(2017) Anally Ribeiro da Silva Menegasso et al.   Journal of Proteomics

Metabolite transport across the mammalian and insect brain diffusion barriers

(2017) Astrid Weiler et al.   NEUROBIOLOGY OF DISEASE

Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory

(2017) Pierre-Yves Plaçais et al.   Nature Communications

Mitochondrial specific therapeutic targets following brain injury

(2016) H.M. Yonutas et al.   BRAIN RESEARCH

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Neuronal energy consumption: biophysics, efficiency and evolution

(2016) Jeremy E Niven   CURRENT OPINION IN NEUROBIOLOGY

Astrocytic glutamate transport regulates a Drosophila CNS synapse that lacks astrocyte ensheathment

(2016) Sarah E. MacNamee et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Accumulation of Laminin Monomers in Drosophila Glia Leads to Glial Endoplasmic Reticulum Stress and Disrupted Larval Locomotion

(2016) L. M. Petley-Ragan et al.   JOURNAL OF NEUROSCIENCE

Age- and brain region-specific differences in mitochondrial bioenergetics in Brown Norway rats

(2016) Jignesh D. Pandya et al.   NEUROBIOLOGY OF AGING

Editorial: Glial Cell Biology and Neurological Disease

(2016) James Donald Lechleiter   NEUROBIOLOGY OF DISEASE

A genetically encoded biosensor for visualising hypoxia responsesin vivo

(2016) Tvisha Misra et al.   Biology Open

Molecular characterization of Tps1 and Treh genes in Drosophila and their role in body water homeostasis

(2016) Miki Yoshida et al.   Scientific Reports

Glial Glycolysis Is Essential for Neuronal Survival in Drosophila

(2015) Anne Volkenhoff et al.   Cell Metabolism

Molecular Signatures of Major Depression

(2015) Na Cai et al.   CURRENT BIOLOGY

Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris)

(2015) Christopher Moffat et al.   FASEB JOURNAL

Aggression is associated with aerobic glycolysis in the honey bee brain1

(2015) S. Chandrasekaran et al.   GENES BRAIN AND BEHAVIOR

Decreased mitochondrial bioenergetics and calcium buffering capacity in the basal ganglia correlates with motor deficits in a nonhuman primate model of aging

(2015) Jignesh D. Pandya et al.   NEUROBIOLOGY OF AGING

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

The restless brain: how intrinsic activity organizes brain function

(2015) M. E. Raichle   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

NH4+ triggers the release of astrocytic lactate via mitochondrial pyruvate shunting

(2015) Rodrigo Lerchundi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial function in the brain links anxiety with social subordination

(2015) Fiona Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How doth the little busy bee: unexpected metabolism

(2015) L. Felipe Barros et al.   TRENDS IN NEUROSCIENCES

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Glial β-Oxidation regulates Drosophila Energy Metabolism

(2015) Joachim G. Schulz et al.   Scientific Reports

Serotonin and the search for the anatomical substrate of aggression

(2015) Olga V Alekseyenko et al.   FLY

Neuronal glycogen synthesis contributes to physiological aging

(2014) Christopher Sinadinos et al.   AGING CELL

Aerobic Glycolysis in the Human Brain Is Associated with Development and Neotenous Gene Expression

(2014) Manu S. Goyal et al.   Cell Metabolism

Flies without Trehalose

(2014) Hiroko Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Exercise, Energy Intake, Glucose Homeostasis, and the Brain

(2014) H. van Praag et al.   JOURNAL OF NEUROSCIENCE

Glia ECM interactions are required to shape the Drosophila nervous system

(2014) Silke Meyer et al.   MECHANISMS OF DEVELOPMENT

A Systematic Nomenclature for the Insect Brain

(2014) Kei Ito et al.   NEURON

High Fat, Low Carbohydrate Diet Limit Fear and Aggression in Göttingen Minipigs

(2014) Annika Maria Juul Haagensen et al.   PLoS One

Socially responsive effects of brain oxidative metabolism on aggression

(2014) H. Li-Byarlay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuromolecular responses to social challenge: Common mechanisms across mouse, stickleback fish, and honey bee

(2014) Clare C. Rittschof et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling

(2014) Marko Brankatschk et al.   eLife

The Drosophila surface glia transcriptome: evolutionary conserved blood-brain barrier processes

(2014) Michael K. DeSalvo et al.   Frontiers in Neuroscience

Postembryonic lineages of the Drosophila brain: I. Development of the lineage-associated fiber tracts

(2013) Jennifer K. Lovick et al.   DEVELOPMENTAL BIOLOGY

Brain gene expression changes elicited by peripheralvitellogeninknockdown in the honey bee

(2013) M. M. Wheeler et al.   INSECT MOLECULAR BIOLOGY

Glial cell changes in epilepsy: Overview of the clinical problem and therapeutic opportunities

(2013) Jacqueline A. Hubbard et al.   NEUROCHEMISTRY INTERNATIONAL

Disturbance of aerobic metabolism accompanies neurobehavioral changes induced by nickel in mice

(2013) Min-Di He et al.   NEUROTOXICOLOGY

Mitochondria impact brain function and cognition

(2013) M. Picard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single dopaminergic neurons that modulate aggression in Drosophila

(2013) O. V. Alekseyenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system

(2013) W. W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

To Favor Survival Under Food Shortage, the Brain Disables Costly Memory

(2013) P.-Y. Placais et al.   SCIENCE

Sugar for the brain: the role of glucose in physiological and pathological brain function

(2013) Philipp Mergenthaler et al.   TRENDS IN NEUROSCIENCES

Genetics of Aggression

(2012) Robert R.H. Anholt et al.   Annual Review of Genetics

Understanding the Relationship Between Brain Gene Expression and Social Behavior: Lessons from the Honey Bee

(2012) Amro Zayed et al.   Annual Review of Genetics

A Fructose Receptor Functions as a Nutrient Sensor in the Drosophila Brain

(2012) Tetsuya Miyamoto et al.   CELL

Miniaturization of Nervous Systems and Neurons

(2012) Jeremy E. Niven et al.   CURRENT BIOLOGY

Deleterious effects of neuronal accumulation of glycogen in flies and mice

(2012) Jordi Duran et al.   EMBO Molecular Medicine

Size-related variation in protein abundance in the brain and abdominal tissue of bumble bee workers

(2012) F. Wolschin et al.   INSECT MOLECULAR BIOLOGY

Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing

(2012) C. N. Hall et al.   JOURNAL OF NEUROSCIENCE

Importance of glycolysis and oxidative phosphorylation in advanced melanoma

(2012) Jonhan Ho et al.   Molecular Cancer

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

The honeybee as a model for understanding the basis of cognition

(2012) Randolf Menzel   NATURE REVIEWS NEUROSCIENCE

Quantitative fMRI and oxidative neuroenergetics

(2012) Fahmeed Hyder et al.   NEUROIMAGE

High Sugar-Induced Insulin Resistance in Drosophila Relies on the Lipocalin Neural Lazarillo

(2012) Matthieu Y. Pasco et al.   PLoS One

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons

(2012) T. A. Wang et al.   SCIENCE

The ketogenic diet: metabolic influences on brain excitability and epilepsy

(2012) Andrew Lutas et al.   TRENDS IN NEUROSCIENCES

A GAL4-Driver Line Resource for Drosophila Neurobiology

(2012) Arnim Jenett et al.   Cell Reports

Lipoproteins in Drosophila melanogaster—Assembly, Function, and Influence on Tissue Lipid Composition

(2012) Wilhelm Palm et al.   PLoS Genetics

Calcium signaling around Mitochondria Associated Membranes (MAMs)

(2011) Simone Patergnani et al.   Cell Communication and Signaling

Morphological diversity and development of glia in Drosophila

(2011) Volker Hartenstein   GLIA

Properties of Ca2+Transport in Mitochondria ofDrosophila melanogaster

(2011) Sophia von Stockum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Traces of Drosophila Memory

(2011) Ronald L. Davis   NEURON

Modes of Metabolic Compensation during Mitochondrial Disease Using the Drosophila Model of ATP6 Dysfunction

(2011) Alicia M. Celotto et al.   PLoS One

Molecular evolutionary analyses of insect societies

(2011) B. J. Fischman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic regulation of cortical UP states

(2011) K. E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

(2010) Andrew Sauerbeck et al.   EXPERIMENTAL NEUROLOGY

Cellular and Subcellular Localization of Hexokinase, Glutamate Dehydrogenase, and Alanine Aminotransferase in the Honeybee Drone Retina

(2010) Anne-Lise Veuthey et al.   JOURNAL OF NEUROCHEMISTRY

Lipoprotein Particles Cross the Blood-Brain Barrier in Drosophila

(2010) M. Brankatschk et al.   JOURNAL OF NEUROSCIENCE

Drosophila Glial Glutamate Transporter Eaat1 Is Regulated by Fringe-Mediated Notch Signaling and Is Essential for Larval Locomotion

(2010) S. M. Stacey et al.   JOURNAL OF NEUROSCIENCE

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons

(2010) Jian Zou et al.   NEUROCHEMISTRY INTERNATIONAL

Metabolic Regulation of Neuronal Plasticity by the Energy Sensor AMPK

(2010) Wyatt B. Potter et al.   PLoS One

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

(2010) Andrei G. Vlassenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional aerobic glycolysis in the human brain

(2010) S. Neil Vaishnavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two views of brain function

(2010) Marcus E. Raichle   TRENDS IN COGNITIVE SCIENCES

Insect Fat Body: Energy, Metabolism, and Regulation

(2009) Estela L. Arrese et al.   Annual Review of Entomology

Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

(2009) Jeffrey M. Copeland et al.   CURRENT BIOLOGY

The trehalose transporter 1 gene sequence is conserved in insects and encodes proteins with different kinetic properties involved in trehalose import into peripheral tissues

(2009) Yasushi Kanamori et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Thein vivoneuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

(2009) Silvia Mangia et al.   JOURNAL OF NEUROCHEMISTRY

Evolutionary Conservation of Vertebrate Blood-Brain Barrier Chemoprotective Mechanisms in Drosophila

(2009) F. Mayer et al.   JOURNAL OF NEUROSCIENCE

Honey bee aggression supports a link between gene regulation and behavioral evolution

(2009) C. Alaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discrete molecular states in the brain accompany changing responses to a vocal signal

(2009) S. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of mitochondrial transport and localization in neurons

(2009) Andrew F. MacAskill et al.   TRENDS IN CELL BIOLOGY

Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila

(2008) T. Awasaki et al.   JOURNAL OF NEUROSCIENCE

Transient Hypoxia Stimulates Mitochondrial Biogenesis in Brain Subcortex by a Neuronal Nitric Oxide Synthase-Dependent Mechanism

(2008) D. R. Gutsaeva et al.   JOURNAL OF NEUROSCIENCE

Organization and Function of the Blood Brain Barrier in Drosophila

(2008) T. Stork et al.   JOURNAL OF NEUROSCIENCE

Reduction of DILP2 in Drosophila Triages a Metabolic Phenotype from Lifespan Revealing Redundancy and Compensation among DILPs

(2008) Susan Broughton et al.   PLoS One

Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies

(2008) S. A. Ament et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA