Predictive accuracy of combined genetic and environmental risk scores

Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes

(2016) Kashyap A. Patel et al.   DIABETES

Genomic prediction of coronary heart disease

(2016) Gad Abraham et al.   EUROPEAN HEART JOURNAL

Polygenic Epidemiology

(2016) Frank Dudbridge   GENETIC EPIDEMIOLOGY

Marginal role for 53 common genetic variants in cardiovascular disease prediction

(2016) Richard W Morris et al.   HEART

Developing and evaluating polygenic risk prediction models for stratified disease prevention

(2016) Nilanjan Chatterjee et al.   NATURE REVIEWS GENETICS

Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States

(2016) Paige Maas et al.   JAMA Oncology

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

(2015) Robert Maier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait

(2015) Luigi Palla et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic risk prediction of complex human disease and its clinical application

(2015) Gad Abraham et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

(2015) Jian Yang et al.   HUMAN MOLECULAR GENETICS

Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study

(2015) P. S. de Vries et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions

(2015) Joel L. Weissfeld et al.   Journal of Thoracic Oncology

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

(2015) Po-Ru Loh et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes

(2014) Philippa J. Talmud et al.   DIABETES

Limited Clinical Utility of a Genetic Risk Score for the Prediction of Fracture Risk in Elderly Subjects

(2014) Joel Eriksson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Combined Associations of Genetic and Environmental Risk Factors: Implications for Prevention of Breast Cancer

(2014) M. Garcia-Closas et al.   JNCI-Journal of the National Cancer Institute

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies

(2014) B. Verhulst et al.   PSYCHOLOGICAL MEDICINE

Genetic Risk Prediction and a 2-Stage Risk Screening Strategy for Coronary Heart Disease

(2013) Emmi Tikkanen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Net Reclassification Indices for Evaluating Risk Prediction Instruments

(2013) Kathleen F. Kerr et al.   EPIDEMIOLOGY

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

(2013) Nilanjan Chatterjee et al.   NATURE GENETICS

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts

(2012) Maria F. Hughes et al.   PLoS One

Comparison of Family History and SNPs for Predicting Risk of Complex Disease

(2012) Chuong B. Do et al.   PLoS Genetics

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk

(2011) Matthew A Simonson et al.   BMC Medical Genetics

Genetic risk prediction in complex disease

(2011) Luke Jostins et al.   HUMAN MOLECULAR GENETICS

Family History in Public Health Practice: A Genomic Tool for Disease Prevention and Health Promotion

(2010) Rodolfo Valdez et al.   Annual Review of Public Health

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

(2010) Cathy E Elks et al.   NATURE GENETICS

Performance of Common Genetic Variants in Breast-Cancer Risk Models

(2010) Sholom Wacholder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers

(2010) Michael J. Pencina et al.   STATISTICS IN MEDICINE

A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained

(2010) Hon-Cheong So et al.   PLoS Genetics

The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling

(2010) Naomi R. Wray et al.   PLoS Genetics

Predicting human height by Victorian and genomic methods

(2009) Yurii S Aulchenko et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

(2009) David M. Evans et al.   HUMAN MOLECULAR GENETICS

Putting Risk Prediction in Perspective: Relative Utility Curves

(2009) Stuart G. Baker   JNCI-Journal of the National Cancer Institute

Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes

(2009) David G. Clayton   PLoS Genetics

General Cardiovascular Risk Profile for Use in Primary Care

(2008) Ralph B. D’Agostino et al.   CIRCULATION

Polygenes, Risk Prediction, and Targeted Prevention of Breast Cancer

(2008) Paul D.P. Pharoah et al.   NEW ENGLAND JOURNAL OF MEDICINE