ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2

(2017) James B. Studd et al.   Nature Communications

Small genomic insertions form enhancers that misregulate oncogenes

(2017) Brian J. Abraham et al.   Nature Communications

Arid5a regulates naive CD4+T cell fate through selective stabilization of Stat3 mRNA

(2016) Kazuya Masuda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia

(2016) W S Liau et al.   LEUKEMIA

Activation of proto-oncogenes by disruption of chromosome neighborhoods

(2016) D. Hnisz et al.   SCIENCE

TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia

(2015) S H Tan et al.   LEUKEMIA

Super-enhancers delineate disease-associated regulatory nodes in T cells

(2015) Golnaz Vahedi et al.   NATURE

Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages

(2015) David Casero et al.   NATURE IMMUNOLOGY

Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions

(2015) Bin Guan et al.   NEOPLASIA

ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia

(2014) Mariana Emerenciano et al.   BMC CANCER

The emerging roles of ARID1A in tumor suppression

(2014) Ren-Chin Wu et al.   CANCER BIOLOGY & THERAPY

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

(2014) Daniel Herranz et al.   NATURE MEDICINE

An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

(2014) M. R. Mansour et al.   SCIENCE

Recent advances in the ARID family: focusing on roles in human cancer

(2014) Zhao Hong et al.   OncoTargets and Therapy

MYC Activation Is a Hallmark of Cancer Initiation and Maintenance

(2014) M. Gabay et al.   Cold Spring Harbor Perspectives in Medicine

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Intron 3 of the ARID5B gene: a hot spot for acute lymphoblastic leukemia susceptibility

(2013) Ángela Gutiérrez-Camino et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The TAL1 complex targets theFBXW7tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

(2013) Marc R. Mansour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Acute lymphoblastic leukaemia

(2013) Hiroto Inaba et al.   LANCET

The functional interactome landscape of the human histone deacetylase family

(2013) P. Joshi et al.   Molecular Systems Biology

MYC, Metabolism, Cell Growth, and Tumorigenesis

(2013) C. V. Dang   Cold Spring Harbor Perspectives in Medicine

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

(2012) Takaomi Sanda et al.   CANCER CELL

ARID5BGenetic Polymorphisms Contribute to Racial Disparities in the Incidence and Treatment Outcome of Childhood Acute Lymphoblastic Leukemia

(2012) Heng Xu et al.   JOURNAL OF CLINICAL ONCOLOGY

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling

(2012) Jun Seita et al.   PLoS One

ARID1A Mutations in Cancer: Another Epigenetic Tumor Suppressor?

(2012) Jennifer N. Wu et al.   Cancer Discovery

Mutation and Loss of Expression of ARID1A in Uterine Low-grade Endometrioid Carcinoma

(2011) Bin Guan et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B

(2011) Atsushi Baba et al.   NATURE CELL BIOLOGY

c-Myc Regulates Transcriptional Pause Release

(2010) Peter B. Rahl et al.   CELL

NKX3.1is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

(2010) Sophie Kusy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

(2009) Gang G. Wang et al.   NATURE

Germline genomic variants associated with childhood acute lymphoblastic leukemia

(2009) Lisa R Treviño et al.   NATURE GENETICS

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

(2009) Elli Papaemmanuil et al.   NATURE GENETICS

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

(2008) P. Van Vlierberghe et al.   BLOOD

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

(2008) J.-R. Landry et al.   BLOOD

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET