Silencing of HIV-1 by AgoshRNA molecules

The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site

(2016) Elena Herrera-Carrillo et al.   NUCLEIC ACIDS RESEARCH

Toward optimization of AgoshRNA moleculesthat use a non-canonical RNAi pathway: Variations in the top and bottom base pairs

(2015) Elena Herrera-Carrillo et al.   RNA Biology

Deep Sequence Analysis of AgoshRNA Processing Reveals 3’ A Addition and Trimming

(2015) Alex Harwig et al.   Molecular Therapy-Nucleic Acids

Molecular Properties, Functional Mechanisms, and Applications of Sliced siRNA

(2015) Guihua Sun et al.   Molecular Therapy-Nucleic Acids

Towards improved shRNA and miRNA reagents as inhibitors of HIV1 replication

(2014) Ben Berkhout et al.   Future Microbiology

Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity

(2014) Elena Herrera-Carrillo et al.   RNA

Pol III Promoters to Express Small RNAs: Delineation of Transcription Initiation

(2014) Hongming Ma et al.   Molecular Therapy-Nucleic Acids

Designing Ago2-specific siRNA/shRNA to Avoid Competition with Endogenous miRNAs

(2014) Hongming Ma et al.   Molecular Therapy-Nucleic Acids

Dicer-independent processing of short hairpin RNAs

(2013) Y. P. Liu et al.   NUCLEIC ACIDS RESEARCH

Poly(A)-Specific Ribonuclease Mediates 3′-End Trimming of Argonaute2-Cleaved Precursor MicroRNAs

(2013) Mayuko Yoda et al.   Cell Reports

Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1

(2013) Mireille Centlivre et al.   Molecular Therapy-Nucleic Acids

SHAPE-directed Discovery of Potent shRNA Inhibitors of HIV-1

(2012) Justin T Low et al.   MOLECULAR THERAPY

Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing

(2012) Anne Dallas et al.   NUCLEIC ACIDS RESEARCH

microRNAs associated with the different human Argonaute proteins

(2012) A. Dueck et al.   NUCLEIC ACIDS RESEARCH

A competitive cell growth assay for the detection of subtle effects of gene transduction on cell proliferation

(2011) J J M Eekels et al.   GENE THERAPY

Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

(2011) S. Petri et al.   RNA

Absence of DICER in Monocytes and Its Regulation by HIV-1

(2010) William Coley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Posttranscriptional Regulation of MicroRNA Biogenesis in Animals

(2010) Haruhiko Siomi et al.   MOLECULAR CELL

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

(2010) J.-S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies

(2010) Y. P. Liu et al.   RNA

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

Toward a Durable Anti-HIV Gene Therapy Based on RNA Interference

(2009) Ben Berkhout   Annals of the New York Academy of Sciences

Sequence features associated with microRNA strand selection in humans and flies

(2009) Hai Hu et al.   BMC GENOMICS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 ‘Slicer’ independent and can be mediated by Ago1

(2009) Timothy A. Vickers et al.   NUCLEIC ACIDS RESEARCH

Minimal-length short hairpin RNAs: The relationship of structure and RNAi activity

(2009) Q. Ge et al.   RNA

Importance of Translation and Nonnucleolytic Ago Proteins for On-Target RNA Interference

(2008) Ligang Wu et al.   CURRENT BIOLOGY