4.2 Article

C-Section Prevalence Among Obese Mothers and Neonatal Hypoglycemia: a Cohort Analysis of the Department of Gynecology and Obstetrics of the University of Lubeck

Journal

GEBURTSHILFE UND FRAUENHEILKUNDE
Volume 77, Issue 5, Pages 487-494

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0043-108763

Keywords

adiposity; obesity; mode of delivery; pregnancy; neonatal outcome

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Introduction Data from the World Health Organization ( WHO) demonstrates an increasing prevalence of obesity in Western countries. This study investigates the influence of obesity on the mode of delivery and the occurrence of hypoglycemia in newborns. Materials and Methods A retrospective analysis of all deliveries at the Department of Gynecology and Obstetrics of the University of Lubeck, Germany was conducted over a period of eleven years with the primary outcome as non-elective Csections and hypoglycemia of newborns from obese mothers. Patients were divided into six subgroups according to WHO weight classifications as follows: control group body mass index ( BMI) 18.5-24.9 kg/m(2), n = 7712; general obesity BMI = 25 kg/m(2), n = 4227; overweight BMI 25-29.9 kg/m(2), n = 2628; obesity I degrees BMI 30-34.9 kg/m(2), n = 1017; obesity II degrees BMI 35-39.9 kg/m(2), n = 370; obesity III degrees BMI = 40 kg/m(2), n = 212. Results Analysis of the primary outcome shows an increased incidence of non- elective C-sections with an elevated BMI ( general obesity vs. control group: 20.5 vs. 15.9%, p < 0.001; OR 1.3; 95% CI 1.2-1.4) and elevated rates of neonatal hypoglycemia in newborns of obese mothers ( general obesity vs. control group: 0.6 vs. 0.3%, p < 0.05; OR 1.8; 95% CI 1.0-3.0). Conclusions Obesity is an essential obstetric risk factor. Obese women face an increased risk of non- elective C-sections, and newborns of obese mothers suffer from elevated rates of hypoglycemia.

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