Cutaneous wound biofilm and the potential for electrical stimulation in management of the microbiome

Cathodic Voltage-controlled Electrical Stimulation Plus Prolonged Vancomycin Reduce Bacterial Burden of a Titanium Implant-associated Infection in a Rodent Model

(2016) Scott R. Nodzo et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Antibiofilm Activity of Electrical Current in a Catheter Model

(2015) Paul Voegele et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Assessment of Electric Currents Increasing the Effectiveness of Vancomycin AgainstStaphylococcus epidermidisBiofilms

(2015) Peter A. Haddad et al.   ARTIFICIAL ORGANS

Cathodic voltage-controlled electrical stimulation of titanium implants as treatment for methicillin-resistant Staphylococcus aureus periprosthetic infections

(2015) Mark T. Ehrensberger et al.   BIOMATERIALS

The intersection of microbiome and host at the skin interface: genomic- and metagenomic-based insights

(2015) Elizabeth A. Grice   GENOME RESEARCH

Inhibitory effect of direct electric field and HA-ZnO composites onS. aureusbiofilm formation

(2015) Sunil Kumar Boda et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

The Cutaneous Microbiome in Outpatients Presenting With Acute Skin Abscesses

(2015) James M. Horton et al.   JOURNAL OF INFECTIOUS DISEASES

Electrical Stimulation Enhances Epidermal Proliferation in Human Cutaneous Wounds by Modulating p53–SIVA1 Interaction

(2015) Anil Sebastian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Polarized currents inhibit in vitro growth of bacteria colonizing cutaneous ulcers

(2015) Rosana Caetano Gomes et al.   WOUND REPAIR AND REGENERATION

Analysis of the chronic wound microbiota of 2,963 patients by 16S rDNA pyrosequencing

(2015) Randall D. Wolcott et al.   WOUND REPAIR AND REGENERATION

Electrochemical scaffold generates localized, low concentration of hydrogen peroxide that inhibits bacterial pathogens and biofilms

(2015) Sujala T. Sultana et al.   Scientific Reports

Next-Generation Sequencing: A Review of Technologies and Tools for Wound Microbiome Research

(2015) Brendan P. Hodkinson et al.   Advances in Wound Care

Biofilms and Wounds: An Overview of the Evidence

(2015) Steven L. Percival et al.   Advances in Wound Care

Silver-Zinc Redox-Coupled Electroceutical Wound Dressing Disrupts Bacterial Biofilm

(2015) Jaideep Banerjee et al.   PLoS One

Angiogenesis Is Induced and Wound Size Is Reduced by Electrical Stimulation in an Acute Wound Healing Model in Human Skin

(2015) Sara Ud-Din et al.   PLoS One

Review article: fungal microbiota and digestive diseases

(2014) Z. K. Wang et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mechanistic insights into response of Staphylococcus aureus to bioelectric effect on polypyrrole/chitosan film

(2014) Jieyu Zhang et al.   BIOMATERIALS

Biogeography and individuality shape function in the human skin metagenome

(2014) Julia Oh et al.   NATURE

A study of biofilm-based wound management in subjects with critical limb ischaemia

(2014) R.D. Wolcott et al.   Journal of Wound Care

An improved dual-indexing approach for multiplexed 16S rRNA gene sequencing on the Illumina MiSeq platform

(2014) Douglas W Fadrosh et al.   Microbiome

The evolution of antibiotic susceptibility and resistance during the formation of Escherichia coli biofilms in the absence of antibiotics

(2013) Jabus G Tyerman et al.   BMC EVOLUTIONARY BIOLOGY

Direct Electric Current Treatment under Physiologic Saline Conditions Kills Staphylococcus epidermidis Biofilms via Electrolytic Generation of Hypochlorous Acid

(2013) Elizabeth L. Sandvik et al.   PLoS One

Life on Human Surfaces: Skin Metagenomics

(2013) Alban Mathieu et al.   PLoS One

Assessing the Fecal Microbiota: An Optimized Ion Torrent 16S rRNA Gene-Based Analysis Protocol

(2013) Christian Milani et al.   PLoS One

Bacterial Inhibition by Electrical Stimulation

(2013) Mohammad Reza Asadi et al.   Advances in Wound Care

Vascular Endothelial Growth Factor Release Following Electrical Stimulation in Human Subjects

(2013) Richard Eloin Liebano et al.   Advances in Wound Care

Biophysical Technologies for Management of Wound Bioburden

(2013) Holly Korzendorfer et al.   Advances in Wound Care

Harnessing the Electric Spark of Life to Cure Skin Wounds

(2013) Cristina Martin-Granados et al.   Advances in Wound Care

Clinical identification of bacteria in human chronic wound infections: culturing vs. 16S ribosomal DNA sequencing

(2012) Daniel D Rhoads et al.   BMC INFECTIOUS DISEASES

Capacitive Coupling Reduces Instrumentation-related Infection in Rabbit Spines: A Pilot Study

(2012) Mohit Gilotra et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The Neuropathic Diabetic Foot Ulcer Microbiome Is Associated With Clinical Factors

(2012) S. E. Gardner et al.   DIABETES

Electrical stimulation increases blood flow and haemoglobin levels in acute cutaneous wounds without affecting wound closure time: evidenced by non-invasive assessment of temporal biopsy wounds in human volunteers

(2012) Sara Ud-Din et al.   EXPERIMENTAL DERMATOLOGY

Comparison of Culture and Molecular Identification of Bacteria in Chronic Wounds

(2012) Daniel D. Rhoads et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The microbiome in wound repair and tissue fibrosis

(2012) Brittan S Scales et al.   JOURNAL OF PATHOLOGY

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Human Skin Microbiota: High Diversity of DNA Viruses Identified on the Human Skin by High Throughput Sequencing

(2012) Vincent Foulongne et al.   PLoS One

Extending the TIME concept: what have we learned in the past 10 years?*

(2012) David J Leaper et al.   International Wound Journal

Decreased Staphylococcus aureus biofilm growth on anodized nanotubular titanium and the effect of electrical stimulation

(2011) Batur Ercan et al.   Acta Biomaterialia

Characterization of Bacterial Communities in Venous Insufficiency Wounds by Use of Conventional Culture and Molecular Diagnostic Methods

(2011) Marie S. Tuttle et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Discussion: The Role of Biofilms: Are We Hitting the Right Target?

(2011) J. William Costerton et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Acceleration of cutaneous healing by electrical stimulation: Degenerate electrical waveform down-regulates inflammation, up-regulates angiogenesis and advances remodeling in temporal punch biopsies in a human volunteer study

(2011) Anil Sebastian et al.   WOUND REPAIR AND REGENERATION

The importance of a multifaceted approach to characterizing the microbial flora of chronic wounds

(2011) Anne Han et al.   WOUND REPAIR AND REGENERATION

Microbiology of the skin and the role of biofilms in infection

(2011) Steven L Percival et al.   International Wound Journal

Evaluation of the bacterial diversity of Pressure ulcers using bTEFAP pyrosequencing

(2010) Drake M Smith et al.   BMC Medical Genomics

Real-time PCR assays compared to culture-based approaches for identification of aerobic bacteria in chronic wounds

(2010) J.H. Melendez et al.   CLINICAL MICROBIOLOGY AND INFECTION

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities

(2010) K. E. Hill et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Macroscale spatial variation in chronic wound microbiota: A cross-sectional study

(2010) Lance B. Price et al.   WOUND REPAIR AND REGENERATION

The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods

(2010) Trine R. Thomsen et al.   WOUND REPAIR AND REGENERATION

Biofilms and bacterial imbalances in chronic wounds: anti-Koch

(2010) Steven L Percival et al.   International Wound Journal

The Electricidal Effect Is Active in an Experimental Model of Staphylococcus epidermidis Chronic Foreign Body Osteomyelitis

(2009) J. L. Del Pozo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and Titanium amplicon pyrosequencing and metagenomic approaches

(2009) Randall D Wolcott et al.   BMC MICROBIOLOGY

The NIH Human Microbiome Project

(2009) et al.   GENOME RESEARCH

Community Analysis of Chronic Wound Bacteria Using 16S rRNA Gene-Based Pyrosequencing: Impact of Diabetes and Antibiotics on Chronic Wound Microbiota

(2009) Lance B. Price et al.   PLoS One

Role of Mutation in Pseudomonas aeruginosa Biofilm Development

(2009) Tim C. R. Conibear et al.   PLoS One

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Microbial diversity in chronic open wounds

(2009) Daniel N. Frank et al.   WOUND REPAIR AND REGENERATION

Effect of Electrical Current on the Activities of Antimicrobial Agents against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis Biofilms

(2008) J. L. del Pozo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Wound Bioburden and Infection-Related Complications in Diabetic Foot Ulcers

(2008) S. E. Gardner et al.   Biological Research for Nursing

Survey of bacterial diversity in chronic wounds using Pyrosequencing, DGGE, and full ribosome shotgun sequencing

(2008) Scot E Dowd et al.   BMC MICROBIOLOGY

Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases

(2008) Daniel A. Peterson et al.   Cell Host & Microbe

A diversity profile of the human skin microbiota

(2008) E. A. Grice et al.   GENOME RESEARCH

Metagenomics

(2008) Philip Hugenholtz et al.   NATURE

Polymicrobial Nature of Chronic Diabetic Foot Ulcer Biofilm Infections Determined Using Bacterial Tag Encoded FLX Amplicon Pyrosequencing (bTEFAP)

(2008) Scot E. Dowd et al.   PLoS One

Biofilms in chronic wounds

(2008) Garth A. James et al.   WOUND REPAIR AND REGENERATION

Effect of electric currents on bacterial detachment and inactivation

(2007) Seok Hoon Hong et al.   BIOTECHNOLOGY AND BIOENGINEERING

Why chronic wounds will not heal: a novel hypothesis

(2007) Thomas Bjarnsholt et al.   WOUND REPAIR AND REGENERATION