Journal
CORNEA
Volume 34, Issue 1, Pages 87-89Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/ICO.0000000000000296
Keywords
Aloe vera; ocular surface squamous neoplasia; chemotherapy
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Funding
- NIH Center [P30EY014801]
- RPB
- Department of Defense (DOD) [W81XWH-09-1-0675]
- Ronald and Alicia Lepke Grant
- Lee and Claire Hager Grant
- Jimmy and Gaye Bryan Grant
- Richard Azar Family Grant
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Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment. Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment. Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years. Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.
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