Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals

Title
Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals
Authors
Keywords
2,6-dibromohydroquinone, Cu(II), DNA strand breakage 8-oxo-7,8-dihydro-2'-deoxyguanosine formation, Site-specific mechanism, Hydroxyl radical
Journal
FREE RADICAL BIOLOGY AND MEDICINE
Volume 104, Issue -, Pages 54-63
Publisher
Elsevier BV
Online
2017-01-06
DOI
10.1016/j.freeradbiomed.2016.12.050

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