Article
Geriatrics & Gerontology
Zhen Zhou, Joanne Ryan, Mark R. Nelson, Robyn L. Woods, Suzanne G. Orchard, Chao Zhu, Julia F. M. Gilmartin-Thomas, Michelle A. Fravel, Alice J. Owen, Anne M. Murray, Sara E. Espinoza, Michael E. Ernst
Summary: This study aims to determine the association between allopurinol use and persistent physical disability and frailty in older gout patients. The results showed that allopurinol use was associated with a reduced risk of persistent physical disability, but not associated with the risk of frailty.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Gerontology
Dan Marciniak, Neil B. Alexander, Geoffrey J. Hoffman
Summary: The study found that American veterans, especially as they age, face an increased risk of noninjurious falls compared to nonveterans. However, veterans reported fewer fall-related injuries. Engaging in regular physical activity may be particularly effective for veterans in reducing the risks associated with falls and fall injuries as they age.
JOURNAL OF APPLIED GERONTOLOGY
(2021)
Article
Environmental Sciences
Esther Garcia-Esquinas, Maria Tellez-Plaza, Roberto Pastor-Barriuso, Rosario Ortola, Pablo Olmedo, Fernando Gil, Esther Lopez-Garcia, Ana Navas-Acien, Fernando Rodriguez-Artalejo
Summary: The study found that blood cadmium levels were associated with physical performance, lower-extremity performance, grip strength, mobility limitations, frailty, and instrumental activities of daily living disability in older adults. The associations were consistent in both cross-sectional and longitudinal analyses, supporting the role of cadmium as a risk factor for physical function impairments in the elderly.
ENVIRONMENTAL POLLUTION
(2021)
Article
Geriatrics & Gerontology
Katie J. J. McMenamin, Tamara B. B. Harris, Joshua F. F. Baker
Summary: This study aimed to investigate the association between variability in body mass index (BMI) and declines in physical functioning and incident disability among older adults. The results showed that participants with higher BMI variability were more likely to experience weight and fat loss, declines in physical performance, and had higher rates of incident disability, independent of net BMI change.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Substance Abuse
Sarah Larney, Nicola R. Jones, Matthew Hickman, Suzanne Nielsen, Robert Ali, Louisa Degenhardt
Summary: This retrospective observational cohort study examines the association between opioid agonist treatment (OAT) and overdose death among different age groups in New South Wales, Australia. The findings suggest that OAT is associated with a lower risk of opioid overdose death compared to time out of treatment. Buprenorphine may provide greater protection against overdose death than methadone, particularly in older individuals and those with circulatory or respiratory diseases.
Article
Public, Environmental & Occupational Health
Sanae Matsuyama, Yoshitaka Murakami, Yukai Lu, Yumi Sugawara, Ichiro Tsuji
Summary: An increase in time spent walking is associated with longer DFLE in Japanese older people. Encouraging simple physical activity such as walking at the population level could increase life-years lived in good health.
PREVENTIVE MEDICINE
(2022)
Article
Education, Special
R. Hussain, S. Wark, M. P. Janicki, T. Parmenter, M. Knox, H. Tabatabaei-Jafari
Summary: The study examined the mental health of 391 community-dwelling adults with intellectual disability aged 60 and older in two East Coast Australian states. It found that older adults with ID have similar mental health disorders as other aging individuals, with employment status being a clear predictor. The study highlighted the importance of greater awareness among health professionals and care staff to provide tailored support for older adults with ID to reduce the burden of mental ill-health.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
E. Garcia-Esquinas, M. Carrasco-Rios, R. Ortola, M. Sotos Prieto, B. Perez-Gomez, E. Gutierrez-Gonzalez, J. R. Banegas, R. Queipo, P. Olmedo, F. Gil, M. Tellez-Plaza, A. Navas-Acien, R. Pastor-Barriuso, F. Rodriguez-Artalejo
Summary: The study found that selenium levels in the blood were inversely associated with physical function limitations in older adults, with a potentially progressive trend. In the longitudinal study in Spain, increasing baseline selenium levels were associated with improvement in certain physical functions.
Article
Public, Environmental & Occupational Health
Kimiko Tomioka, Midori Shima, Keigo Saeki
Summary: This study investigated the relationship between leisure activities (LA) in old age and incident disability, and found age and gender differences in these relationships. Regular physical and cognitive LA were associated with a lower risk of incident disability among community-dwelling older adults. Specifically, frequent physical activity was found to be effective in preventing long-term care, especially for the young-old age group.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2022)
Article
Genetics & Heredity
Sanjida Ahmed, Ramzan Tahir, Umbreen Akhtar, Mark Faiz
Summary: The study evaluated the impact of pharmacogenomic profiling on prescription changes for workers with mental health-related disabilities. The results showed that pharmacogenomics-based prescription changes significantly improved medication effectiveness in patients, contributing to better treatment outcomes.
FRONTIERS IN GENETICS
(2021)
Article
Geriatrics & Gerontology
Yen-Kuang Lin, Chen-Yueh Chen, Denise Shuk Ting Cheung, Jed Montayre, Chen-Yin Lee, Mu-Hsing Ho
Summary: This study identified four trajectories of physical activity patterns in older people over a 20-year period, and found that physical activity patterns are related to frailty. Risk factors for frailty such as older age, gender, poor oral health, diabetes, chronic kidney disease, and depressive symptoms were also identified.
Article
Geriatrics & Gerontology
Henna Saari, Olli-Pekka Ryynanen, Eija Lonnroos, Pekka Kekolahti, Pekka Mantyselka, Simo Kokko
Summary: This study aimed to investigate the outcomes of primary care physician-led community hospitals for older people in Finland and the role of active rehabilitation during hospitalization. The analysis revealed that daily rehabilitation was associated with successful discharge to home for older patients, highlighting the importance of community hospitals in acute care and rehabilitation for the aging population.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Multidisciplinary Sciences
Rossella Martarelli, Georgia Casanova, Giovanni Lamura
Summary: This study aims to examine the impact of poor health on older people's economic conditions and their families, as well as related concepts such as socio-economic deprivation. The research utilizes a three-step approach to map the main concepts and identify research gaps, in order to provide guidance for future policies addressing the double burden of poverty and ill health.
Article
Public, Environmental & Occupational Health
Laia Maynou, Andrew Street, Anna Garcia-Altes
Summary: This study aimed to identify factors that explain healthcare costs and found that age and proximity to death are not predictors of higher costs. Morbidity status, especially neoplasms and multiple long term conditions, are the most important factors associated with high healthcare costs.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Geriatrics & Gerontology
Barbara Senesi, Camilla Prete, Giacomo Siri, Alessandra Pinna, Angela Giorgeschi, Nicola Veronese, Roberto Sulpasso, Carlo Sabba, Alberto Pilotto
Summary: The multidimensional prognostic index (MPI) is highly effective in identifying frail older individuals who need to apply for social benefits, including Attendance Allowance (AA) indemnity, Carer's Leave (Law 104), and/or Parking Card for people with disabilities. It is a valuable tool for predicting the release of civil invalidity benefits.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)