Article
Fisheries
Songhuan Chang, Jiali Wang, Chuanju Dong, Yanliang Jiang
Summary: Common carp is an important freshwater farmed fish species worldwide and is susceptible to pathogen Aeromonas hydrophila. In this study, 16S rDNA sequencing was used to analyze the composition and biodiversity of intestinal microbiota in common carp following A. hydrophila infection. The results showed that the diversity and richness of microbiota decreased after infection, and the relative abundance of specific genera was significantly altered. Further analysis revealed potential correlations between certain genera and host resistance against pathogens. This study contributes to our understanding of the underlying mechanisms of intestinal microbial community in resisting pathogens and may provide strategies for disease control in aquaculture.
AQUACULTURE REPORTS
(2023)
Article
Fisheries
Lan Zhang, Lei Wang, Jintai Huang, Zhan Jin, Junxiang Guan, Hang Yu, Meng Zhang, Miao Yu, Hongxia Jiang, Zhigang Qiao
Summary: In this study, the effects of A. hydrophila infection on the intestinal microbiota, transcriptome, and metabolome of Cyprinus carpio were investigated. The results showed significant changes in the intestinal microbiota, with a decrease in beneficial bacteria and an increase in pathogenic bacteria. The transcriptome analysis revealed altered expression of immune-related genes, and the metabolomic analysis indicated disturbances in amino acid metabolism. This study provides insight into the underlying mechanisms of the intestinal microbiota, immunity, and metabolism involved in the response of carp to A. hydrophila infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Immunology
Di Wu, Ze Fan, Jinnan Li, Yuanyuan Zhang, Chang'an Wang, Qiyou Xu, Liansheng Wang
Summary: The study found that α-ketoglutarate can improve the survival rate of mirror carp after infection, enhance intestinal enzyme immunosuppressive activities and antioxidant capacities, alleviate intestinal inflammation, and promote immune responses and barrier functions.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Yanjing Zhao, Jie Zhang, Dan Qiao, Feng Gao, Xinyu Jiang, Xianliang Zhao, Libo Hou, Hao Li, Li Li, Xianghui Kong
Summary: In this study, the molecular and structural characteristics of CcGSDMEa-like were analyzed, and its role in the inflammatory response against Aeromonas hydrophila in fish was studied. The results showed that CcGSDMEa-like could regulate the content of bacteria in fish through mediating the expression and secretion of CcIL-1 beta.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Immunology
Akshaya Radhakrishnan, D. S. Prabakaran, Thiyagarajan Ramesh, Ramalingam Sakthivel, Kavikumar Ramasamy, Hyo-Shim Han, Sivakamavalli Jeyachandran
Summary: This study aimed to enhance innate immune responses in juvenile common carp by administering heat-killed Aeromonas hydrophila through bio-encapsulation in Artemia salina. The results showed that bio-encapsulated oral administration of antigens can promote innate immunity in juvenile-stage fishes. The immune responses in the treatment groups were substantially induced or enhanced compared to the control group.
Article
Fisheries
Xianliang Zhao, Xin Liu, Yunpeng Yang, Yifan Lu, Lei Zhu, Li Li, Xianghui Kong
Summary: This study investigated the metabolic profiling of susceptible and resistant Cyprinus carpio upon Aeromonas hydrophila infection using NMR metabolomics approach. It was found that exogenous myo-inositol can enhance the host's ability to fight bacterial infection and alleviate inflammatory response and oxidative damage.
Article
Immunology
Qingjiang Mu, Zhaoran Dong, Weiguang Kong, Xinyou Wang, Jiaqian Yu, Wei Ji, Jianguo Su, Zhen Xu
Summary: This study investigates the immune response of gut mucosal IgM during bacterial invasion using a common carp model. The results show that IgM(+) B cells are strongly induced in the gut and head kidney upon bacterial infection, and bacteria-specific IgM responses are detected in high levels in both the gut mucus and serum. These findings reveal the crucial role of IgM in the defense mechanisms of the gut against bacterial invasion.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Minghui Yu, Songhuan Chang, Jian Xu, Hanyuan Zhang, Yanliang Jiang
Summary: This study identified a set of endosialin family genes in the common carp genome and studied their expression patterns and immune response to Aeromonas hydrophila infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Shuang Wang, Mei Li, Yu Jiang, Chang Sun, Gongqing Wu, Chengyong Yang, Wenli Liu, Yufang Pan
Summary: This study investigated the differential gene expression and pathway enrichment in the spleen of koi carp infected with A. hydrophila. The results showed that 252 differentially expressed genes were identified, and they were involved in 133 pathways, including immune defense and inflammatory response-related pathways. qPCR validation confirmed the expression levels of selected differentially expressed genes. This study provided theoretical support for future drug development during A. hydrophila infection of koi carp.
MOLECULAR IMMUNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Sekar Jinendiran, Ramanathan Archana, Ramamoorthy Sathishkumar, Ramachandran Kannan, Gopal Selvakumar, Natesan Sivakumar
Summary: The study showed that dietary supplementation of Aeromonas veronii V03 had significant positive effects on growth and immune response in Cyprinus carpio, as well as increasing resistance to Aeromonas hydrophila infection. The probiotic feed was found to improve various immune parameters and gene expression in the fish's lymphoid organs, leading to higher survival rates against the pathogen.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Fisheries
Sang Wha Kim, Hyoun Joong Kim, Sang Guen Kim, Jun Kwon, Sung Bin Lee, Won Joon Jung, Young Min Lee, Su Jin Jo, Sib Sankar Giri, Seok Hyun Yoon, Seon Ho Kim, Chan Mo Kim, Cheng Chi, Se Chang Park
Summary: This study investigates the bactericidal efficacy of plasma-activated water induced by non-thermal plasma and its adverse effects on koi fish. The results show that non-thermal plasma can effectively sterilize water without causing significant physiological damage to the fish. This research provides promising prospects for water purification in aquaculture practice.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Morteza Yousefi, Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Ghasem Rashidian, Hien Van Doan
Summary: The study found that dietary supplementation with 200 mg/kg marjoram extract is recommended for common carp, as it enhances growth performance, antioxidant capacity, and immune system, thereby improving survival rate during Aeromonas septicemia.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Heba H. Mahboub, Caterina Faggio, Basma M. Hendam, Samah Attia Algharib, Mohamed Alkafafy, Marwa Abo Hashem, Yasmina K. Mahmoud, Tarek Khamis, Heba M. Abdel-Ghany, Shimaa R. Masoud, Afaf N. Abdel Rahman
Summary: This study investigates the effects of incorporating apricot kernel powder (PAKP) into the diet of Common carp on fish growth, digestion, intestinal morphology, immunity, antioxidant capacity, and antibacterial role against Aeromonas veronii infection. The results suggest that PAKP inclusion in the diet improves growth, digestion, immunity, and antioxidant capacity in a dose-dependent manner, while also protecting against bacterial infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Morteza Yousefi, Seyyed Morteza Hoseini, Afaf N. Abdel Rahman, Yury Anatolyevich Vatnikov, Evgeny Vladimirovich Kulikov, Elena Valentinovna Kharlitskaya, Sergey Borisovich Seleznev
Summary: This study examines the effects of dietary limonene treatment on growth performance, immune response, and disease resistance in common carp. The results indicate that adding 200 mg/kg limonene to the diet improves feed efficiency, boosts innate immunity, and increases resistance against Aeromonas hydrophila.
Article
Fisheries
Huaping Zhao, Hui Wang, Rongrong Liu, Yaxin Liang, Kaimin Li, Shijuan Shan, Liguo An, Guiwen Yang, Hua Li
Summary: In this study, the activation and function of CcNLRP1 inflammasome were investigated in common carp, and a specific ligand for CcNLRP1 activation was identified. The study provides insights into the role of CcNLRP1 in innate immune defense.
FISH & SHELLFISH IMMUNOLOGY
(2022)
