Article
Biochemistry & Molecular Biology
Wanjing Zou, Jingwei Gu, Jianna Li, Yuanfang Wang, Shiguo Chen
Summary: The study successfully synthesized IQAS and ISB derivatives and systematically investigated the effects of their substitution degree, carbon chain length, and content ratio on water solubility, antibacterial activity, and cytotoxicity of CS derivatives, suggesting that the properties of CS derivatives can be tailored by adjusting the amount of grafted antibacterial agents.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Lin Wang, Meihua Xin, Mingchun Li, Wenfeng Liu, Yangfan Mao
Summary: In this study, three new chitosan quaternary phosphonium compounds were synthesized and characterized. Their antibacterial activities against Escherichia coli and Staphylococcus aureus, as well as their antibiofilm activities, were investigated. The results showed that the chitosan quaternary phosphonium salts exhibited stronger antibacterial and antibiofilm activities compared to chitosan quaternary ammonium salt.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Can Cao, Zongkai Lin, Xiaochen Liu, Yanyan Jia, Eduardo Saiz, Stephan E. Wolf, Hanoch Daniel Wagner, Lei Jiang, Qunfeng Cheng
Summary: Coating Bombyx mori silks with a thin layer of reduced graphene oxide (rGO) has been shown to significantly increase their tensile strength and toughness. This bioinspired approach provides a universal and facile strategy for functionalizing natural fibers.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Medicinal
Jingjing Zhang, Wenqiang Tan, Qing Li, Xiaorui Liu, Zhanyong Guo
Summary: The study successfully obtained a series of novel CTMCSG hydrogel films with good water stability, thermal stability, drug release capacity, and antibacterial property. The properties of the hydrogel films improved with an increase in the amount of the cross-linking agent, resulting in reduced water vapor permeability.
Article
Materials Science, Multidisciplinary
Chao Zhang, Zhicheng Zhou, Xinru Wang, Jingjing Liu, Jing Sun, Lingren Wang, Wei Ye, Changjiang Pan
Summary: In this study, a regenerated silk fibroin (RSF) and chitosan quaternary ammonium salt (HACC)/heparin (Hep) multilayer coating was successfully fabricated on a magnesium (Mg) alloy surface. The multilayer coating exhibited improved corrosion resistance, reduced degradation rate, excellent biocompatibility, and antibacterial activity, highlighting its potential for medical applications on Mg-based substrates.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Dhruval K. Joshi, Frank Betancourt, Alyssa McAdorey, Ravi Shekar Yalagala, Andy Poupon, Hongbin Yan
Summary: N,N,N-trimethyl-2(4,4-difluoro-4-bora-3a,4a-diaza-s-indacen-8-yl)ethylammonium iodide (BODIPY quaternary ammonium 17) was successfully synthesized using 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene as starting material. Although less stable than Rose Bengal, this BODIPY ammonium showed superior photosensitizing efficiency and faster photodegradation rate. It also exhibited antibacterial activity against Bacillus subtilis when exposed to light.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Agricultural Engineering
Yiran Li, Hui Zhao, Tao Li, Dawei Shang, Limin Wu, Ning Guan, Shaohua Wu
Summary: A novel two-step modification strategy was used to functionalize commonly used cotton fibers into highly effective antibacterial fibers. These fibers demonstrated high antibacterial sustainability and durability, while maintaining low cost. By blending only 10% of these functionalized fibers into nonwoven fabrics, strong antibacterial efficiency was achieved without compromising cytocompatibility. This study presents a simple and cost-effective technique for fabricating advanced functional textiles that can be widely applied in daily lives.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biophysics
Denise Molinnus, Aleksander Drinic, Heiko Iken, Nadja Kroeger, Max Zinser, Ralf Smeets, Marius Koepf, Alexander Kopp, Michael J. Schoening
Summary: In modern times, there is a growing need for flexible and biocompatible sensors for in-vivo and epidermal applications. One promising approach is the use of biological polymers, which offer new opportunities for flexible biosensor devices due to their high biocompatibility and adjustable biodegradability. It is important to consider factors such as stability, mechanical properties, and cross-sensitivity in the development of such sensors.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Materials Science, Paper & Wood
Peixuan Wu, Yunxi Cui, Zhicheng Sun, Meijuan Cao, Yuanyuan Liu, Kun Fu, Yang Zhou
Summary: In this study, an antibacterial sodium alginate derivative was successfully developed through covalent coupling of organosilane quaternary ammonium salt with sodium alginate. The material exhibited high antibacterial efficiency against Staphylococcus aureus and Escherichia coli, reaching up to 99.6% and 99.3%, respectively. Additionally, the material demonstrated good biocompatibility and potential application in the fabrication of sodium alginate beads.
Article
Biochemistry & Molecular Biology
Liangli Yang, Yue Zhao, Quan Gan, Dan Liang, Rui Shu, Song Jiang, Ruiping Xie, Yan Meng
Summary: In this study, a novel beta-fructofuranosidase gene, BmSuc1, was cloned and identified for the first time in the silkworm. The results showed that BmSUC1 plays a role in the synthesis of silk protein in the silk gland, affecting the sericin content and mechanical properties of silk fibers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Applied
Qingyan Pan, Chuang Zhou, Ziming Yang, Zuyu He, Chao Wang, Yunhao Liu, Shuhui Song, Hui Gu, Keqian Hong, Lijuan Yu, Yunhui Qu, Puwang Li
Summary: A multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated using HA-CS-NP and PVA, showing potential in inhibiting fruit decay and increasing fruit hardness.
Article
Biochemistry & Molecular Biology
Zonghua Tian, Xia Wu, Li Peng, Na Yu, Guojing Gou, Wenbao Zuo, Jianhong Yang
Summary: In this study, pH-responsive bufadienolides nanocrystals decorated by chitosan quaternary ammonium salt (HE BU NCs) were successfully constructed to improve the bioavailability, release characteristics, and intestinal transport ability of bufadienolides. In vitro studies showed that HE BU NCs could improve the internalization of bufadienolides, induce apoptosis, decrease mitochondrial membrane potential, and increase ROS levels in tumor cells. In vivo experiments demonstrated that HE BU NCs effectively targeted intestinal sites, increased retention time, and exerted antitumor activity through Caspase-3 and Bax/Bcl-2 ratio pathways.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Yuhong Zhu, Pengfei Li, Caikun Liu, Mengqi Jia, Yadong Luo, Dengfeng He, Chunyan Liao, Shiyong Zhang
Summary: The abuse of antibiotics leads to bacterial resistance, and the shortage of antibiotics has created a public health crisis. In this study, a series of photosensitive azobenzene-quaternary ammonium salt smart antibacterial agents were developed to improve antibacterial selectivity and prevent the accumulation of active agents. The compound demonstrated enhanced antibacterial activity after light irradiation and showed intelligent antibacterial properties. It has the potential to be a candidate for disinfectants in public facilities and medical architecture.
CHINESE CHEMICAL LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Hongcai Zhang, Tingting Qiu, Yifei Bai, Bin Chen, Juan Yan, Jianxiong Xu
Summary: In this study, cellulose nanocrystals were used to stabilize Lysozyme encapsulated in quaternary ammonium chitosan nanoparticles. The CNC stabilized Lys loaded QC NPs showed potential implications in the food industry for food preservation and packaging, as well as demonstrated good antibacterial activity against Staphylococcus aureus and Vibrio parahaemolyticus.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Materials Science, Multidisciplinary
Fuying Dong, Tiansong Jia, Qin Wang, Yang Liu, Lixia Ma, Shuaijie Li, Xinde Tang, Shengyu Feng
Summary: This paper presents a strategy to prevent leaching of antibacterial agents by tethering quaternary ammonium salt (QAS) groups in the matrix. The hydroxyl-terminated polysiloxanes with QAS groups were successfully synthesized and used to prepare an intrinsic antibacterial silicone rubber with excellent compatibility and durability. The hydrophilicity of the silicone rubber can be adjusted by the content of QAS groups.
MATERIALS TODAY COMMUNICATIONS
(2021)
