Chromatin accessibility and guide sequence secondary structure affect CRISPR-Cas9 gene editing efficiency
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Title
Chromatin accessibility and guide sequence secondary structure affect CRISPR-Cas9 gene editing efficiency
Authors
Keywords
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Journal
FEBS LETTERS
Volume 591, Issue 13, Pages 1892-1901
Publisher
Wiley
Online
2017-06-05
DOI
10.1002/1873-3468.12707
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Related references
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- The Impact of Chromatin Dynamics on Cas9-Mediated Genome Editing in Human Cells
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- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
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- (2014) John G Doench et al. NATURE BIOTECHNOLOGY
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems
- (2013) Wei Li et al. NATURE BIOTECHNOLOGY
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- Genome engineering using the CRISPR-Cas9 system
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- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
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- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
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- Surrogate reporters for enrichment of cells with nuclease-induced mutations
- (2011) Hyojin Kim et al. NATURE METHODS
- Minimum-free-energy distribution of RNA secondary structures: Entropic and thermodynamic properties of rare events
- (2010) S. Wolfsheimer et al. PHYSICAL REVIEW E
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