Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system

Relating conformation to function in integrin α5β1

(2016) Yang Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex

(2016) Arwen E. Frick-Cheng et al.   mBio

The CagA toxin of Helicobacter pylori: abundant production but relatively low amount translocated

(2016) Luisa F. Jiménez-Soto et al.   Scientific Reports

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion

(2016) Hong Liu et al.   Nature Microbiology

Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains

(2016) Tobias Bönig et al.   Scientific Reports

Beyond RGD: virus interactions with integrins

(2015) Hosni A. M. Hussein et al.   ARCHIVES OF VIROLOGY

Composition, structure and function of theHelicobacter pylori cagpathogenicity island encoded type IV secretion system

(2015) Steffen Backert et al.   Future Microbiology

Helicobacter pylori interferes with leukocyte migration via the outer membrane protein HopQ and via CagA translocation

(2015) Benjamin Busch et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Integrin Engagement by the Helical RGD Motif of theHelicobacter pyloriCagL Protein Is Regulated by pH-induced Displacement of a Neighboring Helix

(2015) Daniel A. Bonsor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adhesion of Several Cell Lines to Helicobacter pylori CagL Is Mediated by Integrin αVβ6 via an RGDLXXL Motif

(2015) Stephan Barden et al.   JOURNAL OF MOLECULAR BIOLOGY

Helicobacter pylori CagA and Gastric Cancer: A Paradigm for Hit-and-Run Carcinogenesis

(2014) Masanori Hatakeyama   Cell Host & Microbe

Recent advances in the structural and molecular biology of type IV secretion systems

(2014) Martina Trokter et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of a bacterial type IV secretion core complex at subnanometre resolution

(2013) Angel Rivera-Calzada et al.   EMBO JOURNAL

Characterization of the Translocation-competent Complex between theHelicobacter pyloriOncogenic Protein CagA and the Accessory Protein CagF

(2013) Daniel A. Bonsor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cag Type IV Secretion System: CagI Independent Bacterial Surface Localization of CagA

(2013) Navin Kumar et al.   PLoS One

A Helical RGD Motif Promoting Cell Adhesion: Crystal Structures of the Helicobacter pylori Type IV Secretion System Pilus Protein CagL

(2013) Stephan Barden et al.   STRUCTURE

Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA

(2012) Takeru Hayashi et al.   Cell Host & Microbe

Exploitation of integrin function by pathogenic microbes

(2012) Christof R Hauck et al.   CURRENT OPINION IN CELL BIOLOGY

Helicobacter pyloriCagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex

(2012) Tobias Wiedemann et al.   GUT

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

(2012) Masamichi Nagae et al.   JOURNAL OF CELL BIOLOGY

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

(2012) Doreen Mueller et al.   JOURNAL OF CLINICAL INVESTIGATION

CagI Is an Essential Component of the Helicobacter pylori Cag Type IV Secretion System and Forms a Complex with CagL

(2012) Kieu Thuy Pham et al.   PLoS One

Structural insights into Helicobacter pylori oncoprotein CagA interaction with  1 integrin

(2012) B. Kaplan-Turkoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An RGD Helper Sequence in CagL of Helicobacter pylori Assists in Interactions with Integrins and Injection of CagA

(2012) Jens Conradi et al.   Frontiers in Cellular and Infection Microbiology

Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins αVβ3 and α5β1

(2011) Jens Conradi et al.   AMINO ACIDS

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

Architecture of the Helicobacter pylori Cag-type IV secretion system

(2011) Laurent Terradot et al.   FEBS Journal

Integrin-mediated type IV secretion by Helicobacter: what makes it tick?

(2011) Ralf Schuelein et al.   TRENDS IN MICROBIOLOGY

Helicobacter pylori Exploits a Unique Repertoire of Type IV Secretion System Components for Pilus Assembly at the Bacteria-Host Cell Interface

(2011) Carrie L. Shaffer et al.   PLoS Pathogens

Helicobacter pylori CagL Activates ADAM17 to Induce Repression of the Gastric H, K-ATPase α Subunit

(2010) Arindam Saha et al.   GASTROENTEROLOGY

A Small Fibronectin-mimicking Protein from Bacteria Induces Cell Spreading and Focal Adhesion Formation

(2010) Nicole Tegtmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimation of the number of α-helical and β-strand segments in proteins using circular dichroism spectroscopy

(2010) Narasimha Sreerama et al.   PROTEIN SCIENCE

Expression of Helicobacter pylori CagA domains by library-based construct screening

(2009) Alessandro Angelini et al.   FEBS Journal

Structure of the outer membrane complex of a type IV secretion system

(2009) Vidya Chandran et al.   NATURE

Structure of a Type IV Secretion System Core Complex

(2009) R. Fronzes et al.   SCIENCE

Helicobacter pylori Type IV Secretion Apparatus Exploits β1 Integrin in a Novel RGD-Independent Manner

(2009) Luisa F. Jiménez-Soto et al.   PLoS Pathogens

The Highly Repetitive Region of the Helicobacter pylori CagY Protein Comprises Tandem Arrays of an α-Helical Repeat Module

(2008) Robin M. Delahay et al.   JOURNAL OF MOLECULAR BIOLOGY