Interplay between environmentally modulated feedback loops - hypoxia and circadian rhythms - two sides of the same coin?

A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes

(2017) Minoru Kobayashi et al.   FEBS Journal

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Synchronization of the mammalian circadian timing system: Light can control peripheral clocks independently of the SCN clock

(2015) Jana Husse et al.   BIOESSAYS

Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing

(2015) Reinhard Depping et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Multiplicity of Hypoxia-Inducible Transcription Factors and Their Connection to the Circadian Clock in the Zebrafish

(2015) Bernd Pelster et al.   PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY

The Impact of HIF1α on the Per2 Circadian Rhythm in Renal Cancer Cell Lines

(2014) Takashi Okabe et al.   PLoS One

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling

(2012) F. K. Pientka et al.   JOURNAL OF CELL SCIENCE

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

(2012) Tobias Eckle et al.   NATURE MEDICINE

Stabilisation and Knockdown of HIF - Two Distinct Ways Comparably Important in Radiotherapy

(2011) Mareike Ströfer et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Circadian Control of Global Gene Expression Patterns

(2010) Colleen J. Doherty et al.   Annual Review of Genetics