The dock-and-coalesce mechanism for the association of a WASP disordered region with the Cdc42 GTPase

Efficient Atomistic Simulation of Pathways and Calculation of Rate Constants for a Protein–Peptide Binding Process: Application to the MDM2 Protein and an Intrinsically Disordered p53 Peptide

(2016) Matthew C. Zwier et al.   Journal of Physical Chemistry Letters

Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors

(2016) Xiaodong Pang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Intrinsic disorder accelerates dissociation rather than association

(2016) Koji Umezawa et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Binding Rate Constants Reveal Distinct Features of Disordered Protein Domains

(2015) Jakob Dogan et al.   BIOCHEMISTRY

Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding

(2015) Munehito Arai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Electrostatic Interactions in Binding of Peptides and Intrinsically Disordered Proteins to Their Folded Targets. 1. NMR and MD Characterization of the Complex between the c-Crk N-SH3 Domain and the Peptide Sos

(2014) Yi Xue et al.   BIOCHEMISTRY

Mechanism of Folding and Binding of an Intrinsically Disordered Protein As Revealed by ab Initio Simulations

(2014) Mateusz Kurcinski et al.   Journal of Chemical Theory and Computation

Distinct mechanisms of a phosphotyrosyl peptide binding to two SH2 domains

(2014) Xiaodong Pang et al.   JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY

Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein

(2014) J. M. Rogers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling protein association mechanisms and kinetics

(2013) Huan-Xiang Zhou et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’

(2013) Joseph M. Rogers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

(2013) R. Giri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrostatically Accelerated Encounter and Folding for Facile Recognition of Intrinsically Disordered Proteins

(2013) Debabani Ganguly et al.   PLoS Computational Biology

Rate constants and mechanisms of intrinsically disordered proteins binding to structured targets

(2012) Huan-Xiang Zhou et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Prediction and Dissection of Widely-Varying Association Rate Constants of Actin-Binding Proteins

(2012) Xiaodong Pang et al.   PLoS Computational Biology

Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction

(2011) A. Bachmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated Prediction of Protein Association Rate Constants

(2011) Sanbo Qin et al.   STRUCTURE

Intrinsic disorder: signaling via highly specific but short-lived association

(2011) Huan-Xiang Zhou   TRENDS IN BIOCHEMICAL SCIENCES

Rate theories for biologists

(2010) Huan-Xiang Zhou   QUARTERLY REVIEWS OF BIOPHYSICS

Fundamental Aspects of Protein−Protein Association Kinetics

(2009) G. Schreiber et al.   CHEMICAL REVIEWS

Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding–Binding Process: A Critical Assessment of the “Fly-Casting” Mechanism

(2009) Yongqi Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility

(2009) Ina Weisswange et al.   NATURE

Mechanism of Fast Peptide Recognition by SH3 Domains

(2008) Mazen Ahmad et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding-Induced Folding of a Natively Unstructured Transcription Factor

(2008) Adrian Gustavo Turjanski et al.   PLoS Computational Biology