Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin

ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway

(2015) Lena Ho et al.   Cell Stem Cell

Apelin receptors: From signaling to antidiabetic strategy

(2015) C. Chaves-Almagro et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effects of apelin-13 on experimental ischemic stroke through suppression of inflammation

(2015) Qing Xin et al.   PEPTIDES

Apelin and energy metabolism

(2015) Chantal Bertrand et al.   Frontiers in Physiology

Apelin promotes lymphangiogenesis and lymph node metastasis

(2015) Judit Berta et al.   Oncotarget

Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems

(2015) Zhi Wang et al.   Scientific Reports

Biased Signaling Favoring Giover β-Arrestin Promoted by an Apelin Fragment Lacking the C-terminal Phenylalanine

(2014) Emilie Ceraudo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G Protein and β-Arrestin Signaling Bias at the Ghrelin Receptor

(2014) Tama Evron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

(2014) A. Pauli et al.   SCIENCE

ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor

(2013) Serene C. Chng et al.   DEVELOPMENTAL CELL

Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas

(2013) François-Xavier Picault et al.   EUROPEAN JOURNAL OF CANCER

The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis

(2013) Anne-Marie O'Carroll et al.   JOURNAL OF ENDOCRINOLOGY

The Role of Apelin in the Retina of Diabetic Rats

(2013) Qiang Lu et al.   PLoS One

Hypoxia-induced up-regulation of apelin is associated with a poor prognosis in oral squamous cell carcinoma patients

(2012) Kyun Heo et al.   ORAL ONCOLOGY

Apelin, a promising target for type 2 diabetes treatment?

(2012) Isabelle Castan-laurell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

(2011) Thibaut Duparc et al.   ANTIOXIDANTS & REDOX SIGNALING

Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension

(2011) Suparna M. Chandra et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Discovery of a Competitive Apelin Receptor (APJ) Antagonist

(2011) N. J. Maximilian Macaluso et al.   ChemMedChem

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of Human Ether-à-go-go Related Gene Modulators by Three Screening Platforms in an Academic Drug-Discovery Setting

(2010) Xi-Ping Huang et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons

(2010) Xiang Jun Zeng et al.   EXPERIMENTAL CELL RESEARCH

Apelin Expression in Human Non-small Cell Lung Cancer: Role in Angiogenesis and Prognosis

(2010) Judit Berta et al.   Journal of Thoracic Oncology

Apelin is necessary for the maintenance of insulin sensitivity

(2009) Patrick Yue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice

(2008) Cédric Dray et al.   Cell Metabolism

Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension

(2008) Carolina Tiani et al.   JOURNAL OF HEPATOLOGY

Vascular Effects of Apelin In Vivo in Man

(2008) Alan G. Japp et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Antagonism of dopamine D2 receptor/ -arrestin 2 interaction is a common property of clinically effective antipsychotics

(2008) B. Masri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA