Unacylated ghrelin normalizes skeletal muscle oxidative stress and prevents muscle catabolism by enhancing tissue mitophagy in experimental chronic kidney disease

Inflammation and Oxidative Stress in End-Stage Renal Disease Patients Treated with Hemodialysis or Peritoneal Dialysis

(2018) Vassilis Filiopoulos et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

An unconventional pathway for mitochondrial protein degradation

(2016) Zhiyuan Yao et al.   Autophagy

Unacylated Ghrelin Reduces Skeletal Muscle Reactive Oxygen Species Generation and Inflammation and Prevents High-Fat Diet–Induced Hyperglycemia and Whole-Body Insulin Resistance in Rodents

(2016) Gianluca Gortan Cappellari et al.   DIABETES

Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease

(2016) Emiko Sato et al.   Scientific Reports

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

(2016) Yuki Enoki et al.   Scientific Reports

Toll-like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease

(2016) Daniela Verzola et al.   Journal of Cachexia Sarcopenia and Muscle

The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation

(2015) Qiao Zhang et al.   NATURE IMMUNOLOGY

AST-120 ameliorates lowered exercise capacity and mitochondrial biogenesis in the skeletal muscle from mice with chronic kidney disease via reducing oxidative stress

(2015) Mikito Nishikawa et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Myostatin Activates the Ubiquitin-Proteasome and Autophagy-Lysosome Systems Contributing to Muscle Wasting in Chronic Kidney Disease

(2015) Dong-Tao Wang et al.   Oxidative Medicine and Cellular Longevity

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

(2015) Giulia Ruozi et al.   Nature Communications

Ghrelin

(2015) T.D. Müller et al.   Molecular Metabolism

Molecular regulation of autophagy and its implications for metabolic diseases

(2014) Stefan W. Ryter et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Mechanisms of muscle wasting in chronic kidney disease

(2014) Xiaonan H. Wang et al.   Nature Reviews Nephrology

Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease

(2014) Maria P. Martinez Cantarin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Insulin resistance in chronic kidney disease: new lessons from experimental models

(2013) L. Koppe et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Muscle wasting in animal models of severe illness

(2012) Milan Holecek   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Ghrelin protects against cobalt chloride-induced hypoxic injury in cardiac H9c2 cells by inhibiting oxidative stress and inducing autophagy

(2012) Xin-Xin Tong et al.   PEPTIDES

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)–nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction

(2011) R. Barazzoni et al.   DIABETOLOGIA

Review of muscle wasting associated with chronic kidney disease

(2010) Biruh T Workeneh et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

An enzymatic fluorimetric assay to quantitate 2-deoxyglucose and 2-deoxyglucose-6-phosphate for in vitro and in vivo use

(2010) Norio Yamamoto et al.   ANALYTICAL BIOCHEMISTRY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A low-protein diet supplemented with ketoacids plays a more protective role against oxidative stress of rat kidney tissue with 5/6 nephrectomy than a low-protein diet alone

(2009) Xiang Gao et al.   BRITISH JOURNAL OF NUTRITION

The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras

(2009) Joo-Yun Byun et al.   CARCINOGENESIS

Insulin Resistance in Chronic Uremia

(2009) Gianfranco Guarnieri et al.   JOURNAL OF RENAL NUTRITION

Combined effects of ghrelin and higher food intake enhance skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rats with chronic kidney disease

(2009) Rocco Barazzoni et al.   KIDNEY INTERNATIONAL

Ghrelin Gene Products and the Regulation of Food Intake and Gut Motility

(2009) C.-Y. Chen et al.   PHARMACOLOGICAL REVIEWS

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Higher total ghrelin levels are associated with higher insulin-mediated glucose disposal in non-diabetic maintenance hemodialysis patients

(2007) Rocco Barazzoni et al.   CLINICAL NUTRITION

Inflammation and Insulin Resistance in Uremia

(2007) Michela Zanetti et al.   JOURNAL OF RENAL NUTRITION