The role of secreted heat shock protein-90 (Hsp90) in wound healing - how could it shape future therapeutics?

PRAS40 Connects Microenvironmental Stress Signaling to Exosome-Mediated Secretion

(2017) Jiacong Guo et al.   MOLECULAR AND CELLULAR BIOLOGY

Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression

(2016) M Zou et al.   ONCOGENE

Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment

(2016) Hangming Dong et al.   Scientific Reports

Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigs

(2016) Ayesha Bhatia et al.   Molecular Therapy-Methods & Clinical Development

Hsp90  and Hsp90  together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing

(2015) P. Jayaprakash et al.   JOURNAL OF CELL SCIENCE

Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes

(2014) C.E. Aubert et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Heat shock proteins in fibrosis and wound healing: Good or evil?

(2014) Pierre-Simon Bellaye et al.   PHARMACOLOGY & THERAPEUTICS

Identification of the Critical Therapeutic Entity in Secreted Hsp90α That Promotes Wound Healing in Newly Re-Standardized Healthy and Diabetic Pig Models

(2014) Kathryn O'Brien et al.   PLoS One

Enhancement of FGF-1 release along with cytosolic proteins from rat astrocytes by hydrogen peroxide

(2013) Jin-ichi Ito et al.   BRAIN RESEARCH

Extracellular Heat Shock Protein 90 Signals through Subdomain II and the NPVY Motif of LRP-1 Receptor to Akt1 and Akt2: a Circuit Essential for Promoting Skin Cell Migration In Vitro and Wound Healing In Vivo

(2013) F. Tsen et al.   MOLECULAR AND CELLULAR BIOLOGY

Secreted heat shock protein-90 (Hsp90) in wound healing and cancer

(2011) Wei Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Advanced Glycation End Products, Measured as Skin Autofluorescence and Diabetes Complications: A Systematic Review

(2011) Dieuwke C. Bos et al.   Diabetes Technology & Therapeutics

A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice

(2011) Chieh-Fang Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α–positive tumors

(2011) Divya Sahu et al.   MOLECULAR BIOLOGY OF THE CELL

Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells

(2011) T. Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular heat shock protein HSP90β secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-β1

(2010) Shigeki Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Secreted Heat Shock Protein 90α Induces Colorectal Cancer Cell Invasion through CD91/LRP-1 and NF-κB-mediated Integrin αVExpression

(2010) Jinn-Shiun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat Shock Proteins in Diabetes and Wound Healing

(2009) Mustafa Atalay et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90  autocrine signaling to promote keratinocyte migration

(2009) D. T. Woodley et al.   JOURNAL OF CELL SCIENCE

The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy

(2009) Xiaofeng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Considerations for selecting the correct animal model for dermal wound-healing studies

(2008) William J. Lindblad   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS