Brain circuits and neurochemical systems in essential tremor: insights into current and future pharmacotherapeutic approaches

GABA A receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [ 18 F]flumazenil PET

(2017) Adrienne Müller Herde et al.   NEUROIMAGE

Sub-synaptic localization of Cav3.1 T-type calcium channels in the thalamus of normal and parkinsonian monkeys

(2016) Erdong Chen et al.   Brain Structure & Function

Effect of Primidone on Dentate Nucleus γ-Aminobutyric Acid Concentration in Patients With Essential Tremor

(2016) Elan D. Louis et al.   CLINICAL NEUROPHARMACOLOGY

Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis

(2016) Matthew Choe et al.   MOVEMENT DISORDERS

Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies

(2016) Huo Lu et al.   Frontiers in Neural Circuits

Ontogenic Changes and Differential Localization of T-type Ca2+ Channel Subunits Cav3.1 and Cav3.2 in Mouse Hippocampus and Cerebellum

(2016) Carolina Aguado et al.   Frontiers in Neuroanatomy

Linking Essential Tremor to the Cerebellum: Neurochemical Evidence

(2015) Juan Marin-Lahoz et al.   CEREBELLUM

Linking Essential Tremor to the Cerebellum—Animal Model Evidence

(2015) Adrian Handforth   CEREBELLUM

The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development

(2015) Tamara Stojanovic et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Climbing fiber synaptic changes correlate with clinical features in essential tremor

(2015) R. J. Louis et al.   NEUROLOGY

Testing for alcohol sensitivity of tremor amplitude in a large cohort with essential tremor

(2015) Franziska Hopfner et al.   PARKINSONISM & RELATED DISORDERS

Reduced Purkinje cell dendritic arborization and loss of dendritic spines in essential tremor

(2014) Elan D. Louis et al.   BRAIN

Understanding Essential Tremor: Progress on the Biological Front

(2014) Elan D. Louis   Current Neurology and Neuroscience Reports

Essential tremor is not associated with cerebellar Purkinje cell loss

(2014) Claire Symanski et al.   MOVEMENT DISORDERS

Cerebellar Inhibitory Input to the Inferior Olive Decreases Electrical Coupling and Blocks Subthreshold Oscillations

(2014) Yaara Lefler et al.   NEURON

Purkinje cell axonal anatomy: quantifying morphometric changes in essential tremor versus control brains

(2013) Rachel Babij et al.   BRAIN

Quantification of cerebellar hemispheric purkinje cell linear density: 32 ET cases versus 16 controls

(2013) Elan D. Louis et al.   MOVEMENT DISORDERS

Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain

(2013) H. Hörtnagl et al.   NEUROSCIENCE

Re-thinking the biology of essential tremor: From models to morphology

(2013) Elan D. Louis   PARKINSONISM & RELATED DISORDERS

Molecular mechanisms of antiseizure drug activity at GABAA receptors

(2013) L. John Greenfield   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Gaba and serotonin molecular neuroimaging in essential tremor: A clinical correlation study

(2012) A. Gironell et al.   PARKINSONISM & RELATED DISORDERS

Lack of CaV3.1 channels causes severe motor coordination defects and an age-dependent cerebellar atrophy in a genetic model of essential tremor

(2011) Ki-Young Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Defective dentate nucleus GABA receptors in essential tremor

(2011) Sarah Paris-Robidas et al.   BRAIN

Evidence-based guideline update: Treatment of essential tremor: Report of the Quality Standards Subcommittee of the American Academy of Neurology

(2011) T. A. Zesiewicz et al.   NEUROLOGY

GABAA receptor- and GABA transporter polymorphisms and risk for essential tremor

(2010) S. Thier et al.   EUROPEAN JOURNAL OF NEUROLOGY

"Hairy Baskets” Associated With Degenerative Purkinje Cell Changes in Essential Tremor

(2010) Cordelia R. Erickson-Davis et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

GABAergic Dysfunction in Essential Tremor: An 11C-Flumazenil PET Study

(2010) H. Boecker et al.   JOURNAL OF NUCLEAR MEDICINE

T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor

(2010) Adrian Handforth et al.   NEUROPHARMACOLOGY

Cerebellar Purkinje cell loss is not pathognomonic of essential tremor

(2010) A.H. Rajput et al.   PARKINSONISM & RELATED DISORDERS

CaV3.1 is a tremor rhythm pacemaker in the inferior olive

(2010) Y.-G. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Tremors

(2009) Elan D. Louis   ARCHIVES OF NEUROLOGY

Synchronized brain network associated with essential tremor as revealed by magnetoencephalography

(2009) Alfons Schnitzler et al.   MOVEMENT DISORDERS

Ethanol Decreases Purkinje Neuron Excitability by Increasing GABA Release in Rat Cerebellar Slices

(2008) M. Mameli et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Tiagabine for essential tremor: An open-label trial

(2008) Alexandre Gironell et al.   MOVEMENT DISORDERS