Recent advances in the development and use of molecular tests to predict antimicrobial resistance in Neisseria gonorrhoeae

WGS to predict antibiotic MICs for Neisseria gonorrhoeae

(2017) David W. Eyre et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Molecular Epidemiology and Antimicrobial Resistance of Neisseria gonorrhoeae in Australia: A Nationwide Cross-Sectional Study, 2012

(2016) Ella Trembizki et al.   CLINICAL INFECTIOUS DISEASES

Molecular tests for the detection of antimicrobial resistant Neisseria gonorrhoeae

(2016) Nicola Low et al.   CURRENT OPINION IN INFECTIOUS DISEASES

WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L)Neisseria gonorrhoeaeisolates in Europe from 2009 to 2014

(2016) Susanne Jacobsson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mixed gonococcal infections in a high-risk population, Sydney, Australia 2015: implications for antimicrobial resistance surveillance?

(2016) Namraj Goire et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The novel 2016 WHONeisseria gonorrhoeaereference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization

(2016) Magnus Unemo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Accurate detection ofNeisseria gonorrhoeaeciprofloxacin susceptibility directly from genital and extragenital clinical samples: towards genotype-guided antimicrobial therapy

(2016) Marcus J. Pond et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014

(2016) Walter Demczuk et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Performance and Verification of a Real-Time PCR Assay Targeting thegyrAGene for Prediction of Ciprofloxacin Resistance in Neisseria gonorrhoeae: TABLE 1

(2016) P. Hemarajata et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multiplex Real-Time PCR Assay with High-Resolution Melting Analysis for Characterization of Antimicrobial Resistance in Neisseria gonorrhoeae

(2016) Valentina Donà et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Further evidence to support the individualised treatment of gonorrhoea with ciprofloxacin

(2016) Ella Trembizki et al.   LANCET INFECTIOUS DISEASES

Epidemiological typing ofNeisseria gonorrhoeaeand detection of markers associated with antimicrobial resistance directly from urine samples using next generation sequencing

(2016) R M A Graham et al.   SEXUALLY TRANSMITTED INFECTIONS

Antibiotic-Resistant Neisseria gonorrhoeae Spread Faster with More Treatment, Not More Sexual Partners

(2016) Stephanie M. Fingerhuth et al.   PLoS Pathogens

Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan

(2015) Ken Shimuta et al.   BMC INFECTIOUS DISEASES

Emergence of decreased susceptibility and resistance to extended-spectrum cephalosporins inNeisseria gonorrhoeaein Korea

(2015) Hyukmin Lee et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A real-time PCR assay for direct characterization of theNeisseria gonorrhoeaeGyrA 91 locus associated with ciprofloxacin susceptibility

(2015) Cameron Buckley et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Molecular Assay for Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae Isolates from Cultures and Clinical Nucleic Acid Amplification Test Specimens

(2015) S. W. Peterson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Molecular Assay for Detection of Genetic Markers Associated with Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae

(2015) S. W. Peterson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting

(2015) Lori Newman et al.   PLoS One

Characterization of Neisseria gonorrhoeaeisolates detected in Switzerland (1998–2012): emergence of multidrug-resistant clones less susceptible to cephalosporins

(2014) Andrea Endimiani et al.   BMC INFECTIOUS DISEASES

Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future

(2014) M. Unemo et al.   CLINICAL MICROBIOLOGY REVIEWS

Antimicrobial resistance, genetic resistance determinants for ceftriaxone and molecular epidemiology of Neisseria gonorrhoeae isolates in Nanjing, China

(2014) Shao-Chun Chen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High-throughput informative single nucleotide polymorphism-based typing of Neisseria gonorrhoeae using the Sequenom MassARRAY iPLEX platform

(2014) E. Trembizki et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study

(2014) Yonatan H Grad et al.   LANCET INFECTIOUS DISEASES

A New Multidrug-Resistant Strain of Neisseria gonorrhoeae in Australia

(2014) Monica M. Lahra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Verified clinical failure with cefotaxime 1g for treatment of gonorrhoea in the Netherlands: a case report

(2014) Alje P van Dam et al.   SEXUALLY TRANSMITTED INFECTIONS

First Three Neisseria gonorrhoeae Isolates with High-Level Resistance to Azithromycin in Sweden: a Threat to Currently Available Dual-Antimicrobial Regimens for Treatment of Gonorrhea?

(2013) Magnus Unemo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011

(2013) Birgitta Olsen et al.   BMC INFECTIOUS DISEASES

Neisseria gonorrhoeae and extended-spectrum cephalosporins in California: surveillance and molecular detection of mosaic penA

(2013) Severin Gose et al.   BMC INFECTIOUS DISEASES

Polymerase chain reaction-based screening for the ceftriaxone-resistant Neisseria gonorrhoeae F89 strain

(2013) N Goire et al.   Eurosurveillance

Determination of Neisseria gonorrhoeae susceptibility to ciprofloxacin in clinical specimens from men using a real-time PCR assay

(2013) M.P. Magooa et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae

(2013) Elena N. Ilina et al.   Frontiers in Microbiology

Neisseria gonorrhoeae Strain with High-Level Resistance to Spectinomycin Due to a Novel Resistance Mechanism (Mutated Ribosomal Protein S5) Verified in Norway

(2012) M. Unemo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

TaqMan Real-Time Quantitative PCR Assay for Detection of Fluoroquinolone-Resistant Neisseria gonorrhoeae

(2012) LiHong Zhao et al.   CURRENT MICROBIOLOGY

Multiplex Bead Suspension Array for Screening Neisseria gonorrhoeae Antibiotic Resistance Genetic Determinants in Noncultured Clinical Samples

(2012) Sergey Balashov et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The influence of target population on nonculture-based detection of markers of Neisseria gonorrhoeae antimicrobial resistance

(2012) Namraj Goire et al.   Sexual Health

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

(2011) Makoto Ohnishi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: NovelpenAMosaic Allele in a Successful International Clone Causes Treatment Failure

(2011) Magnus Unemo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enhanced gonococcal antimicrobial surveillance in the era of ceftriaxone resistance: a real-time PCR assay for direct detection of the Neisseria gonorrhoeae H041 strain

(2011) N. Goire et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Molecular Characterization of Quinolone-Resistant Neisseria gonorrhoeae Isolates from Brazil

(2011) A. A. Uehara et al.   JOURNAL OF CLINICAL MICROBIOLOGY

High-Level Azithromycin Resistance Occurs in Neisseria gonorrhoeae as a Result of a Single Point Mutation in the 23S rRNA Genes

(2010) S. A. Chisholm et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Analysis of Antimicrobial Resistance Mechanisms inNeisseria gonorrhoeaeIsolates from Ontario, Canada

(2010) Vanessa G. Allen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins inNeisseria gonorrhoeae: Role of Epistatic Mutations

(2010) Joshua Tomberg et al.   BIOCHEMISTRY

Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone

(2010) S.-G. Lee et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Cefixime in Neisseria gonorrhoeae

(2009) S. Zhao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Detection of quinolone-resistant Neisseria gonorrhoeae in urogenital specimens with the use of real-time polymerase chain reaction

(2008) et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Rapid Detection of the Mosaic Structure of the Neisseria gonorrhoeae penA Gene, Which Is Associated with Decreased Susceptibilities to Oral Cephalosporins

(2008) S. Ochiai et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone

(2008) Kazuyoshi Osaka et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY