A novel JAK inhibitor JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

(2016) Diamant Thaçi et al.   LANCET

The translational revolution and use of biologics in patients with inflammatory skin diseases

(2015) Shinji Noda et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling

(2015) Wataru Amano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial

(2015) Diamant Thaçi et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Treatment of recalcitrant atopic dermatitis with the oral Janus kinase inhibitor tofacitinib citrate

(2015) Lauren L. Levy et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial

(2015) Hervé Bachelez et al.   LANCET

Type I/II cytokines, JAKs and new strategies for treating autoimmune diseases

(2015) Daniella M. Schwartz et al.   Nature Reviews Rheumatology

Mast cells and basophils in cutaneous immune responses

(2014) A. Otsuka et al.   ALLERGY

The importance of TSLP in allergic disease and its role as a potential therapeutic target

(2014) Antonella Cianferoni et al.   Expert Review of Clinical Immunology

Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo

(2014) Atsuo Tanimoto et al.   INFLAMMATION RESEARCH

Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 Axis

(2014) Melissa G. Works et al.   JOURNAL OF IMMUNOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Robert Sidbury et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Lawrence F. Eichenfield et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

New concept of the pathogenesis of atopic dermatitis: Interplay among the barrier, allergy, and pruritus as a trinity

(2013) Kenji Kabashima   JOURNAL OF DERMATOLOGICAL SCIENCE

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

Guidelines for treatment of atopic eczema (atopic dermatitis) Part II

(2012) J. Ring et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Guidelines for treatment of atopic eczema (atopic dermatitis) Part I

(2012) J. Ring et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Contrasting pathogenesis of atopic dermatitis and psoriasis—Part II: Immune cell subsets and therapeutic concepts

(2011) Emma Guttman-Yassky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Contrasting pathogenesis of atopic dermatitis and psoriasis—Part I: Clinical and pathologic concepts

(2011) Emma Guttman-Yassky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pyridone 6, a Pan-JAK Inhibitor, Ameliorates Allergic Skin Inflammation of NC/Nga Mice via Suppression of Th2 and Enhancement of Th17

(2011) R. Nakagawa et al.   JOURNAL OF IMMUNOLOGY

Preclinical Evaluation of Local JAK1 and JAK2 Inhibition in Cutaneous Inflammation

(2011) Jordan S. Fridman et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Analysis of the Mechanism for the Development of Allergic Skin Inflammation and the Application for Its Treatment: Mouse Models for the Development of Remedies for Human Allergic Dermatitis

(2009) Naoki Inagaki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2009) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2009) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2008) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

(2008) Craig L Leonardi et al.   LANCET

Atopic Dermatitis

(2008) Thomas Bieber   NEW ENGLAND JOURNAL OF MEDICINE