Combined activity of temozolomide and the mTOR inhibitor temsirolimus in metastatic melanoma involves DKK1

Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy

(2014) Nethia Mohana-Kumaran et al.   Pigment Cell & Melanoma Research

A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

(2014) B. C. Grabiner et al.   Cancer Discovery

Phase II Study of Temozolomide (TMZ) and Everolimus (RAD001) Therapy for Metastatic Melanoma

(2013) Roxana S. Dronca et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines

(2013) Marzieh Badinloo et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Vemurafenib Potently Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in BRAFV600E Melanoma Cells

(2013) D. Beck et al.   Science Signaling

Dickkopf-1 inhibits the invasive activity of melanoma cells

(2012) J. Chen et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

(2012) M. Mao et al.   CLINICAL CANCER RESEARCH

Dickkopf-1 inhibits thyroid cancer cell survival and migration through regulation of β-catenin/E-cadherin signaling

(2012) Sun Wook Cho et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Selective Induction of Cell Death in Melanoma Cell Lines through Targeting of Mcl-1 and A1

(2012) Daniela Senft et al.   PLoS One

Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling

(2011) Nikhil Wagle et al.   JOURNAL OF CLINICAL ONCOLOGY

β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

(2011) Tobias Sinnberg et al.   PLoS One

MicroRNA miR-183 Functions as an Oncogene by Targeting the Transcription Factor EGR1 and Promoting Tumor Cell Migration

(2010) A. L. Sarver et al.   CANCER RESEARCH

Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma

(2010) Hiroshi Hirata et al.   INTERNATIONAL JOURNAL OF CANCER

Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma

(2009) Suhu Liu et al.   CLINICAL & EXPERIMENTAL METASTASIS

Combined Inhibition of MAPK and mTOR Signaling Inhibits Growth, Induces Cell Death, and Abrogates Invasive Growth of Melanoma Cells

(2008) Konstantinos G. Lasithiotakis et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

(2008) Tobias Sinnberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY