Article
Cardiac & Cardiovascular Systems
Kathy K. Griendling, Livia L. Camargo, Francisco J. Rios, Rheure Alves-Lopes, Augusto C. Montezano, Rhian M. Touyz
Summary: The link between oxidative stress and hypertension has been established in animal models, but remains elusive in humans. Research has expanded our understanding of reactive oxygen species and their impact on signaling pathways, with potential for developing novel antihypertensive therapies.
CIRCULATION RESEARCH
(2021)
Article
Cell Biology
Michiko Tashiro, Masato Konishi, Makino Watanabe, Utako Yokoyama
Summary: The intracellular concentration of free Mg2+ ([Mg2+]i) plays a crucial role in cellular functions. Reactive oxygen species (ROS) can affect [Mg2+]i homeostasis and lead to cellular damage. This study demonstrates that ROS decrease intracellular Mg2+ levels in cardiomyocytes through a Na+-independent Mg2+ efflux system, potentially contributing to ROS-induced cardiac dysfunction.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jiaqi Zhu, Peter Langer, Claas Ulrich, Juergen Eberle
Summary: This study investigated the efficacy of three indirubin derivatives in four cSCC cell lines, showing significant effects on cell proliferation, viability, and apoptosis. The mechanisms of action involved induction of reactive oxygen species and activation of various apoptotic pathways, highlighting the importance of ROS in antitumor effects of indirubins.
Article
Biophysics
Fredrick Nwude Eze, Titilope John Jayeoye, Adesola Julius Tola
Summary: In this study, biogenic silver nanoparticles (Cafi-AgNPs) were successfully synthesized using Cassia fistula-phenolic-rich extract (Cafi), demonstrating excellent antioxidant properties and cytocompatibility. Cafi-AgNPs also showed potential in H2O2 sensing applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Plant Sciences
Taras Pasternak, Klaus Palme, Jose Manuel Perez-Perez
Summary: Reactive oxygen species (ROS) play a dual role in plant biology, acting as important signal transduction molecules and as toxic byproducts of aerobic metabolism that accumulate in cells upon exposure to different stressors and lead to cell death. In this study, it was found that ROS is an important modulator of auxin distribution and response in plant roots. Genetic alterations in ROS balance led to defective auxin distribution and growth-related responses in roots.
Article
Chemistry, Physical
Sihan Jia, Sunkui Ke, Li Tu, Shengqiang Chen, Bingkun Luo, Yeqi Xiong, Yang Li, Peiyuan Wang, Shefang Ye
Summary: In this study, a tumor microenvironment (TME)-responsive Cu-based metal-mesoporous organosilica nanoplatform incorporating vitamin k3 (VK3) was developed for enhanced chemodynamic therapy (CDT) of cancer. The nanoplatform could deplete glutathione (GSH) and specifically regenerate hydrogen peroxide (H2O2), resulting in synergistic CDT against tumors. Both in vitro and in vivo studies demonstrated the excellent biosafety and highly efficient tumor therapy potential of the CuO@MON-PEG/VK3 nanoplatform with multiple oxidative stress amplification.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Medicine, Research & Experimental
Min Seok Kwun, JiEun Yun, Dong Gun Lee
Summary: The study elucidated the antibacterial mode of action induced by indole-3-carbinol in E. coli, showing that it accumulates ROS and causes DNA damage, leading to apoptosis-like death. Contribution of each ROS displayed respective manner, with OH- exerting the most potent influence whereas O-2(-) showed least impact. The findings suggest the potential of I3C as a candidate for drugs regulating E. coli and enhance the understanding of ROS and cellular processes during oxidative stress in bacteria.
Review
Chemistry, Analytical
Wanchao Yu, Lixia Zhao
Summary: ROS, as important oxidizing species in ecosystems, play various roles and monitoring their concentration is crucial for the environment. The chemiluminescence method has attracted attention for ROS detection due to its high sensitivity and simplicity, showing advances in recent years.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Chaoqun Tan, Tianyu Sheng, Qinglong Xu, Tianhui Xu, Kechun Sun, Lin Deng, Wei Xu
Summary: Cobalt doped iron oxychloride (Co-FeOCl) was synthesized and used as a catalyst in Fenton degradation of paracetamol (APAP) and phenacetin (PNCT) for the first time. The study found that the catalyst showed high removal efficiency under certain conditions, and identified the primary reactive oxygen species in the system as well as proposed a possible activation mechanism.
Review
Chemistry, Analytical
Rohini Kumari, Daphika S. Dkhar, Supratim Mahapatra, Divya, Rahul Kumar, Pranjal Chandra
Summary: Reactive oxygen species play an important role in cell signaling but excessive production is associated with various diseases. Traditional detection methods have limitations, while biosensing technology has emerged as a major approach. This review discusses recent biosensors for monitoring reactive oxygen species and highlights the progress of nanotechnology and biomimetic engineering in biosensing.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Huisi Yang, Juan Zhou, Jing Bao, Yi Ma, Jun Zhou, Caihong Shen, Huibo Luo, Mei Yang, Changjun Hou, Danqun Huo
Summary: The addition of graphene increases the specific surface area of the MoS2/rGO composite, leading to improved detection sensitivity towards H2O2. This composite material, prepared using a simple method, is expected to play a significant role in clinical applications.
MICROCHEMICAL JOURNAL
(2021)
Article
Multidisciplinary Sciences
Yu Xia, Juan Li, Yuanzheng Zhang, Yongguang Yin, Bolei Chen, Yong Liang, Guibin Jiang, Richard N. Zare
Summary: Spontaneous generation of reactive oxygen species (ROS) occurs when water vapor contacts hydrogen-bonded hydroxyl groups on a silicate surface, which is confirmed by time-resolved FT-IR spectroscopy. The involvement of water vapor in ROS generation is further supported by studying the reaction of D2O vapor and hydroxyl groups on a silicate surface. It is proposed that the change of the hydrogen-bonding network and electron transfer onto the silicate surface during water vapor-solid contact process contribute to ROS production.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Engineering, Chemical
Yaru Wang, Yeqing Lyu, Shaona Wang, Hao Du
Summary: The main ROS generated in phosphoric acid solution from oxygen microbubbles was identified as H2O2, with its production dependent on temperature and phosphoric acid concentration. Under optimal conditions, the production of H2O2 from microbubbles facilitated the oxidation of ferrous ions and significantly reduced the reaction activation energy.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Biochemistry & Molecular Biology
J. Jeffrey Morris, Andrew L. Rose, Zhiying Lu
Summary: Reactive oxygen species (ROS) are omnipresent in the ocean, originating from both biological and non-biological processes. They directly and indirectly impact marine organisms and biogeochemistry, shaping microbial communities and influencing steady-state ROS concentrations. Climate change may increase ROS levels in the ocean, affecting the ecology and chemistry of the future ocean.
Review
Plant Sciences
Ana Jimenez, Francisca Sevilla, Maria Carmen Marti
Summary: Understanding the molecular mechanisms involved in how plants perceive and respond to environmental stimuli is crucial for their adaptation to climate change. The coordination of daily cycles and stress response, as well as the crosstalk between second messengers like Ca2+, ROS, and hormones, play key roles in plant adaptation and survival under stress. The circadian clock, along with Ca2+ and hormone signaling pathways, is crucial in controlling plant adaptation to stress, highlighting the importance of studying the relationship between circadian clocks and ROS homeostasis network.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Meeting Abstract
Biochemistry & Molecular Biology
Virginia Rubio, Ana I. Garcia-Perez, Angel Herraez, Carlos Ordonez, Gema Herranz, M. Cristina Tejedor, Jose C. Diez
FREE RADICAL BIOLOGY AND MEDICINE
(2017)
Meeting Abstract
Biochemistry & Molecular Biology
Virginia Rubio, Ana I. Garcia-Perez, Angel Herraez, Carlos Ordonez, Gema Herranz, M. Cristina Tejedor, Jose C. Diez
FREE RADICAL BIOLOGY AND MEDICINE
(2017)
Article
Biotechnology & Applied Microbiology
Virginia Rubio, Ana I. Garcia-Perez, M. Cristina Tejedor, Angel Herraez, Jose C. Diez
BIOMED RESEARCH INTERNATIONAL
(2017)
Article
Biochemistry & Molecular Biology
Virginia Rubio, Ana Garcia-Perez, Angel Herraez, Jose C. Diez
CHEMICO-BIOLOGICAL INTERACTIONS
(2018)
Article
Neurosciences
Juan Ramon Perea, Esther Lopez, Jose Carlos Diez-Ballesteros, Jesus Avila, Felix Hernandez, Marta Bolos
FRONTIERS IN NEUROSCIENCE
(2019)
Article
Anthropology
Angel Herraez, Noemi Lopez-Ejeda, Maria Dolores Marrodan, Marisa Gonzalez-Montero de Espinosa
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Angel Herraez
Summary: This article provides guidance on choosing, designing, and implementing virtual laboratories and simulations of experimental environments and techniques in order to overcome difficulties in traditional laboratory training. The objectives are to enhance active learning, support practical sessions, and provide alternative exposure to laboratory work when real experiments are not feasible.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
(2022)
Article
Anthropology
Maria Dolores Marrodan Serrano, Estela Roman, Margarita Carmenate, Marisa Gonzalez-Montero de Espinosa, Angel Herraez, Enma Laura Alfaro, Delia Beatriz Lomaglio, Noemi Lopez-Ejeda, Maria Soledad Mesa, Vanessa Vazquez, Betty Mendez Perez, Juana Maria Melendez, Susana Moreno-Romero, Consuelo Prado, Jose Edgardo Dipierri
Summary: This study aimed to provide percentiles of waist circumference for Hispanic-American children and adolescents, and compare them with other international references. Results showed that boys had higher waist circumference at different percentiles, and there was high variability in waist circumference percentiles among children from diverse sociocultural and geographical contexts.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2021)
Article
Anthropology
Angel Herraez, Maria Dolores Marrodan, Marisa Gonzalez-Montero de Espinosa
Summary: The study analyzed the secular change of cormic index in Spanish schoolchildren from 1887 to 1924, showing a decrease in cormic index among Spanish male children over the decades.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Stefan Kuhn, Lianne H. E. Wieske, Paul Trevorrow, Daniel Schoeber, Nils E. Schloerer, Jean-Marc Nuzillard, Pavel Kessler, Jochen Junker, Angel Herraez, Christophe Fares, Mate Erdelyi, Damien Jeannerat
Summary: The NMReDATA format is proposed as a standardized way to store and exchange NMR data and metadata of chemical compounds. This paper discusses analytical workflows utilizing the NMReDATA format and provides a repository of sample data for validating software packages.
MAGNETIC RESONANCE IN CHEMISTRY
(2021)
Article
Anthropology
Angel Herraez, Maria Dolores Marrodan, Marisa Gonzalez-Montero de Espinosa
Summary: The study analyzed hand grip strength data of children attending summer camps organized by the Spanish National Pedagogic Museum, finding that their grip strength was significantly lower than current values. The attendees displayed low values of height and hand grip strength, both below contemporary standards, indicating a long-term historical impact.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2022)
Article
Anthropology
M. D. Marrodan, M. Gonzalez-Montero de Espinosa, A. Herraez, E. L. Alfaro, I. F. Bejarano, M. Carrnenate, D. B. Lornaglio, N. Lopez-Ejeda, A. Martinez, M. S. Mesa, B. Mendez Perez, J. M. Melendez, S. Moreno-Romero, J. L. Pacheco, V. Vazquez, J. E. Dipierri
HOMO-JOURNAL OF COMPARATIVE HUMAN BIOLOGY
(2017)