Processing thermally labile drugs by hot-melt extrusion: The lesson with gliclazide

Published 2017 View Full Article

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Title
Processing thermally labile drugs by hot-melt extrusion: The lesson with gliclazide
Authors
Keywords
Melt extrusion, Process optimization, AFFINISOL HPMC HME, Solid dispersion, Degradation, Arrhenius kinetics, Amorphous
Journal
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Volume 119, Issue -, Pages 56-67
Publisher
Elsevier BV
Online
2017-06-03
DOI
10.1016/j.ejpb.2017.05.014

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