Effects of frequently used pharmaceutical excipients on the organic cation transporters 1–3 and peptide transporters 1/2 stably expressed in MDCKII cells

Title

Effects of frequently used pharmaceutical excipients on the organic cation transporters 1–3 and peptide transporters 1/2 stably expressed in MDCKII cells

Authors

Keywords

Pharmaceutical excipients, Solubilizing agents, Drug transporter, Uptake transport, Organic cation transporter (OCT), Peptide transporter (PEPT), Polyethylene glycol (PEG), Hydroxypropyl-β-cyclodextrin, Solutol HS 15 (macrogol 15 hydroxystearate, polyoxyl 15 hydroxystearate), Cremophor, Tween (polysorbate), Kolliphor (poloxamer), MDCK cells, In vitro, Cell model, Competition assay, Inhibition assay

Journal

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Volume 112, Issue -, Pages 187-195

Publisher

Elsevier BV

Online

2016-11-27

DOI

10.1016/j.ejpb.2016.11.028