The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation

Published 2017 View Full Article

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Title
The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation
Authors
Keywords
Binding kinetics, Rebinding, Distribution, Pharmacokinetics, Rate-limiting step, Diffusion
Journal
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 109, Issue -, Pages S83-S89
Publisher
Elsevier BV
Online
2017-05-12
DOI
10.1016/j.ejps.2017.05.024

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