A structure-guided optimization of pyrido[2,3- d ]pyrimidin-7-ones as selective inhibitors of EGFR L858R/T790M mutant with improved pharmacokinetic properties
A structure-guided optimization of pyrido[2,3- d ]pyrimidin-7-ones as selective inhibitors of EGFR L858R/T790M mutant with improved pharmacokinetic properties
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