Design, synthesis and biological evaluation of new pyrazolyl-ureas and imidazopyrazolecarboxamides able to interfere with MAPK and PI3K upstream signaling involved in the angiogenesis

Title
Design, synthesis and biological evaluation of new pyrazolyl-ureas and imidazopyrazolecarboxamides able to interfere with MAPK and PI3K upstream signaling involved in the angiogenesis
Authors
Keywords
p38MAPK phosphorylation, ERK1/2 phosphorylation, Akt phosphorylation, Migration, Pyrazolylureas, Imidazopyrazole derivatives
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 133, Issue -, Pages 24-35
Publisher
Elsevier BV
Online
2017-03-28
DOI
10.1016/j.ejmech.2017.03.066

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