Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease

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Title
Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease
Authors
Keywords
β-secretase inhibitors, Alzheimer's disease, Transition state mimics, Structure-based drug design, Structure activity relationship, Isophthalic acid derivatives, Molecular modeling
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 125, Issue -, Pages 1213-1224
Publisher
Elsevier BV
Online
2016-11-12
DOI
10.1016/j.ejmech.2016.11.021

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