Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors

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Title
Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors
Authors
Keywords
Quinazolinone, Isoindolinone, Hedgehog pathway, Structure hopping, Smoothened, Gli
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 125, Issue -, Pages 1036-1050
Publisher
Elsevier BV
Online
2016-10-20
DOI
10.1016/j.ejmech.2016.10.040

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