Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis

Title
Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis
Authors
Keywords
Alzheimer's disease, β-Secretase inhibitor, Groebke–Blackburn–Bienayme reaction, Imidazopyridines, Phthalimide, Molecular docking
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 138, Issue -, Pages 729-737
Publisher
Elsevier BV
Online
2017-06-24
DOI
10.1016/j.ejmech.2017.06.040

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