Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells

Title
Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells
Authors
Keywords
Apoptosis, Cytotoxicity, PI3K/Akt/mTOR signaling pathway, Molecular modeling, Pyrazolochalcones
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 139, Issue -, Pages 305-324
Publisher
Elsevier BV
Online
2017-07-25
DOI
10.1016/j.ejmech.2017.07.056

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