Journal
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
Volume -, Issue 35, Pages 4117-4122Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejic.201700775
Keywords
Titanium; Drug delivery; Triclosan; Hydrolysis; Thermolysis behavior
Categories
Funding
- Swedish Research Council (Vetenskapsradet) [2014-3938]
Ask authors/readers for more resources
We present the structure of a new tetranuclear titanium oxo complex containing the antibacterial agent triclosan. This provides a good model for the interaction between triclosan and titania, which may be used for drug-delivery applications. The antibacterial activity of the hydrolyzed complex against Staphylococcus aureus is investigated. Thereafter, we use the obtained titanium oxo complex to demonstrate its susceptibility towards hydrolysis, contrary to the widespread belief that titanium oxo complexes are water-stable, and demonstrate that it transforms into titania (anatase) on contact with water. Both hydrolysis and thermolysis of the complex yield titania particles, of very uniform size and shape, that connect into 3D nanostructures; this is of interest for practical applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available