Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers

Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility GeneXRCC2

(2016) Florentine S. Hilbers et al.   HUMAN MUTATION

No evidence that protein truncating variants inBRIP1are associated with breast cancer risk: implications for gene panel testing

(2016) Douglas F Easton et al.   JOURNAL OF MEDICAL GENETICS

Inherited Mutations in Women With Ovarian Carcinoma

(2016) Barbara M. Norquist et al.   JAMA Oncology

The development of PARP inhibitors in ovarian cancer: from bench to bedside

(2015) Yvette Drew   BRITISH JOURNAL OF CANCER

Breast Cancer in a RAD51D Mutation Carrier: Case Report and Review of the Literature

(2015) Jennifer L. Baker et al.   Clinical Breast Cancer

Genetic testing forRAD51Cmutations: in the clinic and community

(2015) V. Sopik et al.   CLINICAL GENETICS

Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics

(2015) Massimo Bogliolo et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Arg188His polymorphism in the XRCC2 gene and the risk of ovarian cancer: a meta-analysis

(2015) M. Zhai et al.   GENETICS AND MOLECULAR RESEARCH

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

(2015) Honglin Song et al.   JOURNAL OF CLINICAL ONCOLOGY

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

(2015) Rohit Prakash et al.   Cold Spring Harbor Perspectives in Biology

RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families

(2015) Liisa M Pelttari et al.   SpringerPlus

RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families

(2014) Ana Blanco et al.   BREAST CANCER RESEARCH AND TREATMENT

Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes

(2014) Laurent Castéra et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of a breast cancer family double heterozygote for RAD51C and BRCA2 gene mutations

(2014) Lise B. Ahlborn et al.   Familial Cancer

Breast-Cancer Risk in Families with Mutations in PALB2

(2014) Antonis C. Antoniou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of XRCC2 Arg188His Polymorphism on Cancer Susceptibility: A Meta-Analysis

(2014) Yazhou He et al.   PLoS One

Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers

(2014) Heidrun Gevensleben et al.   VIRCHOWS ARCHIV

Germline mutation in the RAD51B gene confers predisposition to breast cancer

(2013) Lisa Golmard et al.   BMC CANCER

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer

(2013) Kristen S. Purrington et al.   CARCINOGENESIS

About 1% of the breast and ovarian Spanish families testing negative forBRCA1andBRCA2are carriers ofRAD51Dpathogenic variants

(2013) Sara Gutiérrez-Enríquez et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

(2013) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

(2013) A. Min et al.   MOLECULAR CANCER THERAPEUTICS

Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women

(2013) Jirong Long et al.   PLoS One

Rare Mutations in XRCC2 Increase the Risk of Breast Cancer

(2012) D.J. Park et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutation analysis of RAD51D in non-BRCA1/2 ovarian and breast cancer families

(2012) D J Osher et al.   BRITISH JOURNAL OF CANCER

GermlineRAD51Cmutations in ovarian cancer susceptibility

(2012) F Coulet et al.   CLINICAL GENETICS

Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families

(2012) Ana Osorio et al.   HUMAN MOLECULAR GENETICS

Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants

(2012) Claude Houdayer et al.   HUMAN MUTATION

Rare variants in XRCC2 as breast cancer susceptibility alleles: Table 1

(2012) Florentine S Hilbers et al.   JOURNAL OF MEDICAL GENETICS

Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

(2012) J. Chun et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

(2012) Nick Orr et al.   NATURE GENETICS

Germline RAD51C mutations confer susceptibility to ovarian cancer

(2012) Chey Loveday et al.   NATURE GENETICS

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility

(2011) Mikko Vuorela et al.   BREAST CANCER RESEARCH AND TREATMENT

Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer

(2011) K. N. Stevens et al.   CANCER RESEARCH

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium†

(2011) Jonine D. Figueroa et al.   HUMAN MOLECULAR GENETICS

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients

(2011) Ella R. Thompson et al.   HUMAN MUTATION

Association between the XRCC3 polymorphisms and breast cancer risk: meta-analysis based on case–control studies

(2011) Xiao-Feng He et al.   MOLECULAR BIOLOGY REPORTS

Germline mutations in RAD51D confer susceptibility to ovarian cancer

(2011) Chey Loveday et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

(2009) Gilles Thomas et al.   NATURE GENETICS