Immune mechanisms in heart failure

The extracellular matrix in myocardial injury, repair, and remodeling

(2017) Nikolaos G. Frangogiannis   JOURNAL OF CLINICAL INVESTIGATION

T cell costimulation blockade blunts pressure overload-induced heart failure

(2017) Marinos Kallikourdis et al.   Nature Communications

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease

(2017) Edmund J. Keliher et al.   Nature Communications

Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure

(2017) Giulio Cavalli et al.   Frontiers in Immunology

Decrease of circulating myeloid dendritic cells in patients with chronic heart failure

(2016) Rudin Pistulli et al.   ACTA CARDIOLOGICA

Anti-platelet drugs attenuate the expansion of circulating CD14highCD16+monocytes under pro-inflammatory conditions

(2016) Kerry Layne et al.   CARDIOVASCULAR RESEARCH

Temporal neutrophil polarization following myocardial infarction

(2016) Yonggang Ma et al.   CARDIOVASCULAR RESEARCH

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction

(2016) Sanjiv J. Shah et al.   CIRCULATION

Connecting heart failure with preserved ejection fraction and renal dysfunction: the role of endothelial dysfunction and inflammation

(2016) Jozine M. ter Maaten et al.   EUROPEAN JOURNAL OF HEART FAILURE

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN JOURNAL OF HEART FAILURE

Macrophages dictate the progression and manifestation of hypertensive heart disease

(2016) David Kain et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Alternatively activated macrophages determine repair of the infarcted adult murine heart

(2016) Manabu Shiraishi et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation as a Driver of Adverse Left Ventricular Remodeling After Acute Myocardial Infarction

(2016) Peter C. Westman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intercellular Adhesion Molecule 1 Regulates Left Ventricular Leukocyte Infiltration, Cardiac Remodeling, and Function in Pressure Overload–Induced Heart Failure

(2016) Ane M. Salvador et al.   Journal of the American Heart Association

Nonclassical Resident Macrophages Are Important Determinants in the Development of Myocardial Fibrosis

(2015) Alec Falkenham et al.   AMERICAN JOURNAL OF PATHOLOGY

Immune Cell and Other Noncardiomyocyte Regulation of Cardiac Hypertrophy and Remodeling

(2015) R. A. Frieler et al.   CIRCULATION

Exercise and the Cardiovascular System

(2015) Carl J. Lavie et al.   CIRCULATION RESEARCH

Innate Immunity and the Failing Heart

(2015) Douglas L. Mann   CIRCULATION RESEARCH

Role of Lymphocytes in Myocardial Injury, Healing, and Remodeling After Myocardial Infarction

(2015) U. Hofmann et al.   CIRCULATION RESEARCH

Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction?

(2015) Matthias Nahrendorf et al.   EUROPEAN HEART JOURNAL

The cellular immune system in the post-myocardial infarction repair process

(2015) Sam C. Latet et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Up-regulated TLR4 in cardiomyocytes exacerbates heart failure after long-term myocardial infarction

(2015) Li Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mitral valve disease—morphology and mechanisms

(2015) Robert A. Levine et al.   Nature Reviews Cardiology

Regulatory T cells in cardiovascular diseases

(2015) Xiao Meng et al.   Nature Reviews Cardiology

Molecular Imaging of the Chemokine Receptor CXCR4 After Acute Myocardial Infarction

(2015) James T. Thackeray et al.   JACC-Cardiovascular Imaging

Platelets in Inflammation and Atherogenesis

(2015) Henry M. Nording et al.   Frontiers in Immunology

Association between brain natriuretic peptide, markers of inflammation and the objective and subjective response to cardiac resynchronization therapy

(2014) Corline Brouwers et al.   BRAIN BEHAVIOR AND IMMUNITY

CD4 + T Cells Promote the Transition From Hypertrophy to Heart Failure During Chronic Pressure Overload

(2014) Fanny Laroumanie et al.   CIRCULATION

Characterizing the Inflammatory Tissue Response to Acute Myocardial Infarction by Clinical Multimodality Noninvasive Imaging

(2014) Tim Wollenweber et al.   Circulation-Cardiovascular Imaging

Changes and Prognostic Impact of Apoptotic and Inflammatory Cytokines in Patients Treated with Cardiac Resynchronization Therapy

(2013) Pavel Osmancik et al.   CARDIOLOGY

Targeting Interleukin-1 in Heart Disease

(2013) Benjamin W. Van Tassell et al.   CIRCULATION

Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

(2013) Stephane Heymans et al.   CIRCULATION

Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure

(2013) Mohamed Ameen Ismahil et al.   CIRCULATION RESEARCH

Decrease in dendritic cells in endomyocardial biopsies of human dilated cardiomyopathy

(2013) Rudin Pistulli et al.   EUROPEAN JOURNAL OF HEART FAILURE

Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target

(2013) N. Glezeva et al.   HEART FAILURE REVIEWS

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Asymptomatic Aortic Stenosis in the Elderly

(2013) Warren J. Manning   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IL-1 Induces Proinflammatory Leukocyte Infiltration and Regulates Fibroblast Phenotype in the Infarcted Myocardium

(2013) A. Saxena et al.   JOURNAL OF IMMUNOLOGY

Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction

(2013) Xiaoxiang Yan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Abdominal Contributions to Cardiorenal Dysfunction in Congestive Heart Failure

(2013) Frederik H. Verbrugge et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

(2013) Walter J. Paulus et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure

(2013) F. K. Swirski et al.   SCIENCE

Fibroblasts in post-infarction inflammation and cardiac repair

(2012) Wei Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel therapeutic approaches to post-infarction remodelling

(2012) D. Fraccarollo et al.   CARDIOVASCULAR RESEARCH

Immune Cell Modulation of Cardiac Remodeling

(2012) Richard M. Mortensen   CIRCULATION

Activation of CD4 + T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice

(2012) Ulrich Hofmann et al.   CIRCULATION

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

(2012) Suresh Kumar Verma et al.   CIRCULATION

CXC-Chemokine Receptor 4 Antagonist AMD3100 Promotes Cardiac Functional Recovery After Ischemia/Reperfusion Injury via Endothelial Nitric Oxide Synthase–Dependent Mechanism

(2012) Kentaro Jujo et al.   CIRCULATION

Increased Formation of Monocyte-Platelet Aggregates in Ischemic Heart Failure

(2012) Benjamin J. Wrigley et al.   Circulation-Heart Failure

Cardiac resynchronization therapy in patients with chronic heart failure is associated with anti-inflammatory and anti-remodeling effects

(2012) Adina Elena Stanciu et al.   CLINICAL BIOCHEMISTRY

Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction

(2012) Stefan Frantz et al.   FASEB JOURNAL

Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response

(2012) Anja M van der Laan et al.   HEART

Inflammatory activation following interruption of long-term cardiac resynchronization therapy

(2012) Andrzej Rubaj et al.   HEART AND VESSELS

Pressure overload-induced cardiac remodeling and dysfunction in the absence of interleukin 6 in mice

(2012) N Chin Lai et al.   LABORATORY INVESTIGATION

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure

(2012) Benjamin W. Van Tassell et al.   PLoS One

Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?

(2011) Patrick Collier et al.   EUROPEAN JOURNAL OF HEART FAILURE

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

(2011) Norimichi Koitabashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of Treatment on Exercise Tolerance, Cardiac Function, and Mortality in Heart Failure With Preserved Ejection Fraction

(2011) David J. Holland et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction

(2010) Rudolf A. de Boer et al.   ANNALS OF MEDICINE

Smad3 Signaling Critically Regulates Fibroblast Phenotype and Function in Healing Myocardial Infarction

(2010) Marcin Dobaczewski et al.   CIRCULATION RESEARCH

Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure

(2010) Anja Sandek et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inflammatory Markers and Incident Heart Failure Risk in Older Adults

(2010) Andreas Kalogeropoulos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction

(2010) K. Jujo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

Effects of Statin Therapy According to Plasma High-Sensitivity C-Reactive Protein Concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

(2009) John J.V. McMurray et al.   CIRCULATION

Divergent Tumor Necrosis Factor Receptor–Related Remodeling Responses in Heart Failure

(2009) Tariq Hamid et al.   CIRCULATION

Myeloid Differentiation Factor-88/Interleukin-1 Signaling Controls Cardiac Fibrosis and Heart Failure Progression in Inflammatory Dilated Cardiomyopathy

(2009) Przemyslaw Blyszczuk et al.   CIRCULATION RESEARCH

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

Cardiac Mast Cells Mediate Left Ventricular Fibrosis in the Hypertensive Rat Heart

(2009) Scott P. Levick et al.   HYPERTENSION

Extracellular matrix remodeling during the progression of volume overload-induced heart failure

(2009) Kirk R. Hutchinson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocarditis

(2009) Leslie T. Cooper   NEW ENGLAND JOURNAL OF MEDICINE

Myocardial repair/remodelling following infarction: roles of local factors

(2008) Y. Sun   CARDIOVASCULAR RESEARCH

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR

(2008) Prasanna Krishnamurthy et al.   CIRCULATION RESEARCH

Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a placebo-controlled randomised trial

(2008) Guillermo Torre-Amione et al.   LANCET

Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET