The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study

Translational insight into statin-induced muscle toxicity: from cell culture to clinical studies

(2014) Dhiaa A. Taha et al.   Translational Research

Simvastatin Effects on Skeletal Muscle

(2013) Steen Larsen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation

(2013) P. G. La Guardia et al.   Frontiers in Physiology

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

(2012) Steen Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins

(2012) P. Sirvent et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes

(2011) S. Larsen et al.   DIABETOLOGIA

Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a ‘mitohormesis’ mechanism involving reactive oxygen species and PGC-1

(2011) Jamal Bouitbir et al.   EUROPEAN HEART JOURNAL

Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes

(2011) Hyo-Bum Kwak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

Atorvastatin Causes Insulin Resistance and Increases Ambient Glycemia in Hypercholesterolemic Patients

(2010) Kwang Kon Koh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

(2010)   LANCET

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

(2009) Michael J. Knauer et al.   CIRCULATION RESEARCH

Decreased Ubiquinone Availability and Impaired Mitochondrial Cytochrome Oxidase Activity Associated With Statin Treatment

(2008) Andrew J. Duncan et al.   TOXICOLOGY MECHANISMS AND METHODS