Review
Oncology
Primoz Strojan, Ales Groselj, Gregor Sersa, Christina Caroline Plaschke, Jan B. Vermorken, Sandra Nuyts, Remco de Bree, Avraham Eisbruch, William M. Mendenhall, Robert Smee, Alfio Ferlito
Summary: Electrochemotherapy, based on reversible electroporation and intracellular accumulation of hydrophilic drug molecules, is considered an effective and safe treatment for tumors, including mucosal cancer of the head and neck. Limited experience with ECT in mucosal HNC due to poor accessibility of tumors highlights the need for further research to confirm its potential as a treatment option in selected patients.
Review
Otorhinolaryngology
Justin Yu, Justin Smith, Ravi Marwah, Oskar Edkins
Summary: This review aimed to determine the prevalence of return to work among head and neck cancer survivors and its impact on quality of life. The findings suggest that a majority of survivors are able to return to work and that this is associated with lower levels of anxiety and depressive symptoms.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Review
Medical Laboratory Technology
Vijaya Marakala
Summary: This study conducted a systematic review and meta-analysis on the diagnostic capabilities of biological markers in the plasma, serum, tissue, and saliva of patients with head and neck cancer. The results showed that combined biomarkers had higher diagnostic accuracy compared to individual biomarkers, but further studies are needed to validate these findings.
CLINICA CHIMICA ACTA
(2023)
Review
Oncology
Zsuzsanna Iyizoba-Ebozue, Robin Prestwich, Sarah Brown, Emma Hall, John Lilley, Matthew Lowe, David J. Thomson, Finbar Slevin, Florien Boele, Louise Murray
Summary: When radiotherapy is used in the treatment of head and neck cancers, the brain may also receive radiation, resulting in potential neurocognitive changes and affecting quality of life. However, there has been limited research on this topic. Most studies show that neurocognitive outcomes are worse in patients who received radiotherapy compared to the control group, particularly in memory and language domains. Magnetic Resonance Imaging may be useful in detecting early structural and functional changes that can indicate future neurocognitive changes. Neurocognitive impairment is associated with poorer quality of life. More high-quality and large-scale studies are needed to draw definitive conclusions.
RADIOTHERAPY AND ONCOLOGY
(2023)
Review
Medicine, General & Internal
Barbara Burgos-Mansilla, Noelia Galiano-Castillo, Mario Lozano-Lozano, Carolina Fernandez-Lao, Maria Lopez-Garzon, Manuel Arroyo-Morales
Summary: The study found that physical therapy modalities targeting Head and Neck Cancer survivors can effectively improve Quality of Life, with 12-week aerobic activity or PRT training being effective and safe. However, electrophysical agents did not yield significant results. Some articles had a high risk of bias, but exercise interventions were shown to have meaningful benefits for HNC survivors' QoL.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Oncology
Claire Leis, Anna E. Arthur, Xin Chen, Michael W. Greene, Andrew D. Fruge
Summary: Head and neck cancer patients are at risk of malnutrition during treatment. Nutrition interventions, including medical nutrition therapy and oral nutrition supplements, have shown positive outcomes in preventing weight loss and improving quality of life, nutrient intake, and treatment tolerance in these patients.
Review
Oncology
Claudia Zecena Morales, Karolina Lisy, Lachlan McDowell, Amanda Piper, Michael Jefford
Summary: This review examines the employment outcomes of head and neck cancer (HNC) survivors after treatment and identifies factors associated with their return to work (RTW). The proportion of HNC survivors who RTW varies significantly, ranging from 32% to 90%, with participants taking 3.6-11 months to RTW. Working in a professional role and having a supportive work environment are positively associated with RTW.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Sarah Thilges, Patricia Mumby, James Sinacore, Joseph Clark, Cheryl Czerlanis
Summary: Head and neck cancers (HNC) and their treatments can cause physical and functional impairment as well as psychological distress. This study aimed to improve the health-related quality of life of HNC patients through a cognitive behavioral intervention. The results showed that the intervention had a positive effect on the patients' self-efficacy, depressive symptoms, psychological symptoms, and overall quality of life.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Otorhinolaryngology
Kelsey A. Duckett, Mohamed Faisal Kassir, Shaun A. Nguyen, Emily A. Brennan, Bhishamjit S. Chera, Katherine R. Sterba, Chanita Hughes Halbert, Elizabeth G. Hill, Jessica Mccay, Sidharth V. Puram, Vlad C. Sandulache, Russel Kahmke, Salma Ramadan, Brian Nussenbaum, Anthony J. Alberg, Evan M. Graboyes
Summary: This study systematically reviews and synthesizes the literature on delays in initiating postoperative radiotherapy for HNSCC and finds that approximately half of the patients experience delays of more than 6 weeks. These data can be used to establish national benchmarks and assess progress in reducing delays.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Review
Immunology
Yuting Pu, Gangcai Zhu, Yimin Xu, Siyuan Zheng, Bin Tang, Huimei Huang, Irene X. Y. Wu, Donghai Huang, Yong Liu, Xin Zhang
Summary: The systematic review found that elevated activities of vitamin D by diet intake, genomic polymorphisms, or circulated 25-OHD may protect people from HNC and improve the prognosis of patients with HNC.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Oncology
Loren E. E. Smith, Barbara A. A. Murphy, Derek K. K. Smith
Summary: This review aimed to compile the available evidence on the prophylactic use of gabapentin in head and neck cancer patients. A systematic search identified 10 studies that met the inclusion criteria, which showed that prophylactic gabapentin appears to be a promising treatment option for preventing pain, reducing opioids, and reducing weight loss. However, the studies available are small and have a substantial risk of bias.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Nauman H. Malik, Manjula Maganti, Maurene McQuestion, Michael C. Tjong, Dana Keilty, Eric Monteiro, Shao Hui Huang, Raymond Woo-Jun Jang, Andrea Gomes, Joanne Pun, Jolie Ringash
Summary: The study found that attending a pre-treatment psychoeducational intervention was associated with higher survival rates and lower recurrence rates in patients receiving radiotherapy for head and neck cancers. Multivariable analysis showed that non-attendees had unfavorable survival and recurrence outcomes. Furthermore, attendees had a lower frequency of treatment-related issues compared to non-attendees.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Oncology
Cherith J. Semple, Gerry McKenna, Roisin Parahoo, Simon N. Rogers, Ylva Tiblom Ehrsson
Summary: This article conducted a systematic review on the quality of life of older head and neck cancer patients. The results showed that older patients experience significant impacts on their quality of life due to the cancer, which also affects their treatment decision-making and post-treatment support.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2023)
Review
Medicine, General & Internal
Matthijs In 't Veld, Derk H. J. Jager, Chayenne N. Chhangur, Kirsten A. Ziesemer, Frank K. J. Leusink, Engelbert A. J. M. Schulten
Summary: Oral-functioning impairment can negatively affect the quality of life of head and neck cancer patients after radiotherapy. This scoping review proposes a definition for oral functioning in these patients and identifies questionnaires for assessing patient-reported oral functioning. The common denominators for oral functioning were found to be chewing, speaking, and swallowing. Based on the included studies, the VHNSS 2.0 questionnaire is recommended for assessing oral functioning in these patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Otorhinolaryngology
Joep A. F. van Rooij, Jantien Roubos, Noelle J. M. C. Vrancken Peeters, Bianca F. M. Rijken, Eveline M. L. Corten, Marc A. M. Mureau
Summary: The current literature on reconstruction after head and neck cancer mainly focuses on short-term patient-reported outcomes (PROs), but more knowledge is needed on long-term consequences. A systematic review of 30 studies with 2358 patients revealed that reconstructive surgery generally leads to diminished oral function, worsened by radiotherapy. Patients experience anxiety and fear of cancer recurrence, but there is a progressive decrease in pain over time with some flaps having more favorable health-related quality of life (HRQoL) outcomes. Age and bony tumor involvement are not associated with postoperative HRQoL.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Critical Care Medicine
Catherine Tyerman, Laura Shepherd, Danielle De Boos, Anna Tickle
Summary: This study found that burn patients may have positive psychological experiences through medical tattooing, which allows them to regain a sense of normality and acceptance in society. However, there is also a conflicting narrative between the pressure to conform to certain appearance expectations and an internal conflict. Support and further research are warranted to determine the psychological impact of medical tattooing on burn patients.
Article
Psychology, Clinical
Sam Malins, Nima Moghaddam, Richard Morriss, Thomas Schroder, Paula Brown, Naomi Boycott
Summary: This study compared the predictive validity of patient, therapist and in-session ratings of motivational factors in rCBT for SHA. Results showed that when patients were more actively engaged in discussing positive changes during session two, improvements in health anxiety and secondary outcomes were greater. Therapist assessments of client confidence and motivation predicted all secondary outcomes.
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY
(2022)
Article
Psychology, Clinical
Kate Shepherd, Beth Pritty, Anna Tickle, Nima Moghaddam
Summary: The misuse of substances is often sustained by both physical and psychological factors. In the UK, individuals who misuse substances are frequently excluded from mental health services, leading to unaddressed underlying difficulties. Acceptance and Commitment Therapy (ACT) aims to reduce emotional avoidance and has shown positive effects in managing substance misuse.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Article
Psychology, Developmental
Hannah Legg, Anna Tickle, Alinda Gillott, Sarah Wilde
Summary: There is a growing trend of adult diagnosis of Autism Spectrum Disorder (ASD), and lack of post-diagnostic support may disrupt the sense-making process. This study interviewed 11 parents of recently diagnosed adults and found that the new knowledge of diagnosis led to changes in attributions, interactions, and relationships, but also resulted in unmet emotional and relational support needs.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Review
Psychology, Clinical
Aliya Zamir, Anna Tickle, Rachel Sabin-Farrell
Summary: This systematic review examines the prevalence and choices of disclosure of psychological distress among mental health professionals in the workplace. The findings suggest that professionals are less likely to disclose their distress at work compared to social circles, and they often have negative experiences when they do. The fear of stigma is a major barrier to disclosure. Factors affecting the level of disclosure include the recipient, trust, quality of supervision, conceptualization of distress, and type of problem. Some professionals find disclosure to be valuable. However, the limitations of the included studies call for caution in interpreting the conclusions. Further research is needed to explore the complexities of disclosure choices for mental health professionals.
JOURNAL OF CLINICAL PSYCHOLOGY
(2022)
Article
Psychiatry
Laura Edwards, Rachel Sabin-Farrell, Roger Bretherton, David M. Gresswell, Anna Tickle
Summary: This study explored clergy experiences of role-demands, coping, and support. The findings showed that clergy members commonly utilize religious coping skills, specifically maintaining a stable relationship with God. The study also identified barriers to support within and outside of the church. These findings support previous research and suggest the importance of considering spirituality in future studies and interventions. Additionally, practical and cultural changes within the church could help reduce barriers to support for clergy.
MENTAL HEALTH RELIGION & CULTURE
(2022)
Article
Environmental Sciences
Nurfarahin Musa, Nicholas Tze Ping Pang, Assis Kamu, Chong Mun Ho, Cerith Waters, Jennifer Berrett, Nima Moghaddam, Walton Wider
Summary: This study developed a psychometrically sound instrument called CompACT to assess psychological flexibility and tested its validity and reliability in the Malay version. The results showed that the Malay version of the CompACT Scale demonstrated good internal consistency, convergent validity, and reliability, making it a reliable tool to assess psychological flexibility in clinical and research settings.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Education, Special
Katie Marlow, Thomas Schroder, Anna Tickle, Jess Renton
Summary: This study aimed to develop an adapted version of Narrative Exposure Therapy (NET) for adults with mild intellectual disabilities (IDNET). Professionals were optimistic about IDNET, but issues regarding its delivery require further exploration in practice.
BRITISH JOURNAL OF LEARNING DISABILITIES
(2023)
Article
Psychology, Clinical
Amelia Staton, David Dawson, Nima Moghaddam, Barbara McGrath
Summary: This study evaluated the sensitivity and specificity of the Social Communication Questionnaire (SCQ) in a Children and Adolescent Mental Health Services. The results showed that the SCQ had a sensitivity of 80% and a specificity of 25.7%, indicating low diagnostic accuracy.
CLINICAL CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Editorial Material
Environmental Sciences
Duncan French, David L. Dawson, Nima Golijani-Moghaddam
Summary: No one can determine how we should feel about environmental harm, whether it be upset, distress, or existential angst. This commentary emphasizes the need for conscious reflection on how environmental harm affects our scholarship and the importance of taking proactive steps to improve our mental health and self-care.
JOURNAL OF ENVIRONMENTAL LAW
(2023)
Article
Psychology, Clinical
Emma Victoria Garner, Nima Golijani-Moghaddam, Rachel Sabin -Farrell
Summary: This study aimed to examine whether psychological flexibility can predict the levels of compassion fatigue and compassion satisfaction in newly qualified psychological therapy practitioners. The study found that higher levels of psychological flexibility were associated with higher levels of compassion satisfaction and lower levels of burnout and secondary traumatic stress. The findings suggest a predictive association between psychological flexibility and professional quality of life outcomes for psychological therapy practitioners.
JOURNAL OF CONTEXTUAL BEHAVIORAL SCIENCE
(2023)
Article
Psychology, Clinical
Amie Robinson, Danielle De Boos, Nima Moghaddam
Summary: This study investigated the effectiveness and acceptability of acceptance and commitment therapy (ACT) for people with dementia, considering carer-supported, remote delivery and necessary therapy adaptations. The results showed that ACT had positive effects in reducing psychological distress and helping carers meet the needs of their loved ones. Future research should focus on optimizing ACT delivery in this population.
COUNSELLING & PSYCHOTHERAPY RESEARCH
(2023)
Letter
Dentistry, Oral Surgery & Medicine
Helen R. Chapman, Nima Moghaddam, Nick Kirby-Turner
ACTA ODONTOLOGICA SCANDINAVICA
(2023)
Article
Psychology, Clinical
Amelia Staton, David Dawson, Hannah Merdian, Anna Tickle, Tammy Walker
Summary: Individuals with a diagnosis of FND experience stigma in psychological services, highlighting the need for increased training to challenge this stigma.
PSYCHOLOGY AND PSYCHOTHERAPY-THEORY RESEARCH AND PRACTICE
(2023)
Article
Medicine, Research & Experimental
Nima Golijani-Moghaddam, David L. Dawson, Nikos Evangelou, James Turton, Annie Hawton, Graham R. Law, Bryan Roche, Elise Rowan, Rupert Burge, Alexandra C. Frost, Roshan das Nair
Summary: Cognitive deficits are common in people with MS, with up to 70% experiencing difficulties in higher-level brain functions, and the lack of effective interventions exacerbates burden on services and impacts quality of life. The planned research aims to develop and test an online cognitive rehabilitation program (SMART) for improving cognitive functioning in people with MS, filling an existing evidence gap.
PILOT AND FEASIBILITY STUDIES
(2022)
