Article
Engineering, Environmental
Naganagouda Goudar, Vinayak N. Vanjeri, Deepak Kasai, Gangadhar Gouripur, Ravindra B. Malabadi, Saraswati P. Masti, Ravindra B. Chougale
Summary: The study investigated the influence of Zinc Oxide nanoparticles on the physicochemical properties of poly(vinyl alcohol)/Spathodea campanulata bud fluid matrix, showing improved tensile strength, glass transition temperature, thermal stability, and water vapor transmission rate. The nanocomposite films exhibited good antibacterial activity and preservation capacity, making them a potential alternative to nonbiodegradable packaging materials.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Ecology
Sebastien Larrue, Jean-Luc Baray, Julien Chadeyron, Jean-Yves Meyer, Lucas Mazal, Curtis C. C. Daehler, Boris Fumanal
Summary: Using a three-dimensional kinematic trajectory model, researchers found that wind-dispersed seeds of the invasive tree Spathodea campanulata could naturally spread to most of the Society Islands, including reaching distances of up to 1364 km.
ECOLOGICAL APPLICATIONS
(2023)
Article
Plant Sciences
Herbert Kolodziej
Summary: The study identifies newbouldiosides D-F as minor phenylethanoid glycosides and extends the series of naturally occurring flavonoids with unique structural elements. These compounds, including the sinapoyl element, represent novel additions to the chemical diversity of plant metabolites.
Article
Biochemistry & Molecular Biology
Lukasz Swiatek, Elwira Sieniawska, Kouadio Ibrahime Sinan, Gokhan Zengin, Abdullahi Ibrahim Uba, Kouadio Bene, Magdalena Maciejewska-Turska, Barbara Rajtar, Malgorzata Polz-Dacewicz, Abdurrahman Aktumsek
Summary: Spathodea campanulata is an important medicinal plant with traditional uses. This study determined the chemical profiles and biological effects of its leaf and stem bark extracts. The extracts showed antioxidant, enzyme inhibitory, antineoplastic, and antiviral activities.
Article
Biochemistry & Molecular Biology
Jitendra Bajaj, Jaya Dwivedi, Ram Sahu, Vivek Dave, Kanika Verma, Sushil Joshi, Bhawana Sati, Swapnil Sharma, Veronique Seidel, Abhay Prakash Mishra
Summary: The methanol extract of Spathodea campanulata flowers exhibited dose-dependent antidepressant activity in mice, significantly reducing immobility period in forced swim and tail suspension tests. The extract also decreased lithium chloride-induced head twitches and locomotor activity. Analysis of the extract revealed the presence of specific compounds with high binding affinity for MAO-A enzyme, suggesting potential for novel antidepressant drug development.
CELLULAR AND MOLECULAR BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Tsutomu Okuno, Masami Kojima, Nailia Hasanova, Yoshihisa Ishiba, David H. Sliney
Summary: Studies have shown that exposure to IR can cause acute changes in the crystalline lens, potentially leading to cataracts. By exposing rabbit eyes to IR at different irradiance levels for varying durations, the threshold irradiance to cause acute lens opacification was determined.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Kang Du, Hongyu Guan, Yunyun Zhang, Yuxiu Ding, Decai Wang
Summary: Cataract knowledge is low among older adults in rural China, and there is a low utilization of eye care services. Understanding cataract knowledge is associated with eye care utilization.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Cell Biology
Manuel Ruiss, Oliver Findl, Martin Kronschlaeger
Summary: Cataract is a leading cause of blindness globally, and surgery is currently the only treatment option. However, complications and limited access to ophthalmic care may arise. With a growing and aging population, there will be an increase in cataract prevalence, presenting a challenge to society. As oxidative stress is a major pathological process in cataract formation, antioxidant supplementation may be a strategy to delay or prevent its progression. Caffeine, a widely consumed antioxidant, shows potential for preventing cataract.
AGEING RESEARCH REVIEWS
(2022)
Article
Cell Biology
Matthieu Duot, Roselyne Viel, Justine Viet, Catherine Le Goff-Gaillard, Luc Paillard, Salil A. Lachke, Carole Gautier-Courteille, David Reboutier
Summary: This study successfully generated lens organoids that mimic the properties and organization of the lens tissue, providing a new research tool for studying lens biology and cataracts, as well as for drug screening.
Article
Ophthalmology
Ganesh-Babu Balu Subburaman, Anitha Gunasekaran, Sivakumar Chandrashekaran, Ravilla D. Ravindran, Frits van Merode, Logesh Balakrishnan, Thulasiraj Ravilla, Sachin Gupta
Summary: This study aimed to compare the post-operative visual outcomes of cataract surgeries between a tertiary and secondary centre at Aravind Eye Hospitals in Tamil Nadu, India. The retrospective cross-sectional study analyzed cataract surgeries at the two centres in 2021. The results showed that the tertiary centre had higher rates of post-operative complications and operated on more advanced cataract cases.
Article
Multidisciplinary Sciences
Jean Emmanuel Mbosso Teinkela, Hassan Oumarou, Xavier Siwe Noundou, Franck Meyer, Veronique Megalizzi, Heinrich C. Hoppe, Rui Werner Macedo Krause, Rene Wintjens
Summary: This study investigated the antiplasmodial and antiproliferative activities of Spathodea campanulata flowers and assessed the acute toxicity of its aqueous fraction. The results showed that the extract and fractions of the flower have potential antimalarial and anticancer effects. The aqueous fraction was found to be non-toxic at tested doses. These findings support the traditional use of Spathodea campanulata in herbal medicine.
SCIENTIFIC AFRICAN
(2023)
Review
Ophthalmology
Rita Mencucci, Roberto Vignapiano, Pierangela Rubino, Eleonora Favuzza, Emilia Cantera, Pasquale Aragona, Maurizio Rolando
Summary: The incidence and prevalence of dry eye disease after cataract surgery are often underestimated, affecting patients' quality of life. It is crucial to assess the ocular surface both before and after surgery to reduce the risk of postoperative dry eye and improve surgical outcomes.
OPHTHALMOLOGY AND THERAPY
(2021)
Editorial Material
Ophthalmology
Abhinav Golla, Angela Chen, Victoria L. Tseng, Samuel Y. Lee, Deyu Pan, Fei Yu, Anne L. Coleman
Summary: According to the survey data of American adults, current use of e-cigarettes is associated with visual impairment, independent of traditional cigarette use.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Azza Dammak, Cristina Pastrana, Alba Martin-Gil, Carlos Carpena-Torres, Assumpta Peral Cerda, Mirjam Simovart, Pilar Alarma, Fernando Huete-Toral, Gonzalo Carracedo
Summary: The eye is constantly exposed to solar radiations and vulnerable to reactive oxygen species, leading to biomolecular modifications in ocular diseases. Anterior eye segment injury originates from the imbalance of pro-oxidant/antioxidant levels, resulting in increased oxidative damage. Oxidative stress is related to various ocular diseases, such as dry eye, keratoconus, uveitis, and cataract, through mechanisms like inflammation and mitochondrial dysfunction. Biomarkers offer potential for predictive diagnostics of eye diseases. This review analyzes oxidative stress, inflammation, and the importance of biomarkers in anterior ocular diseases.
Article
Pharmacology & Pharmacy
Anita Wagh, Santosh Butle, Dipak Raut
Summary: This study isolated and identified three compounds from the chloroform extract of Spathodea campanulata leaves. These compounds exhibited dose-dependent cytotoxicity and antiproliferative activity, although their effectiveness was lower compared to the positive control drug Adriamycin. Additionally, this study reported the first isolation and identification of octadecenamide and umbelliferone from the leaves of S. campanulata.
FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Medicinal
Suthananda N. Sunassee, Clinton G. L. Veale, Nelusha Shunmoogam-Gounden, Omalaja Osoniyi, Denver T. Hendricks, Mino R. Caira, Jo-Anne de la Mare, Adrienne L. Edkins, Antonio V. Pinto, Eufranio N. da Silva Junior, Michael T. Davies-Coleman
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2013)
Article
Plant Sciences
Albert W. W. van Wyk, Christopher A. Gray, Catherine E. Whibley, Omolaja Osoniyi, Denver T. Hendricks, Mino R. Caira, Michael T. Davies-Coleman
JOURNAL OF NATURAL PRODUCTS
(2008)
Article
Biochemistry & Molecular Biology
Emeka E. Okoro, Rukesh Maharjan, Almas Jabeen, Malik Shoaib Ahmad, Mudassir Azhar, Nuzhat Shehla, Wajid Zaman, Sidrah Shams, Omolaja R. Osoniyi, Funmilayo D. Onajobi, M. Iqbal Choudhary
Summary: Phytochemical studies on the root of Abrus precatorius Linn. identified several new and known abruquinones, showing potential anticancer and anti-inflammatory activities, particularly demonstrating significant cytotoxicity and inhibition in oral, colon, and lung cancer cell lines. These findings suggest the isoflavanquinones from A. precatorius roots as promising candidates for further research in cancer treatment.
Article
Immunology
Adetunji Samuel Adesina, Akinlabi Oyeyiola, Adeoba Obadare, Joseph Igbokwe, Chukwuyem Abejegah, Patience Akhilomen, Umaru Bangura, Danny Asogun, Ekaete Tobin, Olufemi Ayodeji, Omolaja Osoniyi, Chris Davis, Emma C. Thomson, Meike Pahlmann, Stephan Guenther, Elisabeth Fichet-Calvet, Ayodeji Olayemi
Summary: We compared the genetic sequences of the Lassa virus obtained from rodents in different localities in Edo and Ondo States, Nigeria. We found different clades of the virus in different areas, suggesting east-west virus migration within the region. The amplification of the virus in certain localities, the spread of rodent-borne variants in larger towns, and the exchange of the virus between different rodent species pose a constant zoonotic threat in the Lassa fever belt.
EMERGING MICROBES & INFECTIONS
(2023)
Article
Chemistry, Medicinal
Emeka E. Okoro, Malik Shoaib Ahmad, Rukesh Maharjan, Majid Khan, Zaid A. Sherwani, Zaheer Ul-Haq, Samuel E. Ugheighele, Ochuko L. Erukainure, Omolaja R. Osoniyi, Funmilayo D. Onajobi, M. Iqbal Choudhary
Summary: This study isolated four abruquinones from Abrus precatorius and evaluated their therapeutic effects. The compounds demonstrated significant antibacterial, antiurease, and anticancer activities, suggesting their potential as candidates for drug development.
JOURNAL OF BIOLOGICALLY ACTIVE PRODUCTS FROM NATURE
(2022)
Article
Medicine, General & Internal
Abraham Abbey Paul, Queensley Adesuwa Eghianruwa, Olayemi Grace Oparinde, Adetunji Samuel Adesina, Omolaja Osoniyi
Summary: This study investigates the ACE inhibitory and DPPH radical scavenging activities of two species of the Nigerian periwinkles: Pachymelania aurita and Tympanotonus fuscatus. The results suggest the potential health benefits of consuming T. fuscatus var. radula and P. aurita in health maintenance, due to their relatively high activities in ACE inhibition and DPPH radical scavenging.
INTERNATIONAL JOURNAL OF APPLIED AND BASIC MEDICAL RESEARCH
(2021)
Article
Nutrition & Dietetics
Rachael Aderonke Ayo-Lawal, Omolaja Osoniyi, Nicole Remaliah Samantha Sibuyi, Mervin Meyer, Okobi Ekpo
Summary: The aqueous extract from fermented Citrullus vulgaris seeds shows potential anti-cancer properties by inhibiting cancer cell growth and inducing apoptosis.
JOURNAL OF DIETARY SUPPLEMENTS
(2021)
Article
Clinical Neurology
Queensley Eghianruwa, Omolaja Osoniyi, Naomi Maina, Sabina Wachira, Mabel Imbuga
JOURNAL OF PAIN RESEARCH
(2020)
Article
Entomology
I. J. Abulude, I. G. Adio, F. Ogunlola, I. T. Odejide, O. J. Soyelu, R. O. Osoniyi
INTERNATIONAL JOURNAL OF TROPICAL INSECT SCIENCE
(2020)
Article
Education, Scientific Disciplines
Iruka N. Okeke, Chinedum P. Babalola, Denis K. Byarugaba, Abdoulaye Djimde, Omolaja R. Osoniyi
CBE-LIFE SCIENCES EDUCATION
(2017)
Article
Chemistry, Multidisciplinary
Suthananda N. Sunassee, Albert W. W. Van Wyk, Ornolaja Osoniyi, Denver T. Hendricks, Michael T. Davies-Coleman
JOURNAL OF CHEMICAL RESEARCH
(2007)
Article
Chemistry, Applied
P Siddhuraju, O Osoniyi, HPS Makkar, K Becker
Article
Plant Sciences
O Osoniyi, F Onajobi
JOURNAL OF ETHNOPHARMACOLOGY
(2003)
Article
Physics, Multidisciplinary
JO Ojo, RO Osoniyi, AO Aboderin
CZECHOSLOVAK JOURNAL OF PHYSICS
(2003)