Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2 +/Q390X Dravet syndrome mice

Altered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2+/Q390X mice associated with epileptic encephalopathy

(2016) Geqing Xia et al.   EPILEPSY RESEARCH

Differential molecular and behavioural alterations in mouse models ofGABRG2haploinsufficiency versus dominant negative mutations associated with human epilepsy

(2016) Timothy A. Warner et al.   HUMAN MOLECULAR GENETICS

The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration

(2015) Jing-Qiong Kang et al.   NATURE NEUROSCIENCE

Antiepileptogenesis in humans

(2014) Eugen Trinka et al.   CURRENT OPINION IN NEUROLOGY

Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin

(2013) Evan A. Thomas et al.   EPILEPSIA

Multiple molecular mechanisms for a single GABAA mutation in epilepsy

(2013) C. A. Reid et al.   NEUROLOGY

Evidence-based review on the natural history of the epilepsies

(2012) Dieter Schmidt et al.   CURRENT OPINION IN NEUROLOGY

mRNA surveillance and endoplasmic reticulum quality control processes alter biogenesis of mutant GABAAreceptor subunits associated with genetic epilepsies

(2012) Robert L. Macdonald et al.   EPILEPSIA

The Intronic GABRG2 Mutation, IVS6+2T->G, Associated with Childhood Absence Epilepsy Altered Subunit mRNA Intron Splicing, Activated Nonsense-Mediated Decay, and Produced a Stable Truncated  2 Subunit

(2012) M. Tian et al.   JOURNAL OF NEUROSCIENCE

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Restoration of Hearing in the VGLUT3 Knockout Mouse Using Virally Mediated Gene Therapy

(2012) Omar Akil et al.   NEURON

Optogenetic and Potassium Channel Gene Therapy in a Rodent Model of Focal Neocortical Epilepsy

(2012) R. C. Wykes et al.   Science Translational Medicine

Hypoxia-Induced Neonatal Seizures Diminish Silent Synapses and Long-Term Potentiation in Hippocampal CA1 Neurons

(2011) C. Zhou et al.   JOURNAL OF NEUROSCIENCE

Slow Degradation and Aggregation In Vitro of Mutant GABAA Receptor  2(Q351X) Subunits Associated with Epilepsy

(2010) J.-Q. Kang et al.   JOURNAL OF NEUROSCIENCE

The GABRG2 Mutation, Q351X, Associated with Generalized Epilepsy with Febrile Seizures Plus, Has Both Loss of Function and Dominant-Negative Suppression

(2009) J.-Q. Kang et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent development of inhibitory synapses and innervation pattern: role of GABA signalling and beyond

(2009) Z. Josh Huang   JOURNAL OF PHYSIOLOGY-LONDON

Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy?

(2009) Mark P. Beenhakker et al.   NEURON

A revised Racine's scale for PTZ-induced seizures in rats

(2009) Annika Lüttjohann et al.   PHYSIOLOGY & BEHAVIOR

A gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures

(2009) C. M. Schofield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice

(2008) D. G.M. Jugloff et al.   HUMAN MOLECULAR GENETICS

Molecular Pathology of Genetic Epilepsies Associated with GABAAReceptor Subunit Mutations

(2008) Robert L. Macdonald et al.   Epilepsy Currents