Article
Chemistry, Multidisciplinary
Lingkai Kong, Jieru Meng, Wenyue Tian, Jiazheng Liu, Xueping Hu, Zhi-Hong Jiang, Wei Zhang, Yanzhong Li, Li-Ping Bai
Summary: An efficient approach for the synthesis of 1,2-diaryl diketones was developed from readily available alpha-methylene ketones by catalysis of I-2. In the same oxidation system, a novel one-pot procedure was established for the construction of antiviral and anticancer quinoxalines, showing good functional group tolerance with moderate to excellent yields. The synthesized compounds exhibited inhibitory effects on viral entry and cytotoxicity against cancer cells.
Article
Chemistry, Physical
Fereshte Hassanzadeh-Afruzi, Mohammad Mehdi Salehi, Golnaz Heidari, Ali Maleki, Ehsan Nazarzadeh Zare
Summary: This study describes a catalytic methodology for the efficient synthesis of pyrazolopyrazole derivatives using an environmentally friendly heterogeneous catalyst, which also demonstrates reusability and stability.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Applied
Frank Sznaider, Carlos A. Stortz, Ana M. Rojas, Diego A. Navarro
Summary: Traditionally, Brea gum obtained from the cuts made in the trunk and branches of Cercidium praecox tree is used as a substitute for gum Arabic in regions of Argentina. The rheological performance of purified Brea gum in water was evaluated and it showed higher initial thickening and pseudoplastic behavior compared to gum Arabic.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Multidisciplinary
Yuan-Yuan Cheng, Ji-Xin Yu, Tao Lei, Hong-Yu Hou, Bin Chen, Chen-Ho Tung, Li-Zhu Wu
Summary: This study presents the first example of 1,2-dicarbonylation of alkenes by photocatalysis, achieving unsymmetric 1,4-dicarbonylation by tuning the reductive and electrophilic ability of the acyl precursor. The metal-free, redox-neutral and regioselective reaction shows great potential in biomolecular and drug molecular derivatization.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Agricultural Engineering
Asmaa Al-Hamayda, Basim Abu-Jdayil, Mutamed Ayash, Joy Tannous
Summary: Natural gums are commonly used in various industries as stabilizers, thickeners, gelling agents, and emulsifiers. They can also act as carriers for food additives and have good barrier characteristics. Microencapsulation, especially spray drying, is an effective technique for improving the dispersion of bioactive substances in food. Arabic gum is an effective and safe antimicrobial and antioxidant additive in food, but its utility in the industrial encapsulation process is currently limited.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Physical
Changjun Liu, Huiling Hu, Chaojie Zhu, Wenqian Fu, Lei Zhang, Li Liu, Tiandi Tang
Summary: 1,2-Diketones play an essential role in natural products and bioactive molecules. The transformation of 1,2-diarylalkynes to 1,2-diketones can be achieved efficiently using Pd/HMZSM-5 catalyst without the need for additives.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Organic
Cheng Wang, Biao Liu, Zeyu Shao, Junqi Zhou, Andong Shao, Liang-Hua Zou, Jian Wen
Summary: A procedure for the mild synthesis of 1,2-diamines without the need for a catalyst and oxidizing reagent has been developed. This method demonstrated practicality through one-pot synthesis, scale-up reaction, and transformation of products. Mechanistic studies revealed the crucial role of aziridine formation in this diamination process.
Article
Chemistry, Applied
Jiawei Lin, Zhiming Wang, Hecheng Meng, Xiaoming Guo
Summary: This study improved the emulsification properties of gum arabic by crosslinking it with genipin, resulting in enhanced emulsifying stability and decreased dosage of emulsifier. The genipin-crosslinked gum arabic showed larger molecular weight and more compact conformation, leading to more stable emulsions even after sterilization or prolonged storage at elevated temperatures.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Organic
Yali Liu, Yu Wei, Zhen Yang, Yang Li, Yan Liu, Ping Liu
Summary: In this study, a successful C3-H direct iodination reaction was reported for the synthesis of novel 3-iodopyrrolo[1,2-a]quinoxaline derivatives, with significant promotion of selectivity and conversion by a catalytic amount of p-toluenesulfonic acid. The reaction can be scaled up to gram level, and the iodinated products can be further transformed into biologically active compounds through palladium-catalyzed coupling reactions.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Zhenyu Li, Ling Zhang, Chunling Mao, Zhiming Song, Xinxin Li, Chun Liu
Summary: This study evaluated composite gels prepared with konjac glucomannan (KGM) and gum arabic (GA) using various analytical methods, revealing gel stratification at certain concentrations, changes in microstructure with GA concentration, and increases in water solubility and water absorption with higher GA concentrations. Rheological analysis showed the gels to be non-Newtonian pseudoplastic fluids with different deformation characteristics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Medicinal
Cindy Patinote, Carine Deleuze-Masquefa, Kamel Hadj Kaddour, Laure-Anais Vincent, Romain Larive, Zahraa Zghaib, Jean-Francois Guichou, Mona Diab Assaf, Pierre Cuq, Pierre-Antoine Bonnet
Summary: Melanoma, the most aggressive skin cancer, causes several thousand deaths each year, posing a significant public health concern. New compounds based on specific structures show potential therapeutic effects for melanoma, demonstrating interesting cytotoxic activity in vitro.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Polymer Science
Rizwan Ullah, Nadia Khan, Rozina Khattak, Mehtab Khan, Muhammad Sufaid Khan, Omar M. Ali
Summary: The current research focused on the super capacitive behavior of organic conducting polymer, i.e., polypyrrole (PPy) and its composites with gum arabic (GA). The synthesized composites material showed high thermal stability and compact morphology. The electrochemical properties of the composites exhibited impressive specific capacitance and high energy density.
Article
Chemistry, Organic
Di Hao, Zhen Yang, Yali Liu, Yang Li, Chuntian Li, Yanlong Gu, Luigi Vaccaro, Jichang Liu, Ping Liu
Summary: An efficient Pd-catalyzed direct C-H arylation of pyrrolo[1,2-a]quinoxalines with aryl iodides has been developed, providing a selective route to a series of 1-arylated and 1,3-diarylated pyrrolo[1,2-a]quinoxalines with good yields. The method features broad substrate scope, good functional group tolerance, and gram-scale synthesis capability. Additionally, C3-thiocyanation of the arylated product has been achieved, indicating potential applications in organic synthesis and medicinal chemistry.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Jie Cao, Daqi Lv, Fei Yu, Mong-Feng Chiou, Yajun Li, Hongli Bao
Summary: The vicinal diamine motif is important in natural products, drug design, and organic synthesis, and developing methods for synthesizing vicinal diamines has long been of interest. This study reports on a regioselective intermolecular three-component vicinal diamination reaction using styrenes, acetonitrile, and azodicarboxylates. The diamination products can be obtained in moderate to excellent yields via the Ritter reaction, and synthetic applications and theoretical studies of this reaction have been conducted.
Article
Chemistry, Multidisciplinary
Anthony Aimon, Mark J. Dow, Abigail R. Hanby, Ephraim A. Okolo, Christopher M. Pask, Adam Nelson, Stephen P. Marsden
Summary: The stereocontrolled synthesis of complex spirotricyclic systems containing an embedded syn-1,2-diaminocyclohexane unit is achieved through a dearomatising oxidation of phenols bearing pendant ureas capable of acting as double nucleophiles. The resultant products possess rich functionality suitable for the synthesis of potentially bioactive compounds.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Elaheh Babaei, Bi Bi Fatemeh Mirjalili
Summary: This method utilizes nano-Al2O3/BF3/Fe3O4 catalyst in water at room temperature to synthesize 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines. The catalyst can be easily removed from the reaction mixture using an external magnet and shows good reusability without significant loss of activity. The synthesized 1,3-oxazine compounds were characterized by various methods and the method is environmentally friendly with excellent yields.
POLYCYCLIC AROMATIC COMPOUNDS
(2021)
Article
Chemistry, Organic
Nasrin Safajoo, Bi Bi Fatemah Mirjalili, Abdolhamid Bamoniri
Summary: The bio-based magnetic nano-catalyst Fe3O4@NCs/Cu(II) was prepared by adding CuCl2 to Fe3O4@NCs in alkaline medium, and successfully used for the synthesis of a series of indenopyrido [2,3-d] pyrimidines in ethanol. The efficient and eco-friendly catalyst showed good yields, short reaction times, and easy work-up, making it suitable for reuse in subsequent experiments.
POLYCYCLIC AROMATIC COMPOUNDS
(2021)
Article
Chemistry, Organic
Mahnaz Mahmoodi Fard Chegeni, Abdolhamid Bamoniri, Bi Bi Fatemeh Mirjalili
Summary: A four-component reaction of aromatic aldehydes, phthalic anhydride, hydrazine monohydrate and dimedone has been achieved in the presence of nano-gamma-Al2O3/BFn/Fe3O4 as a highly effective heterogeneous catalyst to produce 2H-indazolo[2,1-b]phthalazine triones. Atom economy, low catalyst loading, reusable catalyst, applicability to a wide range of substrates and high yields of products are some important features of this protocol.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Organic
Sahar Saadat Hosseinikhah, Bi Bi Fatemeh Mirjalili
Summary: A bio-based magnetic nano-catalyst Fe3O4@nano-cellulose/Sb(V) was synthesized and its structure was confirmed by various analysis methods. The catalyst exhibited excellent catalytic ability under solvent-free conditions, achieving high yields and purity of the target compounds. It can be easily recovered and reused multiple times without significant loss of efficiency.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Organic
Maryam Mehravar, Bi Bi Fatameh Mirjalili, Elaheh Babaei, Abdolhamid Bamoniri
Summary: In this study, a new nanocomposite, nano-AlPO4/Ti(IV) (NAPT), was prepared and characterized for the synthesis of dihydropyrano[2,3-c]pyrazole (DHPP) derivatives. The method offers a simple work-up, high product yields, short reaction times, and the use of a low-cost catalyst.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Review
Endocrinology & Metabolism
Mohammad Hassan Houshdar Tehrani, Mohammadreza Gholibeikian, Abdolhamid Bamoniri, Bi Bi Fatemeh Mirjalili
Summary: Bioactive peptides show potential for cancer treatment, with cyclopeptides having advantages of low toxicity and low immunogenicity, offering hope for discovering better compounds for challenging cancer diseases.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Arefeh Dehghani Tafti, Bi Bi Fatemeh Mirjalili, Abdolhamid Bamoniri, Naeimeh Salehi
Summary: In this study, nano-eggshell/Ti(IV) was successfully prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The process showed mild conditions, high yields, and reusability of the catalyst, making it a promising approach for organic synthesis.
Article
Chemistry, Multidisciplinary
Bi Bi Fatemeh Mirjalili, Naeimeh Jalili Bahabadi, Abdolhamid Bamoniri
Summary: A novel deep eutectic solvent containing triethanolamine and sodium acetate was studied and applied as an efficient catalyst for the synthesis of tetrahydrodipyrazolopyridines. The method offers advantages such as easy catalyst preparation, low consumption, short reaction time, high yields, and safe operation.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Mohammad Ali Karimi Zarchi, Kazem Behboodi, Bibi Fatemeh Mirjalili
Summary: The cross-linked poly (4-vinylpyridine) supported TiCl4, [P-4-VP]-Ti(IV), prepared and characterized with various techniques, was utilized as a new polymeric catalyst for the synthesis of imidazole derivatives through a one-pot three-component condensation reaction. This protocol offers advantages such as short reaction time, simple reaction work-up, and reusability of the catalyst.
RESEARCH ON CHEMICAL INTERMEDIATES
(2021)
Article
Chemistry, Multidisciplinary
Maryam Mehravar, Bi Bi Fatemeh Mirjalili, Elaheh Babaei, Abdolhamid Bamoniri
Summary: The nano-SiO2/1,5-diazabicyclo[4.3.0]non-5-en was synthesized and used as a heterogeneous nanocatalyst for the synthesis of tetrahydrobenzo[b]pyran derivatives. The results showed that tetrahydrobenzo[b]pyrans were synthesized in good to high yields and short reaction times, highlighting the efficiency and effectiveness of this method. Overall, the method offers advantages such as short reaction time, simplicity, catalyst recyclability, and high product yields.
Article
Chemistry, Multidisciplinary
Bi Bi Fatemeh Mirjalili, Abdolhamid Bamoniri, Seyede Azita Fazeli-Attar
Summary: A modified bio-based nano-catalyst called Nano-BFn/cellulose was successfully synthesized from nanocellulose and boron triflouride. This catalyst showed several advantages in the synthesis of 7-hydroxycoumarins, including good reaction time, high yield, easy work-up method, reusability, and environmental friendliness.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Chemistry, Multidisciplinary
Dina Mallah, BiBi Fatemeh Mirjalili
Summary: A double-layer magnetic nano-catalyst FNAOSiPPEA/Zn(II) with Lewis acid/Bronsted base structure was prepared, showing good catalytic performance in the synthesis of naphtho[1,2-e][1,3]oxazine derivatives. The catalyst can be reused multiple times with slight loss of activity, indicating its potential for practical applications.
Article
Chemistry, Inorganic & Nuclear
Maryam Mehravar, Bi Bi Fatameh Mirjalili, Elaheh Babaei, Abdolhamid Bamoniri
Summary: A new green protocol utilizing nano-AlPO4/Ti(IV) as a catalyst has been developed for the synthesis of tetrahydrobenzo[a]xanthen-11-ones under solvent-free conditions at 90 degrees C. The protocol offers advantages such as short reaction times, high yields, and easy work-up. Characterization of the catalyst and products was carried out using various analytical techniques.
INORGANIC AND NANO-METAL CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Bi Bi Fatemeh Mirjalili, Roya Soltani, Abdolhannd Bamoniri
Summary: An efficient natural based magnetic nano-catalyst, Nano-kaolin/Ti(IV)/Fe3O4, was synthesized and characterized for the synthesis of biologically active coumarins. The method offers advantages such as easy workup, short reaction times, high product yields, and reusability of the catalyst.
JOURNAL OF NANOSTRUCTURES
(2021)
Article
Chemistry, Inorganic & Nuclear
Leila Amiri-Zirtol, Mohammad Ali Amrollahi, Bibi-Fatemeh Mirjalili
Summary: A new and efficient magnetic composite based on graphene oxide was synthesized, showing high catalytic activity and reusability. The material exhibited strong performance in synthesizing two compounds.
INORGANIC AND NANO-METAL CHEMISTRY
(2021)
