Article
Food Science & Technology
Ningning Xu, Yingping Xiao, Qinggang Xie, Yang Li, Junan Ye, Daxi Ren
Summary: In this study, the occurrence of aflatoxin B1 (AFB1) in total mixed rations (TMR) and aflatoxin M1 (AFM1) in raw and commercial milk in northern China during winter season was investigated. Results showed that all samples from northern China were below the legal limit for AFB1 and AFM1 in raw and commercial milk, with only about 30% of samples exceeding the EU legal limit. However, the northwest area of China had higher AFM1 levels and variance in milk samples, indicating a need for more attention to aflatoxin contamination in this region.
Article
Chemistry, Applied
Ivan Romero-sanchez, Lorena Ramirez-Garcia, Emma Gracia-Lor, Yolanda Madrid-Albarran
Summary: This study evaluated different methods for the extraction and clean-up of aflatoxins from rice, and successfully applied the method to analyze rice samples from Spanish supermarkets. The results showed that the method of methanol-water extraction combined with immunoaffinity column clean-up had favorable performance, with high recoveries and low detection and quantification limits.
Article
Agriculture, Dairy & Animal Science
Rafael Mora-Medina, Antonio Jesus Lora-Benitez, Ana Maria Molina-Lopez, Nahum Ayala-Soldado, Rosario Moyano-Salvago
Summary: In recent years, there has been a growing concern about milk pollution by aflatoxin M1 due to the increasing prevalence of aflatoxins in animal feeding and dairy product consumption. A study was conducted to determine the transfer of aflatoxin B1 into milk and its effects on production and serological parameters in goats. Goats were exposed to different doses of aflatoxin B1 for 31 days and the concentration of aflatoxin M1 in milk was found to significantly increase with the amount of aflatoxin B1 ingested. However, the ingested amount did not affect the aflatoxin M1 carryover, indicating a certain resistance of goats to the effects of aflatoxin B1.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Food Science & Technology
Justin B. Renaud, Jacob P. Walsh, Mark W. Sumarah
Summary: This study reports a simplified synthetic route for the production of unlabelled and labelled aflatoxin B-1-lysine, as well as aflatoxin G(1)-lysine for the first time. The stability of these compounds during storage is also reported.
Review
Agriculture, Dairy & Animal Science
Li Min, Johanna Fink-Gremmels, Dagang Li, Xiong Tong, Jing Tang, Xuemei Nan, Zhongtang Yu, Weidong Chen, Gang Wang
Summary: Milk is considered a perfect natural food for humans and animals, but toxins in the milk from dairy cows may pose risks to human health. Further research is needed to understand the metabolism of toxins in dairy cow feed and their effects on milk.
Article
Food Science & Technology
Bolei Yang, Li Li, Hairong Geng, Gang Wang, Chenxi Zhang, Shuo Yang, Yueju Zhao, Fuguo Xing, Yang Liu
Summary: This study evaluated the detoxification efficacy of sulfurous acid on aflatoxin B1, identified the transformation product AFB1-HSO3, and analyzed its cytotoxicity. High temperature and high concentration of sulfurous acid could significantly degrade AFB1, and the toxicity of the transformation product AFB1-HSO3 was found to be lower than AFB1.
Article
Food Science & Technology
Yanan Gao, Xiaoyu Bao, Lu Meng, Huimin Liu, Jiaqi Wang, Nan Zheng
Summary: This study found that exposure to both AFB1 and AFM1 has a significant impact on intestinal integrity, affecting serum biochemical parameters, villus height/crypt depth ratio, and distribution of tight junction proteins in mice. In vitro experiments showed that AFB1 and AFM1 individually and in combination can decrease cell viability and increase paracellular permeability in a dose-dependent manner. Additionally, AFM1 exacerbated the compromised intestinal barrier induced by AFB1, with evidence suggesting that clathrin-mediated endocytosis may play a role in this process. The study also identified synergistic and additive effects between AFB1 and AFM1, indicating a potential negative impact on human health.
Article
Chemistry, Applied
Jian Sun, Xueping Ning, Lanyu Cui, Wenhui Qin, Wenxu Wang, Shengbin He
Summary: In this study, a reproductive switch DNA template was developed for the precise quantification of aflatoxins. The method demonstrated high sensitivity, good anti-interference abilities, and specificity towards aflatoxin B1. It was successfully applied for the quantification of aflatoxin B1 in complex food samples.
Article
Food Science & Technology
Haocheng Liu, Yuqian Tang, Weili Si, Jiaru Yin, Yujuan Xu, Jiguo Yang
Summary: In this study, a co culture method was used to screen and identify the strain Rhodococcus turbidus PD630 as a highly effective degrader of aflatoxin B1 (AFB1). The extracellular enzyme of PD630 showed the highest degradation activity for AFB1 and maintained high activity over a wide range of pH and temperature. PD630 also demonstrated a high degradation rate for the co-contaminant zearalenone.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Kai Peng, Bing Chen, Hongxia Zhao, Wen Huang
Summary: This study found that dietary AFB(1) up to 1.0 mg/kg was toxic to Lateolabrax maculatus, resulting in reduced growth, enhanced antioxidant and immune response, decreased intestinal trypsin activity, and impaired intestinal morphology.
Article
Agriculture, Multidisciplinary
Lin Ye, Huodai Chen, Karl Wah Keung Tsim, Xing Shen, Xiangmei Li, Xueling Li, Hongtao Lei, Yunle Liu
Summary: Through mouse experiments, it was found that the gut microbiota plays a crucial role in AFB(1)-induced liver injury, as alterations in gut microbiota lead to colonic barrier dysfunction and liver pyroptosis, resulting in hepatic inflammation.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Yan-Zhe Zhang, Qian-Han Zhao, Hong-Wei Duan, Yuan-Jing Zou, Shao-Chen Sun, Lin-Lin Hu
Summary: Our study found that exposure to AFB1 had toxic effects on the distribution of mouse oocyte organelles, leading to a decline in oocyte quality.
Article
Environmental Sciences
Lin-Lin Hu, Shun Chen, Meng-Ying Shen, Qiu-Yan Huang, Hong-Ge Li, Shao-Chen Sun, Jun-Li Wang, Xiao-Qiong Luo
Summary: Aflatoxin, the most common mycotoxin in contaminated crops, has adverse effects on livestock and human health. This study revealed that aflatoxin B1 exposure disrupts the intracellular membrane system, including endoplasmic reticulum, Golgi apparatus, lysosome, and mitochondria, resulting in compromised porcine oocyte maturation quality.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Food Science & Technology
Xue Yang, Xue Li, Yanan Gao, Jiaqi Wang, Nan Zheng
Summary: Aflatoxin B1 (AFB1) and aflatoxin M1 (AFM1) are environmental pollutants that pose a carcinogenic risk to humans. This study found that AFB1 and AFM1 affect intestinal resistance to pollutants and cause lipid metabolism disorders, which may be the main mechanism of their enterotoxicity.
Article
Environmental Sciences
Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Muhammad Kashif Saleemi, Zahoor Ul Hassan
Summary: The study evaluated activated charcoal for its ability to reduce immune suppression caused by Aflatoxin B1 in broiler chickens. The results showed that the dietary addition of activated charcoal could alleviate the toxic effects of AFB1 on immune responses and histological lesions at lower contamination levels, but was less effective at higher levels of dietary AFB1.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
