Article
Infectious Diseases
Elisabeth B. Fjelltveit, Rebecca Jane Cox, Bard Reiakvam Kittang, Bjorn Blomberg, Eirik A. Buanes, Nina Langeland, Kristin G- Mohn
Summary: COVID-19 patients received antibiotics less frequently than influenza patients, both locally and nationally, and there was a reduction in antibiotic prescription rates during the second pandemic wave. This could be attributed to increased clinical experience and evidence debunking the efficacy of antibiotics in treating COVID-19 pneumonia.
INFECTIOUS DISEASES
(2022)
Review
Infectious Diseases
Miguel Servia-Dopazo, Margarita Taracido-Trunk, Adolfo Figueiras
Summary: The prescription of antibiotics by veterinarians is influenced by factors such as fear, self-confidence, business factors, complacency, lack of owner awareness, and demand for antibiotics. Non-clinical factors appear to be modifiable and may be useful for interventions aimed at improving antibiotic use in animals to reduce the global spread of multi-resistant strains.
Article
Oncology
Anupong Sirirungreung, Pei-Chen Lee, Ya-Hui Hu, Zeyan Liew, Beate Ritz, Julia E. Heck
Summary: Maternal infections and antibiotic prescriptions during pregnancy are associated with an increased risk of childhood cancer, especially acute lymphoblastic leukemia (ALL). Maternal use of certain antibiotics, particularly tetracyclines, is also associated with an elevated risk of childhood cancer. Further research is needed in this area.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Immunology
Melissa Depypere, Jonathan Sliepen, Jolien Onsea, Yves Debaveye, Geertje A. M. Govaert, Frank F. A. IJpma, Werner Zimmerli, Willem-Jan Metsemakers
Summary: The purpose of this study was to evaluate the microbiological epidemiology of fracture-related infections (FRI) and analyze the relationship between the time of infection onset and the microbiological etiology. The study found that Staphylococcus aureus was the most frequently isolated pathogen and polymicrobial infections were less common than monomicrobial infections. Early-onset infections were more likely to cause pus or purulent discharge and fistulas.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Pardis Keikhosravani, Fatemeh Jahanmard, Tim Bollen, Kamran Nazmi, Edwin J. A. Veldhuizen, Prasad Gonugunta, Prasaanth Ravi Anusuyadevi, Bart C. H. van der Wal, Charles Vogely, Floris J. Bikker, Peyman Taheri, Harrie Weinans, Saber Amin Yavari
Summary: An antibacterial coating is developed by layer-by-layer assembly of polymers PDLG and GelMA with the loaded peptide CATH-2. The coating exhibits strong antibacterial activity and biocompatibility, making it suitable for preventing infections associated with implants.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Infectious Diseases
Jihyu Oh, So Yeon Park, Jin Seo Lee, Seo Hu Lee
Summary: This study investigated the changes in antibiotic consumption and antimicrobial resistance rates after restricting piperacillin/tazobactam. The results showed a significant decrease in the consumption of piperacillin/tazobactam after implementing the restriction policy. Additionally, the resistance rates of Acinetobacter spp. and other bacteria decreased significantly, indicating a positive impact of piperacillin/tazobactam restriction on controlling bacterial resistance.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Shang-Kai Hung, Chin-Chieh Wu, Avichandra Singh, Jin -Hua Li, Christian Lee, Eric H. Chou, Andrew Pekosz, Richard Rothman, Kuan-Fu Chen
Summary: The study developed and compared clinical feature-based machine learning algorithms for accurately predicting influenza infection in patients with influenza-like illness in emergency departments. The eXtreme Gradient Boosting model outperformed conventional models with superior performance, showing certain clinical features positively or negatively associated with influenza infection. This study highlights the potential of machine learning in improving early diagnosis and treatment of influenza.
BIOMEDICAL JOURNAL
(2023)
Article
Infectious Diseases
Wantin Sribenjalux, Nattawat Larbsida, Sittichai Khamsai, Benjaphol Panyapornsakul, Phitphiboon Deawtrakulchai, Atibordee Meesing
Summary: The study found that the deployment of an electronic clinical pathway can reduce unnecessary antibiotic prescriptions. The antibiotic prescription rate decreased significantly at 6 weeks post-intervention, and the proportion of rational antibiotic prescriptions increased significantly. Antibiotic prescription rates were lower at the community primary care unit, and higher when the physician was a resident or a family doctor.
Article
Immunology
Min Gu, Kaibiao Chen, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, Xiufan Liu
Summary: This study investigated the genetic and biologic characteristics of two Eurasian avian-like H1N1 swine influenza viruses from pigs in China. One swine isolate showed high similarity to contemporary human Eurasian avian-like H1N1 isolates, had a preference for binding to human-type receptors, and demonstrated vigorous replication in mice without the need for adaptation.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Aung H. Aung, David C. Lye, Lin Cui, Chee K. Ooi, Angela L. P. Chow
Summary: The study found that influenza, rhinoviruses, and coronaviruses are common viral pathogens in the tropics, with influenza having biannual peaks while rhinoviruses and coronaviruses circulate year-round without distinct seasonal patterns. The CDC and WHO ILI case definitions showed moderate-to-high positive likelihood ratios for diagnosing influenza, regardless of the time of year, indicating they can be applied in the tropics effectively.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Shen Xingrong, Feng Rui, Chai Jing, Cheng Jing, Isabel Oliver, Helen Lambert, Debin Wang
Summary: Antibiotics prescription was strongly associated with clinical diagnosis of respiratory tract infections (RTIs), but not with the presence of bacteria in patient samples. Some diagnoses may have been given by clinicians to justify the prescription of antibiotics. Additional measures, such as symptoms, should be used in conjunction with diagnosis to supervise or audit excessive use of antibiotics.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Medicine, General & Internal
T. Vieceli, J. Rello
Summary: Internal Medicine wards, emergency departments, and intensive care units are key areas for antibiotic stewardship, with personalized prescriptions, rapid diagnostic tests, and multidisciplinary approaches being essential for improving the appropriateness and safety of antibiotic use.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Infectious Diseases
Sade Stenlund, Louise C. Masse, David Stenlund, Lauri Sillanmaki, Kirstin C. Appelt, Heli Koivumaa-Honkanen, Paivi Rautava, Sakari Suominen, David M. Patrick
Summary: This study analyzed the relationship between patients' psychosocial characteristics and antibiotic overuse. The results showed that adverse psychosocial characteristics were not directly related to increased antibiotic prescriptions, but were associated with poor general health status, which in turn was associated with more antibiotic prescriptions.
Article
Public, Environmental & Occupational Health
Woohyeon Kim, Euna Han
Summary: Inappropriate antibiotic use is a main driver of antibiotic resistance. This study examined the contribution of patient, provider, and other factors to antibiotic prescriptions for acute upper respiratory tract infection. Analyzing data from the Korean National Health Insurance Sample Cohort Database, the results showed that both patient and provider factors influence antibiotic use, with providers having a stronger impact. The findings highlight the importance of regulations targeting both patients and providers in reducing antibiotic consumption.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Immunology
Koen J. van Aerde, Liza de Haan, Mattijn van Leur, Gerardus P. Gerrits, Henk Schers, Henriette A. Moll, Nienke N. Hagedoorn, Jethro A. Herberg, Michael Levin, Irene Rivero-Calle, Marien de Jonge, Ronald de Groot, Michiel van der Flier
Summary: The study examined the management of febrile children with respiratory tract infections at three different levels of healthcare in the Netherlands, finding comparable antibiotic prescription rates but relatively high overall rates inconsistent with national guidelines. Improvement in antibiotic stewardship is needed across all levels of healthcare, particularly in implementing guidelines for prescribing narrow-spectrum antibiotics in hospital settings.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
