Article
Dermatology
Yingzhi Qian, Paul Johannet, Amelia Sawyers, Jaehong Yu, Iman Osman, Judy Zhong
Summary: The study found that racial disparities among cutaneous melanoma patients have worsened from before the year 2000 to 2010 or later. Patients with localized disease across all minority groups suffered increasing disparity, highlighting the need for improved postdiagnosis management for minorities to mitigate disparity and improve survival.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Hematology
Lin Quan, Zhen He, Xiaoling Zuo, Lei Cao, Yi Wang, Hongyu Dai, Wei Wu, Xiao Shi, Hailing Liu
Summary: This population-based study assessed the latest survival and treatment strategies for patients with primary mediastinal large B-cell lymphoma (PMBCL). The study found that the survival outcomes for PMBCL patients have significantly improved over time, with chemotherapy being the primary treatment modality and a decline in the utilization of surgery and radiation therapy. However, the value of radiotherapy in PMBCL is still debated and requires further prospective evaluation.
Article
Oncology
Yufan Tang, Ting Yan, Wangwang Qiu, Zheng Ding, Youben Fan, Qiong Jiao, Zhili Yang
Summary: The study aims to explore the optimal treatment for stage IE primary thyroid lymphoma (PTL). By comparing the survival outcomes and treatment modalities, the study found that surgery is a viable treatment option.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Hui Qian, Zhihao Yang, Linqiang Cai, Huawei Chen
Summary: This study analyzed the conditional survival of elderly patients with primary central nervous system lymphoma (PCNSL) using data from the SEER program. A nomogram model based on conditional survival was successfully constructed, showing that the survival rate of elderly patients increased over time. The model has favorable prediction performance.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Hematology
G. Tjitske Los-deVries, Wendy B. C. Stevens, Erik van Dijk, Carole Langois-Jacques, Andrew J. Clear, Phylicia Stathi, Margaretha G. M. Roemer, Matias Mendeville, Nathalie J. Hijmering, Birgitta Sander, Andreas Rosenwald, Maria Calaminici, Eva Hoster, Wolfgang Hiddemann, Philippe Gaulard, Gilles Salles, Heike Horn, Wolfram Klapper, Luc Xerri, Catherine Burton, Reuben M. Tooze, Alexandra G. Smith, Christian Buske, David W. Scott, Yasodha Natkunam, Ranjana Advani, Laurie H. Sehn, John Raemaekers, John Gribben, Eva Kimby, Marie Jose Kersten, Delphine Maucort-Boulch, Bauke Ylstra, Daphne de Jong
Summary: The genomic and immune microenvironmental features of follicular lymphoma (FL) differ between stage I and stage III/IV, with distinct differences in cell populations and mutations. This exploratory study provides new insights into the heterogeneity of FL and its underlying oncogenic pathways.
Article
Cardiac & Cardiovascular Systems
Kanhua Yin, Hilliard Brydges, Kyle W. Lawrence, Yaguang Wei, Karl J. Karlson, David B. McAneny, Niloo M. Edwards, Michael J. Reardon, Nikola Dobrilovic
Summary: This study found that surgical resection was not associated with survival in patients with primary cardiac lymphoma. Chemotherapy was the main treatment option and was associated with improved survival. Increasing age and advanced stage were associated with worse outcomes.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Oncology
Junhong Du, Yuemei Cheng, Dan Hu, Yijuan Xing, Ling Yue, Ruifen He, Hongli Li, Chang Liu, Xiaolei Liang, Yongxiu Yang
Summary: The study aimed to establish a nomogram-based prognostic stratification to identify uterine sarcoma patients who might benefit from adjuvant radiotherapy. The results showed that adjuvant radiotherapy had a significant survival benefit for high-risk patients, while it did not improve the survival outcomes of low- and intermediate-risk groups.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Cell Biology
Huijiang Gao, Yuanyong Wang, Zhihui Jiang, Guodong Shi, Shiyu Hu, Jiangshan Ai, Zhaofeng Wang, Yucheng Wei
Summary: This study explores the link between adjuvant radiotherapy and survival in pN0 esophageal cancer patients. It suggests that adjuvant radiotherapy following upfront esophagectomy can improve the overall survival of high-risk patients. This finding has significant implications for the use of adjuvant radiotherapy in pN0 esophageal cancer.
Article
Oncology
Wen Zhao, Qi Tian, Andi Zhao, Biyuan Wang, Jiao Yang, Le Wang, Lingxiao Zhang, Danfeng Dong, Ling Chen, Jin Yang
Summary: Among MPTB patients, adjuvant RT did not improve overall survival or disease-specific survival. A survival benefit trend from adjuvant RT existed in patients with tumor larger than 50 mm and undergoing breast conservation surgery.
Article
Oncology
Aino Rajamaki, Mika Hujo, Reijo Sund, Roosa E. I. Prusila, Milla E. L. Kuusisto, Hanne Kuitunen, Esa Jantunen, Santiago Mercadal, Marc Sorigue, Juan-Manuel Sancho, Kaisa Sunela, Outi Kuittinen
Summary: This study examined the proportion of deaths from progressive lymphoma and the impact of follicular lymphoma (FL) on survival. The results showed that deaths from progressive lymphoma are nearly as common as deaths from other causes in FL patients during the rituximab era. Despite improvements in survival, there was evidence of excess mortality resulting from FL for at least 10 years after diagnosis.
Article
Public, Environmental & Occupational Health
Jiazhao Song, Xiaoli Kang, Yupeng Di, Gang Ren, Yingjie Wang
Summary: The study evaluated the impact of external beam radiotherapy on overall survival of gallbladder cancer patients and found that both adjuvant and palliative radiation treatment were associated with a survival benefit, indicating that patients can derive a survival benefit from external beam radiotherapy.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Hematology
Sarah Haebe, Tanaya Shree, Anuja Sathe, Grady Day, Debra K. Czerwinski, Susan M. Grimes, HoJoon Lee, Michael S. Binkley, Steven R. Long, Brock Martin, Hanlee P. Ji, Ronald Levy
Summary: The study found that B-cell receptor subclones were shared between the two tumor sites in some patients with follicular lymphoma, while in many patients, the disease had evolved separately with limited tumor cell migration between the sites. Differences in tumor gene expression and cell surface protein profiles were observed in patients with divergent BCR evolution. Additionally, a specific correlation was detected between site-to-site tumor heterogeneity and T follicular helper (Tfh) cell abundance.
Article
Medicine, General & Internal
Geovanne Pedro Mauro, Carolina Trindade Mello Medici, Lucas Coelho Casimiro, Eduardo Weltman
Summary: The study evaluated the efficacy of radiotherapy for follicular lymphoma under different management scenarios. Results showed good overall survival and progression-free survival rates for patients treated with radiation, although some patients may experience transformation into aggressive lymphomas, which can be effectively managed with rituximab-based systemic treatment.
Letter
Oncology
John L. Vaughn, Narendranath Epperla
Summary: This population-based study aimed to compare the survival outcomes of patients with transformed follicular lymphoma (t-FL) and de novo diffuse large B-cell lymphoma (DLBCL). The results showed that patients with t-FL had inferior survival rates in the modern era and should be prioritized for enrollment in clinical trials.
BIOMARKER RESEARCH
(2023)
Article
Oncology
Jing Jia, Wenming Chen
Summary: This study evaluated the role of radiation therapy (RT) in primary tonsil diffuse large B cell lymphoma (PT-DLBCL) using the SEER database, finding a favorable survival outcome in early stages rather than advanced stages. A prognostic model was established to identify high-risk patients and improve prognosis.
RADIATION ONCOLOGY
(2021)
