Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers

Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions

(2015) Bin Guan et al.   NEOPLASIA

HyperModules: identifying clinically and phenotypically significant network modules with disease mutations for biomarker discovery

(2014) Alvin Leung et al.   BIOINFORMATICS

Aberrant expression of δ-like ligand 4 contributes significantly to axillary lymph node metastasis and predicts postoperative outcome in breast cancer

(2014) Min Xiao et al.   HUMAN PATHOLOGY

Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins

(2014) HongBin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plakophilin-2 Promotes Tumor Development by Enhancing Ligand-Dependent and -Independent Epidermal Growth Factor Receptor Dimerization and Activation

(2014) K.-i. Arimoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

(2014) Jens G Lohr et al.   NATURE BIOTECHNOLOGY

Genome-wide analysis of noncoding regulatory mutations in cancer

(2014) Nils Weinhold et al.   NATURE GENETICS

Predicting Survival of De Novo Metastatic Breast Cancer in Asian Women: Systematic Review and Validation Study

(2014) Hui Miao et al.   PLoS One

CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression

(2013) Yunshan Wang et al.   CANCER RESEARCH

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Emerging Roles of Claudins in Human Cancer

(2013) Mi Kwon   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical implications of DLL4 expression in gastric cancer

(2013) Sumiya Ishigami et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

(2013) Weiyi Toy et al.   NATURE GENETICS

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Efficient methods for identifying mutated driver pathways in cancer

(2012) Junfei Zhao et al.   BIOINFORMATICS

Immunohistochemical study of pElk-1 expression in human breast cancer: Association with breast cancer biologic profile and clinicopathologic features

(2012) Aggelos Laliotis et al.   BREAST

SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE)

(2012) Chunyu Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice

(2012) Rong Li et al.   CLINICAL & EXPERIMENTAL METASTASIS

Detecting overlapping protein complexes in protein-protein interaction networks

(2012) Tamás Nepusz et al.   NATURE METHODS

Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2011) F. Cardoso et al.   ANNALS OF ONCOLOGY

Inferring causal genomic alterations in breast cancer using gene expression data

(2011) Linh M Tran et al.   BMC Systems Biology

De novo discovery of mutated driver pathways in cancer

(2011) F. Vandin et al.   GENOME RESEARCH

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

(2011) Siân Jones et al.   HUMAN MUTATION

Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.

(2011) Camille Lobry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

(2011) Kai Wang et al.   NATURE GENETICS

Expression of Vascular Notch Ligand Delta-Like 4 and Inflammatory Markers in Breast Cancer

(2010) Adrian M. Jubb et al.   AMERICAN JOURNAL OF PATHOLOGY

Novel protein interactors of urokinase-type plasminogen activator receptor

(2010) Ahmed H. Mekkawy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HAX-1 overexpression, splicing and cellular localization in tumors

(2010) Alicja Trebinska et al.   BMC CANCER

Claudin 1 in Breast Tumorigenesis: Revelation of a Possible Novel “Claudin High” Subset of Breast Cancers

(2010) Yvonne Myal et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

(2010) Rebecca W. Scott et al.   JOURNAL OF CELL BIOLOGY

IKK  controls canonical TGF -SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells

(2010) M. Brandl et al.   JOURNAL OF CELL SCIENCE

PAX5  Enhances the Epithelial Behavior of Human Mammary Carcinoma Cells

(2010) L. J-P Vidal et al.   MOLECULAR CANCER RESEARCH

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

(2010) Siân Jones et al.   SCIENCE

The metastatic cascade is reflected in the transcriptome of metastatic canine mammary carcinomas

(2010) R. Klopfleisch et al.   VETERINARY JOURNAL

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer

(2009) A M Jubb et al.   BRITISH JOURNAL OF CANCER

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

A gene expression signature that defines breast cancer metastases

(2009) Rachel E. Ellsworth et al.   CLINICAL & EXPERIMENTAL METASTASIS

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

The Cdk inhibitor p57Kip2 controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics

(2009) P Vlachos et al.   ONCOGENE

AUTOMATIC MODELING OF SIGNALING PATHWAYS BY NETWORK FLOW MODEL

(2009) XING-MING ZHAO et al.   Journal of Bioinformatics and Computational Biology

Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways

(2008) T. T. Onder et al.   CANCER RESEARCH

Zeb1 links epithelial-mesenchymal transition and cellular senescence

(2008) Y. Liu et al.   DEVELOPMENT

Troglitazone inhibits cell migration, adhesion, and spreading by modulating cytoskeletal rearrangement in human breast cancer cells

(2008) Pei-Shan Wang et al.   MOLECULAR CARCINOGENESIS

Human Proteinpedia enables sharing of human protein data

(2008) Suresh Mathivanan et al.   NATURE BIOTECHNOLOGY

Overexpression of Separase induces aneuploidy and mammary tumorigenesis

(2008) N. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA