Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders

Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders

(2016) Friederike Tuller et al.   Journal of Neuroinflammation

Mapping autoantigen epitopes: molecular insights into autoantibody-associated disorders of the nervous system

(2016) Nese Sinmaz et al.   Journal of Neuroinflammation

A clinical approach to diagnosis of autoimmune encephalitis

(2016) Francesc Graus et al.   LANCET NEUROLOGY

Autoantibodies in movement and psychiatric disorders: updated concepts in detection methods, pathogenicity, and CNS entry

(2015) Nese Sinmaz et al.   Annals of the New York Academy of Sciences

N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane

(2015) Chengchun Min et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Antibodies to Surface Dopamine-2 Receptor and N-Methyl-D-Aspartate Receptor in the First Episode of Acute Psychosis in Children

(2015) Karrnan Pathmanandavel et al.   BIOLOGICAL PSYCHIATRY

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

(2015) Sukhvir Wright et al.   BRAIN

Mutagenesis of the Aquaporin 4 Extracellular Domains Defines Restricted Binding Patterns of Pathogenic Neuromyelitis Optica IgG

(2015) Gregory P. Owens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Infectious and Autoantibody-Associated Encephalitis: Clinical Features and Long-term Outcome

(2015) S. C. Pillai et al.   PEDIATRICS

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Specific ContactinN-Glycans Are Implicated in Neurofascin Binding and Autoimmune Targeting in Peripheral Neuropathies

(2014) Marilyne Labasque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antigenic and mechanistic characterization of anti-AMPA receptor encephalitis

(2014) Amy J. Gleichman et al.   Annals of Clinical and Translational Neurology

Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease

(2013) C. J. Cox et al.   JOURNAL OF IMMUNOLOGY

Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases

(2013) M. C. Mayer et al.   JOURNAL OF IMMUNOLOGY

Herpes simplex encephalitis relapse with chorea is associated with autoantibodies toN-Methyl-D-aspartate receptor or dopamine-2 receptor

(2013) Shekeeb S. Mohammad et al.   MOVEMENT DISORDERS

A Cleavable N-Terminal Signal Peptide Promotes Widespread Olfactory Receptor Surface Expression in HEK293T Cells

(2013) Blythe D. Shepard et al.   PLoS One

High-throughput Flow Cytometry Cell-based Assay to Detect Antibodies to N-Methyl-D-aspartate Receptor or Dopamine-2 Receptor in Human Serum

(2013) Mazen Amatoury et al.   Jove-Journal of Visualized Experiments

Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognizeClostridiumABC transporter

(2012) Michel Varrin-Doyer et al.   ANNALS OF NEUROLOGY

Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders

(2012) Russell C. Dale et al.   BRAIN

Autoantigen-Specific B-Cell Depletion Overcomes Failed Immune Tolerance in Type 1 Diabetes

(2012) R. A. Henry et al.   DIABETES

Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays

(2012) Raffaele Iorio et al.   JOURNAL OF AUTOIMMUNITY

Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain

(2012) A. J. Gleichman et al.   JOURNAL OF NEUROSCIENCE

Behavioral, Pharmacological and Immunological Abnormalities after Streptococcal Exposure: A Novel Rat Model of Sydenham Chorea and Related Neuropsychiatric Disorders

(2012) Lior Brimberg et al.   NEUROPSYCHOPHARMACOLOGY

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

The N-terminal region of the dopamine D2 receptor, a rhodopsin-like GPCR, regulates correct integration into the plasma membrane and endocytic routes

(2011) DI Cho et al.   BRITISH JOURNAL OF PHARMACOLOGY

Novel Dopamine D2 Receptor Signaling through Proteins Interacting with the Third Cytoplasmic Loop

(2011) Kohji Fukunaga et al.   MOLECULAR NEUROBIOLOGY

Antibody binding to neuronal surface in Sydenham chorea, but not in PANDAS or Tourette syndrome

(2011) F. Brilot et al.   NEUROLOGY

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity

(2011) O. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moving towards a cure: blocking pathogenic antibodies in systemic lupus erythematosus

(2010) B. Diamond et al.   JOURNAL OF INTERNAL MEDICINE

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease

(2009) Fabienne Brilot et al.   ANNALS OF NEUROLOGY

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

(2009) Meizan Lai et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Mammalian Type I Gonadotropin-Releasing Hormone Receptors Undergo Slow, Constitutive, Agonist-Independent Internalization

(2007) Adam J. Pawson et al.   ENDOCRINOLOGY