Review
Immunology
Zhuanzhuan Liu, Qingxin Zhang, Liya Li, Junjie He, Jinyang Guo, Zichen Wang, Yige Huang, Zimeng Xi, Fei Yuan, Yiji Li, Tingting Li
Summary: This review explores the correlations between temperature and dengue epidemics, including the distribution and development of Aedes mosquitoes, the structure of DENV, and the vector competence of Aedes mosquitoes. Additionally, it discusses the immune and metabolic mechanism through which temperature affects the vector competence of Aedes mosquitoes to transmit DENV.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Environmental Sciences
Syed Shah Areeb Hussain, Ramesh C. Dhiman
Summary: This study used species distribution modeling to predict the current and future distribution of Aedes aegypti and Aedes albopictus vectors in India. The results indicate that Aedes aegypti is prevalent in most parts of southern India, the eastern coastline, northeastern states, and the northern plains, while Aedes albopictus has localized distribution in the eastern and western coastlines, northeastern states, and lower Himalayas. Future scenarios of climate change may lead to the expansion of Aedes aegypti in unsuitable regions and Aedes albopictus in the upper and trans Himalaya regions.
Article
Engineering, Multidisciplinary
Mohsin Khan, Michael Pedersen, Min Zhu, Hong Zhang, Lai Zhang
Summary: This paper extends a compartmental model to analyze the impact of climate and population changes on the spread of dengue fever. The study predicts a significant expansion of the risk area for dengue fever in mainland China and identifies temperature, precipitation, and population density as key factors influencing the spread patterns.
APPLIED MATHEMATICAL MODELLING
(2023)
Article
Medicine, General & Internal
Triwibowo Ambar Garjito, Lulus Susanti, Mujiyono Mujiyono, Mega Tyas Prihatin, Dwi Susilo, Sidiq Setyo Nugroho, Mujiyanto Mujiyanto, Raden Ajeng Wigati, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: There are various methods to collect and assess the abundance of dengue vector mosquitoes, but the lack of long-term sampling methods may result in variability and lack of statistical significance in the results. There is no correlation between the collection methods and the presence of dengue virus in mosquitoes or the incidence of dengue, and the efficacy of a given method is inconsistent across different locations.
FRONTIERS IN MEDICINE
(2021)
Article
Environmental Sciences
Cory W. Morin, Samuel Sellers, Kristie L. Ebi
Summary: This study explored the relationship between seasonal climate variability and dengue fever (DF) in Brazil using temperature-based models. The results showed that areas with higher mosquito survival probabilities and shorter extrinsic incubation periods (EIPs) were more likely to have DF case reports, but with significant intra-annual variability. The study also extrapolated the findings to the Americas, mapping the seasonal change in the range of areas suitable for dengue virus transmission and the population living in those areas using climate data from the past decade (2010-2019).
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Parasitology
Maria C. Carrasquilla, Mario I. Ortiz, Cielo Leon, Silvia Rondon, Manisha A. Kulkarni, Benoit Talbot, Beate Sander, Heriberto Vasquez, Juan M. Cordovez, Camila Gonzalez
Summary: A study conducted in Ibague, Colombia found that Aedes aegypti and Aedes albopictus mosquitoes are vectors for dengue, Zika, and chikungunya viruses, with dengue and chikungunya circulating in the area but Zika virus remaining undetected. The research results showed that mosquitoes were mainly found in low socioeconomic areas and indoors, with a higher number of female mosquitoes that have fed on human blood, indicating a high risk of arbovirus transmission in Ibague.
PARASITES & VECTORS
(2021)
Article
Parasitology
Lie Cheng, Wei-Liang Liu, Matthew P. Su, Shu-Chen Huang, Jen-Ren Wang, Chun-Hong Chen
Summary: In this study, we found that prohemocytes were the major type of hemocyte infected by DENV in both Ae. aegypti and Ae. albopictus. The infection rate of prohemocytes in Ae. albopictus was lower than that in Ae. aegypti, which may explain why systemic DENV infection in Ae. albopictus is less efficient than in Ae. aegypti and why Ae. albopictus is less correlated to dengue fever outbreaks.
PARASITES & VECTORS
(2022)
Article
Microbiology
Abdullah A. Alomar, Bradley H. Eastmond, Zoi Rapti, Edward D. Walker, Barry W. Alto
Summary: This study evaluated the impact of consuming toxic sugar bait on the vectorial capacity of Aedes albopictus mosquitoes for dengue virus. It found that while ingestion of the bait increased the mosquito's susceptibility to virus infection and transmission, it also reduced their survival rate, ultimately resulting in a lower predicted vectorial capacity.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Medicine, General & Internal
Felipe J. Colon-Gonzalez, Leonardo Soares Bastos, Barbar Hofmann, Alison Hopkin, Quillon Harpham, Tom Crocker, Rosanna Amato, Iacopo Ferrario, Francesca Moschini, Samuel James, Sajni Malde, Eleanor Ainscoe, Vu Sinh Nam, Dang Quang Tan, Nguyen Duc Khoa, Mark Harrison, Gina Tsarouchi, Darren Lumbroso, Oliver J. Brady, Rachel Lowe
Summary: The study introduces an operational seasonal dengue forecasting system for Vietnam that combines Earth observations, seasonal climate forecasts, and lagged dengue cases to predict dengue risk up to 6 months ahead. The superensemble of probabilistic models generated more accurate predictions of dengue incidence compared to individual models across different time horizons and transmission settings. The system demonstrated added value by making slightly more accurate predictions and having better outbreak detection capability than baseline models.
Article
Infectious Diseases
Nichar Gregory, Robert M. Ewers, Arthur Y. C. Chung, Lauren J. Cator
Summary: Changes in land-use and associated shifts in environmental conditions can affect the transmission and emergence of mosquito-borne diseases due to the sensitivity of mosquito traits to temperature. Predicting disease transmission is crucial for disease control and identifying hotspots.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Immunology
Triwibowo Ambar Garjito, Widiarti Widiarti, Muhammad Choirul Hidajat, Sri Wahyuni Handayani, Mujiyono Mujiyono, Mega Tyas Prihatin, Rosichon Ubaidillah, Mohammad Sudomo, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: Genetic diversity differs between Ae. aegypti and Aedes albopictus populations in Indonesia, with a high degree of homogeneity observed across regions, potentially indicating population replacement.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Parasitology
Rasika Dalpadado, Deepika Amarasinghe, Nayana Gunathilaka, Nalin Ariyarathna
Summary: This study investigated the bionomics aspects of Aedes aegypti and Aedes albopictus in Sri Lanka, including breeding, resting, host-seeking, and feeding preferences. The results showed that Aedes aegypti predominantly breeds in temporary removals and discarded non-degradables, while Aedes albopictus mainly oviposits in natural locations and temporary removals. Adult mosquitoes of both species tend to rest indoors, with Aedes albopictus being more prevalent in outdoor vegetation. The biting patterns of these mosquitoes exhibit a typical diurnal rhythm, with two peaks of activity in the morning and afternoon.
PARASITES & VECTORS
(2022)
Article
Entomology
Jameel M. Abduljalil, Fahd M. Abd Al Galil
Summary: Deciphering the molecular interactions between DENV and its vector is a promising field to develop efficient control strategies for DENV.
JOURNAL OF INSECT PHYSIOLOGY
(2022)
Article
Infectious Diseases
Lauren A. Castro, Nicholas Generous, Wei Luo, Ana Pastore y Piontti, Kaitlyn Martinez, Marcelo F. C. Gomes, Dave Osthus, Geoffrey Fairchild, Amanda Ziemann, Alessandro Vespignani, Mauricio Santillana, Carrie A. Manore, Sara Y. Del Valle
Summary: Dengue virus poses a significant public health challenge in Brazil, with seasonal dynamics hindering preparation efforts. A framework was presented to characterize weekly dengue activity in Brazil from 2010-2016, with climate factors playing a key role in seasonal outbreaks. Remote sensing and movement patterns were found to be useful proxies for predicting outbreak properties.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Infectious Diseases
Yan Liu, Xia Wang, Sanyi Tang, Robert A. Cheke
Summary: This study built a mathematical model based on meteorological and mosquito vector monitoring data in Guangdong Province, China, to explore the effects of temperature and rainfall on the population dynamics of Aedes albopictus. The study found that temperature and rainfall had different effects on the developmental stages of mosquitoes in different periods and locations. It also identified rainfall as being more important than temperature distribution and evenness for mosquito population development, with peak summer rainfall being the best indicator.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Francesco Marabita, Tojo James, Anu Karhu, Heidi Virtanen, Kaisa Kettunen, Hans Stenlund, Fredrik Boulund, Cecilia Hellstrom, Maja Neiman, Robert Mills, Teemu Perheentupa, Hannele Laivuori, Pyry Helkkula, Myles Byrne, Ilkka Jokinen, Harri Honko, Antti Kallonen, Miikka Ermes, Heidi Simila, Mikko Lindholm, Elisabeth Widen, Samuli Ripatti, Maritta Perala-Heape, Lars Engstrand, Peter Nilsson, Thomas Moritz, Timo Miettinen, Riitta Sallinen, Olli Kallioniemi
Summary: This study explored personalized and predictive health care by collecting various biological data. The results demonstrated distinct molecular factors associated with obesity, diabetes, liver function, cardiovascular disease, etc.
Article
Public, Environmental & Occupational Health
Ake Brannstrom, Henrik Sjoedin, Joacim Rockloev
Summary: This article presents a method for estimating the true number of cases in an epidemic and applies it to COVID-19. The study found that the number of unreported COVID-19 infections in March 2020 was likely to be at least ten times higher than the reported cases, with the United Kingdom showing particularly high underestimation.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Maeve Long, Alvaro Sanchez-Martinez, Marianna Longo, Fumi Suomi, Hans Stenlund, Annika Johansson, Homa Ehsan, Veijo T. Salo, Lambert Montava-Garriga, Seyedehshima Naddafi, Elina Ikonen, Ian G. Ganley, Alexander J. Whitworth, Thomas G. McWilliams
Summary: Mitophagy removes defective mitochondria through lysosomal elimination. Iron depletion triggers lipid metabolism remodeling and lipid droplets bordering mitochondria. Inhibiting DGAT1 restricts mitophagy and leads to cell death.
Letter
Public, Environmental & Occupational Health
Ying Liu, Joacim Rockloev
JOURNAL OF TRAVEL MEDICINE
(2022)
Review
Infectious Diseases
Jan C. Semenza, Joacim Rocklov, Kristie L. Ebi
Summary: Climate change adversely affects the burden of infectious diseases worldwide, particularly vector-borne diseases and other climate-sensitive diseases. The changing climate can alter disease distribution and transmission, increasing the risk of outbreaks.
INFECTIOUS DISEASES AND THERAPY
(2022)
Article
Parasitology
Prasad Liyanage, Yesim Tozan, Hasitha Aravinda Tissera, Hans J. Overgaard, Joacim Rocklov
Summary: Dengue is a major public health problem in Sri Lanka, and the association between Aedes larval indices and dengue incidence is poorly understood. This study analyzed the data of Aedes larval indices and dengue cases in Kalutara district, and found that all three larval indices were associated with dengue risk and identified threshold values. The study demonstrated the potential of vector surveillance information in developing a warning system for control strategies.
PARASITES & VECTORS
(2022)
Article
Plant Sciences
Daniela Liebsch, Marta Juvany, Zhonghai Li, Hou-Ling Wang, Agnieszka Ziolkowska, Daria Chrobok, Clement Boussardon, Xing Wen, Simon R. Law, Helena Janeckova, Bastiaan Brouwer, Pernilla Linden, Nicolas Delhomme, Hans Stenlund, Thomas Moritz, Per Gardestrom, Hongwei Guo, Olivier Keech
Summary: Arginine and ornithine can affect the progression of leaf senescence and delay the aging process. They can delay leaf senescence by fueling the Krebs cycle or the production of polyamines. The conversion of putrescine to spermidine is controlled in an age-dependent manner and spermidine represses senescence by interfering with ethylene signaling.
Article
Plant Sciences
Laura J. A. van Dijk, Emilia D. E. Regazzoni, Benedicte R. Albrectsen, Johan Ehrlen, Ahmed Abdelfattah, Hans Stenlund, Katharina Pawlowski, Ayco J. M. Tack
Summary: In this study, the metabolic response of pedunculate oak to different soil microbiomes and aboveground single and dual attack was assessed using GC-MS. The results showed that distinct soil microbiomes were not associated with differences in the metabolic profile of oak seedling leaves. Single attacks by aphids or mildew had pronounced but different effects on the oak leaf metabolome. However, no difference was detected between the metabolomes of healthy seedlings and seedlings attacked by both aphids and powdery mildew. This study highlights the importance of considering the impacts of multiple attackers to gain mechanistic insights into the ecology and evolution of species interactions and the structure of plant-associated communities, as well as for the development of sustainable strategies to control agricultural pests and diseases and plant breeding.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Medicine, General & Internal
Marina Romanello, Claudia Di Napoli, Paul Drummond, Carole Green, Harry Kennard, Pete Lampard, Daniel Scamman, Nigel Arnell, Sonja Ayeb-Karlsson, Lea Berrang Ford, Kristine Belesova, Kathryn Bowen, Wenjia Cai, Max Callaghan, Diarmid Campbell-Lendrum, Jonathan Chambers, Kim R. van Daalen, Carole Dalin, Niheer Dasandi, Shouro Dasgupta, Michael Davies, Paula Dominguez-Salas, Robert Dubrow, Kristie L. Ebi, Matthew Eckelman, Paul Ekins, Luis E. Escobar, Lucien Georgeson, Hilary Graham, Samuel H. Gunther, Ian Hamilton, Yun Hang, Risto Hanninen, Stella Hartinger, Kehan He, Jeremy J. Hess, Shih-Che Hsu, Slava Jankin, Louis Jamart, Ollie Jay, Ilan Kelman, Gregor Kiesewetter, Patrick Kinney, Tord Kjellstrom, Dominic Kniveton, Jason K. W. Lee, Bruno Lemke, Yang Liu, Zhao Liu, Melissa Lott, Martin Lotto Batista, Rachel Lowe, Frances MacGuire, Maquins Odhiambo Sewe, Jaime Martinez-Urtaza, Mark Maslin, Lucy McAllister, Alice McGushin, Celia McMichael, Zhifu Mi, James Milner, Kelton Minor, Jan C. Minx, Nahid Mohajeri, Maziar Moradi-Lakeh, Karyn Morrissey, Simon Munzert, Kris A. Murray, Tara Neville, Maria Nilsson, Nick Obradovich, Megan B. O'Hare, Tadj Oreszczyn, Matthias Otto, Fereidoon Owfi, Olivia Pearman, Mahnaz Rabbaniha, Elizabeth J. Z. Robinson, Joacim Rocklov, Renee N. Salas, Jan C. Semenza, Jodi D. Sherman, Liuhua Shi, Joy Shumake-Guillemot, Grant Silbert, Mikhail Sofiev, Marco Springmann, Jennifer Stowell, Meisam Tabatabaei, Jonathon Taylor, Joaquin Trinanes, Fabian Wagner, Paul Wilkinson, Matthew Winning, Marisol Yglesias-Gonzalez, Shihui Zhang, Peng Gong, Hugh Montgomery, Anthony Costello
Article
Multidisciplinary Sciences
V. V. L. Albani, R. A. S. Albani, E. Massad, J. P. Zubelli
Summary: This study introduces a parsimonious and effective susceptible-exposed-infected-removed-type model that takes into account the temporal changes in transmission and death rates. The model is calibrated using official reports from different regions and various methods are proposed to extend the transmission parameter for forecasting. The accuracy of the forecasts is evaluated using real data, and one of the models successfully predicts the magnitude of multiple infection waves, including the one caused by the Omicron variant.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Kim R. van Daalen, Marina Romanello, Joacim Rockloev, Jan C. Semenza, Cathryn Tonne, Anil Markandya, Niheer Dasandi, Slava Jankin, Hicham Achebak, Joan Ballester, Hannah Bechara, Max W. Callaghan, Jonathan Chambers, Shouro Dasgupta, Paul Drummond, Zia Farooq, Olga Gasparyan, Nube Gonzalez-Reviriego, Ian Hamilton, Risto Hanninen, Aleksandra Kazmierczak, Vladimir Kendrovski, Harry Kennard, Gregor Kiesewetter, Simon J. Lloyd, Martin Lotto Batista, Jaime Martinez-Urtaza, Carles Mila, Jan C. Minx, Mark Nieuwenhuijsen, Julia Palamarchuk, Marcos Quijal-Zamorano, Elizabeth J. Z. Robinson, Daniel Scamman, Oliver Schmoll, Maquins Odhiambo Sewe, Henrik Sjodin, Mikhail Sofiev, Balakrishnan Solaraju-Murali, Marco Springmann, Joaquin Trinanes, Josep M. Anto, Maria Nilsson, Rachel Lowe
Summary: In the past few decades, Europe has made significant progress in public health, but is facing challenges such as the COVID-19 pandemic, the Russian invasion of Ukraine, the migrant crisis, environmental degradation, and inequality. As a major economy, Europe has the responsibility and opportunity to lead the transition to a low-carbon economy and a healthier society. The Lancet Countdown in Europe aims to monitor the links between health and climate change in Europe and support measures to protect human health.
LANCET PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Lokeshwaran Manoharan, Bodil Roth, Corinna Bang, Hans Stenlund, Bodil Ohlsson
Summary: The adoption of an Okinawan-based Nordic diet (O-BN) can improve weight, glucose, and lipid metabolism in individuals with type 2 diabetes. This study found changes in metabolomics and gut microbiota during O-BN and correlated these changes with clinical outcomes.
Article
Health Care Sciences & Services
Joacim Rockloev, Jan C. Semenza, Shouro Dasgupta, ElizabethJ. Z. Robinson, Ahmed Abd El Wahed, Tilly Alcayna, Cristina Arnes-Sanz, Meghan Bailey, Till Baernighausen, Frederic Bartumeus, Carme Borrell, Laurens M. Bouwer, Pierre-Antoine Bretonniere, Aditi Bunker, Chloe Chavardes, Kim R. van Daalen, Joao Encarnacao, Nube Gonzalez-Reviriego, Junwen Guo, Katie Johnson, Marion P. G. Koopmans, Maria Manez Costa, Antonios Michaelakis, Tomas Montalvo, Anna Omazic, John R. B. Palmer, Raman Preet, Marina Romanello, Mohammad Shafiul Alam, Reina S. Sikkema, Marta Terrado, Marina Treskova, Rachel Lowe
Summary: Climate change is a driver of infectious disease outbreaks and expansions in Europe. A proposed framework aims to develop indicators and decision support tools to track and assess climate-induced disease risks, improve early warning and response systems, and evaluate adaptation and mitigation measures. The approach involves multi-level engagement, innovative methodologies, and novel data streams with the goal of reducing the knowledge-to-action gap for improved health system resilience.
LANCET REGIONAL HEALTH-EUROPE
(2023)
Article
Environmental Sciences
Prasad Liyanage, Yesim Tozan, Hans J. Overgaard, Hasitha Aravinda Tissera, Joacim Rocklov
Summary: This study aimed to quantify the effect of weather variability on dengue vector indices in Kalutara, Sri Lanka. The findings showed that rainfall, temperature, and El Nino events were associated with an increased relative risk of dengue vector indices. Container index was found to be less sensitive to temperature and El Nino, and rainfall.
LANCET PLANETARY HEALTH
(2022)
Article
Health Care Sciences & Services
Zia Farooq, Joacim Rockloev, Jonas Wallin, Najmeh Abiri, Maquines Odhiambo Sewe, Henrik Sjodin, Jan C. Semenza
Summary: The study used advanced artificial intelligence to analyze the eco-climatic drivers of West Nile virus outbreaks in Europe. The research found that anomalies in summer/spring temperatures, lower water availability index (NDWI), and drier winter conditions were the main determinants of WNV outbreaks across Europe. The AI-based framework showed high discriminatory power in predicting WNV-endemic areas and can be used for timely surveillance and control measures.
LANCET REGIONAL HEALTH-EUROPE
(2022)
